55 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP2	Bone morphogenetic protein 2. (395 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1222 aa)
	GDF10	Growth differentiation factor 10. (503 aa)
	BMP10	TGF_BETA_2 domain-containing protein. (424 aa)
	JADE2	Jade family PHD finger 2. (827 aa)
	BMP6	Bone morphogenetic protein 6. (502 aa)
	GDF6	TGF_BETA_2 domain-containing protein. (462 aa)
	HEXA	Beta-hexosaminidase. (530 aa)
	AFP	Alpha fetoprotein. (609 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
	SMAD6	Mothers against decapentaplegic homolog. (497 aa)
	ZMIZ1	Zinc finger MIZ-type containing 1. (1066 aa)
	GDF3	Growth differentiation factor 3. (365 aa)
	GDF15	Growth differentiation factor 15. (307 aa)
	HNF1A	HNF1 homeobox A. (639 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	BMP3	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
	RBM14	RNA binding motif protein 14. (669 aa)
	INHA	Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	INHBE	Inhibin subunit beta E. (349 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	NCEH1	Neutral cholesterol ester hydrolase 1. (439 aa)
	GDF11	Growth differentiation factor 11. (404 aa)
	SKI	SKI proto-oncogene. (730 aa)
	ENSFCAP00000061110	TGF_BETA_2 domain-containing protein. (362 aa)
	ENSFCAP00000058884	Protein kinase domain-containing protein. (375 aa)
	SMAD2	Mothers against decapentaplegic homolog. (721 aa)
	SLC33A1	Solute carrier family 33 member 1. (550 aa)
	LOC105261327	Left-right determination factor. (367 aa)
	ATOH8	Atonal bHLH transcription factor 8. (355 aa)
	LOC111559734	Bone morphogenetic protein 7. (426 aa)
	GDF7	Growth differentiation factor 7. (455 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	NUP93	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (827 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	VIM	Vimentin; Belongs to the intermediate filament family. (466 aa)
	BMP8B	TGF_BETA_2 domain-containing protein. (402 aa)
	ENSFCAP00000049360	PC4 domain-containing protein. (119 aa)
	FOS	Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
	LOC101092676	TGF_BETA_2 domain-containing protein. (410 aa)
	INHBA	Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins (By similarity). (424 aa)
	SUB1	SUB1 regulator of transcription. (127 aa)
	SMAD7	Mothers against decapentaplegic homolog. (426 aa)
	SMAD9	Mothers against decapentaplegic homolog. (430 aa)
	BMP8A	TGF_BETA_2 domain-containing protein. (402 aa)
	INHBB	Inhibin subunit beta B. (407 aa)
	GDF5	Growth differentiation factor 5. (499 aa)
	SMAD3	Mothers against decapentaplegic homolog. (457 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	CITED1	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (221 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	INHBC	Inhibin subunit beta C. (353 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFP	BMP4	ENSFCAP00000021758	ENSFCAP00000051185	Alpha fetoprotein.	Bone morphogenetic protein 4.	0.484
AFP	GDF3	ENSFCAP00000021758	ENSFCAP00000009224	Alpha fetoprotein.	Growth differentiation factor 3.	0.482
AFP	HNF4A	ENSFCAP00000021758	ENSFCAP00000007578	Alpha fetoprotein.	Hepatocyte nuclear factor 4 alpha.	0.780
BMP10	BMP4	ENSFCAP00000025871	ENSFCAP00000051185	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 4.	0.448
BMP10	BMP5	ENSFCAP00000025871	ENSFCAP00000004147	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 5.	0.483
BMP10	GDF15	ENSFCAP00000025871	ENSFCAP00000009024	TGF_BETA_2 domain-containing protein.	Growth differentiation factor 15.	0.416
BMP10	SMAD3	ENSFCAP00000025871	ENSFCAP00000034334	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.542
BMP10	SMAD4	ENSFCAP00000025871	ENSFCAP00000031311	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.417
BMP10	SMAD5	ENSFCAP00000025871	ENSFCAP00000050960	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.452
BMP2	BMP4	ENSFCAP00000031036	ENSFCAP00000051185	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.932
BMP2	BMP5	ENSFCAP00000031036	ENSFCAP00000004147	Bone morphogenetic protein 2.	Bone morphogenetic protein 5.	0.514
BMP2	BMP6	ENSFCAP00000031036	ENSFCAP00000024856	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.953
BMP2	ENSFCAP00000061110	ENSFCAP00000031036	ENSFCAP00000061110	Bone morphogenetic protein 2.	TGF_BETA_2 domain-containing protein.	0.553
BMP2	GDF5	ENSFCAP00000031036	ENSFCAP00000035241	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.527
BMP2	LOC111559734	ENSFCAP00000031036	ENSFCAP00000051631	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.704
BMP2	SMAD1	ENSFCAP00000031036	ENSFCAP00000003810	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.806
BMP2	SMAD2	ENSFCAP00000031036	ENSFCAP00000057862	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.642
BMP2	SMAD3	ENSFCAP00000031036	ENSFCAP00000034334	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.586
BMP2	SMAD4	ENSFCAP00000031036	ENSFCAP00000031311	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.846
BMP2	SMAD5	ENSFCAP00000031036	ENSFCAP00000050960	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.793