STRINGSTRING
LEF1 LEF1 BRAF BRAF CRISPLD2 CRISPLD2 ALDH1A3 ALDH1A3 PDGFRA PDGFRA MKKS MKKS HOXB3 HOXB3 EP300 EP300 CRISPLD1 CRISPLD1 NIPBL NIPBL CHD7 CHD7 SGPL1 SGPL1 ANKRD11 ANKRD11 ZIC3 ZIC3 RARG RARG MSX1 MSX1 TIPARP TIPARP RAB3GAP1 RAB3GAP1 NOG NOG RAF1 RAF1 BBS4 BBS4 MAPK3 MAPK3 STRA6 STRA6 EDNRA EDNRA LOC101094201 LOC101094201 ALDH1A2 ALDH1A2 PAX9 PAX9 DLX5 DLX5 ZFAND5 ZFAND5 PTPN11 PTPN11 MAPK1 MAPK1 RRAS RRAS SRF SRF CSRNP1 CSRNP1 TGFB3 TGFB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LEF1Lymphoid enhancer binding factor 1. (415 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (804 aa)
CRISPLD2Cysteine rich secretory protein LCCL domain containing 2. (497 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
HOXB3Homeobox B3. (359 aa)
EP300E1A binding protein p300. (2425 aa)
CRISPLD1Cysteine rich secretory protein LCCL domain containing 1. (500 aa)
NIPBLNipped-B protein. (2805 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (671 aa)
ANKRD11Ankyrin repeat domain 11. (2835 aa)
ZIC3Zic family member 3. (553 aa)
RARGRetinoic acid receptor gamma. (459 aa)
MSX1Msh homeobox 1. (303 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (692 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (1028 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
BBS4Bardet-Biedl syndrome 4. (525 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
STRA6Stimulated by retinoic acid 6. (700 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
LOC101094201SCHIP-1 domain-containing protein. (489 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (549 aa)
PAX9Paired box 9. (341 aa)
DLX5Homeobox domain-containing protein. (289 aa)
ZFAND5Zinc finger AN1-type containing 5. (213 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
RRASRAS related. (218 aa)
SRFSerum response factor. (512 aa)
CSRNP1Cysteine and serine rich nuclear protein 1. (574 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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