STRINGSTRING
ABL1 ABL1 ARHGEF5 ARHGEF5 SORBS3 SORBS3 NRP1 NRP1 SERPINF2 SERPINF2 EPHA1 EPHA1 LIMCH1 LIMCH1 S100A10 S100A10 ARHGEF10 ARHGEF10 BRAF BRAF TGFB3 TGFB3 LPAR1 LPAR1 TESK1 TESK1 WNT11 WNT11 FERMT2 FERMT2 EVL EVL ITGB1BP1 ITGB1BP1 MYOC MYOC LIMK1 LIMK1 SFRP1 SFRP1 ARHGEF10L ARHGEF10L SYNPO2L SYNPO2L RAPGEF3 RAPGEF3 BAG4 BAG4 PFN2 PFN2 PPM1E PPM1E TGFBR1 TGFBR1 CCDC88A CCDC88A CCN2 CCN2 CARMIL1 CARMIL1 MTOR MTOR ARHGEF15 ARHGEF15 PAK1 PAK1 NF2 NF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABL1Tyrosine-protein kinase. (1150 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1522 aa)
SORBS3Sorbin and SH3 domain containing 3. (676 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (565 aa)
EPHA1EPH receptor A1. (976 aa)
LIMCH1LIM and calponin homology domains 1. (1529 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1359 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (804 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
TESK1Testis associated actin remodelling kinase 1. (628 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FERMT2Fermitin family member 2. (706 aa)
EVLEnah/Vasp-like. (461 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (213 aa)
MYOCMyocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...] (498 aa)
LIMK1LIM domain kinase 1. (763 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
ARHGEF10LRho guanine nucleotide exchange factor 10 like. (1282 aa)
SYNPO2LSynaptopodin 2 like. (973 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
BAG4BCL2 associated athanogene 4. (456 aa)
PFN2Profilin; Belongs to the profilin family. (188 aa)
PPM1EProtein phosphatase, Mg2+/Mn2+ dependent 1E. (754 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
CCDC88ACoiled-coil domain containing 88A. (1874 aa)
CCN2Cellular communication network factor 2. (477 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1420 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (843 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
NF2Neurofibromin 2. (596 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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