47 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFCAP00000030321	Uncharacterized protein. (79 aa)
	BAX	BCL2 associated X, apoptosis regulator. (192 aa)
	PINK1	PTEN induced kinase 1. (581 aa)
	PIP5KL1	Phosphatidylinositol-4-phosphate 5-kinase like 1. (396 aa)
	FAM102A	Family with sequence similarity 102 member A. (384 aa)
	PRELID1	PRELI domain containing 1. (219 aa)
	LRRK2	Leucine rich repeat kinase 2. (2527 aa)
	RACK1	WD_REPEATS_REGION domain-containing protein. (424 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	M3W534_FELCA	Uncharacterized protein. (56 aa)
	BCO2	Beta-carotene oxygenase 2. (575 aa)
	HSH2D	Hematopoietic SH2 domain containing. (383 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1514 aa)
	M3WDH2_FELCA	Uncharacterized protein. (157 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa)
	MLLT11	MLLT11 transcription factor 7 cofactor. (90 aa)
	NDUFS1	NADH:ubiquinone oxidoreductase core subunit S1. (691 aa)
	SLC25A33	Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
	PARK7	Parkinsonism associated deglycase. (189 aa)
	DCN	Decorin; May affect the rate of fibrils formation. (360 aa)
	TUSC2	Tumor suppressor 2, mitochondrial calcium regulator. (110 aa)
	FAM102B	Family with sequence similarity 102 member B. (360 aa)
	PPP2R3C	Protein phosphatase 2 regulatory subunit B''gamma. (453 aa)
	PPA2	Pyrophosphatase (inorganic) 2. (342 aa)
	SLC4A11	Solute carrier family 4 member 11. (883 aa)
	SPART	Spartin. (672 aa)
	ENSFCAP00000028212	Uncharacterized protein. (83 aa)
	IFI6	Interferon alpha inducible protein 6. (149 aa)
	MFN1	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (804 aa)
	MYOC	Myocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...] (498 aa)
	PANK2	Pantothenate kinase 2. (570 aa)
	SRC	Tyrosine-protein kinase. (678 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
	GCLM	Glutamate-cysteine ligase modifier subunit. (274 aa)
	PID1	Phosphotyrosine interaction domain containing 1. (252 aa)
	STOX1	Storkhead box 1. (878 aa)
	SLC25A36	Solute carrier family 25 member 36; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
	BAD	BCL2 associated agonist of cell death. (273 aa)
	RNF122	Ring finger protein 122. (188 aa)
	BOK	BCL2 family apoptosis regulator BOK. (320 aa)
	STOML2	Stomatin like 2. (425 aa)
	HEBP2	Heme binding protein 2. (285 aa)
	PRDX3	Peroxiredoxin 3. (270 aa)
	BAK1	BCL2 antagonist/killer 1. (251 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (568 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	AKT3	ENSFCAP00000004586	ENSFCAP00000003410	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT1	BAD	ENSFCAP00000004586	ENSFCAP00000047559	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death.	0.948
AKT1	M3WDH2_FELCA	ENSFCAP00000004586	ENSFCAP00000009798	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.402
AKT1	PPP2R3C	ENSFCAP00000004586	ENSFCAP00000024277	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein phosphatase 2 regulatory subunit B''gamma.	0.655
AKT1	SRC	ENSFCAP00000004586	ENSFCAP00000041142	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.518
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	AKT3	ENSFCAP00000059662	ENSFCAP00000003410	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.918
AKT2	BAD	ENSFCAP00000059662	ENSFCAP00000047559	Non-specific serine/threonine protein kinase.	BCL2 associated agonist of cell death.	0.948
AKT2	M3WDH2_FELCA	ENSFCAP00000059662	ENSFCAP00000009798	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.402
AKT2	PPP2R3C	ENSFCAP00000059662	ENSFCAP00000024277	Non-specific serine/threonine protein kinase.	Protein phosphatase 2 regulatory subunit B''gamma.	0.655
AKT2	SRC	ENSFCAP00000059662	ENSFCAP00000041142	Non-specific serine/threonine protein kinase.	Tyrosine-protein kinase.	0.519
AKT3	AKT1	ENSFCAP00000003410	ENSFCAP00000004586	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT3	AKT2	ENSFCAP00000003410	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.918
AKT3	BAD	ENSFCAP00000003410	ENSFCAP00000047559	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death.	0.948
AKT3	M3WDH2_FELCA	ENSFCAP00000003410	ENSFCAP00000009798	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.402
AKT3	PPP2R3C	ENSFCAP00000003410	ENSFCAP00000024277	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein phosphatase 2 regulatory subunit B''gamma.	0.655
AKT3	SRC	ENSFCAP00000003410	ENSFCAP00000041142	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.517
BAD	AKT1	ENSFCAP00000047559	ENSFCAP00000004586	BCL2 associated agonist of cell death.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.948
BAD	AKT2	ENSFCAP00000047559	ENSFCAP00000059662	BCL2 associated agonist of cell death.	Non-specific serine/threonine protein kinase.	0.948