STRINGSTRING
NODAL NODAL CSMD2 CSMD2 TPPP3 TPPP3 GHRL GHRL GHSR GHSR CYP27C1 CYP27C1 CBS CBS BMPR2 BMPR2 CYP27B1 CYP27B1 JUNB JUNB LDOC1 LDOC1 DEDD DEDD ESR1 ESR1 VDR VDR PTN PTN CITED2 CITED2 CSMD1 CSMD1 HAVCR2 HAVCR2 DAZAP1 DAZAP1 LIF LIF ASH1L ASH1L PRDM1 PRDM1 HMX3 HMX3 ENSFCAP00000042577 ENSFCAP00000042577 MED1 MED1 ENSFCAP00000049367 ENSFCAP00000049367 STOX2 STOX2 PRDX3 PRDX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NODALNodal growth differentiation factor. (348 aa)
CSMD2CUB and Sushi multiple domains 2. (3632 aa)
TPPP3Tubulin polymerization promoting protein family member 3. (176 aa)
GHRLAppetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family. (117 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (580 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (633 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
LDOC1LDOC1 regulator of NFKB signaling. (146 aa)
DEDDDeath effector domain containing. (318 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
VDRVitamin D receptor. (441 aa)
PTNPleiotrophin. (179 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
CSMD1CUB and Sushi multiple domains 1. (3501 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (280 aa)
DAZAP1DAZ associated protein 1. (406 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
ASH1LASH1 like histone lysine methyltransferase. (2965 aa)
PRDM1PR/SET domain 1. (821 aa)
HMX3H6 family homeobox 3. (357 aa)
ENSFCAP00000042577DUF4939 domain-containing protein. (113 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
ENSFCAP00000049367annotation not available (113 aa)
STOX2Storkhead box 2. (926 aa)
PRDX3Peroxiredoxin 3. (270 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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