STRINGSTRING
TCF21 TCF21 CDK5 CDK5 TREX1 TREX1 NPRL3 NPRL3 DIPK2A DIPK2A MEF2D MEF2D MTM1 MTM1 FOXH1 FOXH1 OSR1 OSR1 NOTCH1 NOTCH1 SRF SRF MYORG MYORG CAV2 CAV2 CBY1 CBY1 SEMA3C SEMA3C VWA5B1 VWA5B1 KDM6B KDM6B IHH IHH PROX1 PROX1 SAP30 SAP30 NPHS1 NPHS1 PTEN PTEN KRAS KRAS GPCPD1 GPCPD1 HOMER1 HOMER1 ANKRD1 ANKRD1 TNNC1 TNNC1 HEG1 HEG1 MYF5 MYF5 MYF6 MYF6 HAND1 HAND1 KEL KEL COL3A1 COL3A1 DLL4 DLL4 MAML1 MAML1 ADPRHL1 ADPRHL1 ACTC1 ACTC1 HIVEP3 HIVEP3 MYOZ1 MYOZ1 MYLPF MYLPF TIPARP TIPARP M3WIG1_FELCA M3WIG1_FELCA TBX20 TBX20 SELENON SELENON NUPR1 NUPR1 PATL2 PATL2 ACTG2 ACTG2 NRAP NRAP LMNA LMNA EMD EMD NEBL NEBL CSRP3 CSRP3 RARB RARB SLC9A1 SLC9A1 KLHL41 KLHL41 DSP DSP ZNF689 ZNF689 FHL2 FHL2 PDGFRA PDGFRA MYH6 MYH6 TBX2 TBX2 MESP1 MESP1 KLHL40 KLHL40 EGR2 EGR2 CFL2 CFL2 IFT20 IFT20 VWA5B2 VWA5B2 METTL8 METTL8 ACTA2 ACTA2 GTF3C5 GTF3C5 HOXD10 HOXD10 LRP2 LRP2 ZMPSTE24 ZMPSTE24 CHRND CHRND PLN PLN LEMD2 LEMD2 EP300 EP300 MYOD1 MYOD1 CACNA1S CACNA1S SMAD1 SMAD1 CHD7 CHD7 MYOZ2 MYOZ2 MYBPC3 MYBPC3 LRRC10 LRRC10 ENG ENG MYLK3 MYLK3 BCL9L BCL9L GATA5 GATA5 NKX2-5 NKX2-5 MYL6 MYL6 CSRP1 CSRP1 GJA5 GJA5 EYA1 EYA1 SIK1 SIK1 R3HDM2 R3HDM2 STAC3 STAC3 MTOR MTOR ALPK3 ALPK3 POPDC2 POPDC2 NDUFV2 NDUFV2 SHH SHH ENSFCAP00000060955 ENSFCAP00000060955 VGLL2 VGLL2 SMO SMO SVIL SVIL DLL1 DLL1 TNNI1 TNNI1 ACTA1 ACTA1 VRK3 VRK3 EYA2 EYA2 MYL2 MYL2 FOXL2 FOXL2 ANKRD33B ANKRD33B PTCD2 PTCD2 DMD DMD CCNT2 CCNT2 NF1 NF1 IFRD2 IFRD2 RYR2 RYR2 HNRNPU HNRNPU LOC109492241 LOC109492241 LOC101085169 LOC101085169 MAFF MAFF JARID2 JARID2 ACTN1 ACTN1 RIPOR2 RIPOR2 PPP1R13L PPP1R13L ELN ELN SIX4 SIX4 MYO18B MYO18B ASB2 ASB2 DNER DNER ZIC3 ZIC3 MYLK2 MYLK2 BMP4 BMP4 FOXN2 FOXN2 DLG1 DLG1 PITX1 PITX1 HLF HLF ACTN2 ACTN2 ZFPM1 ZFPM1 MYOCD MYOCD PRKAR1A PRKAR1A TBX3 TBX3 DLG2 DLG2 MYL7 MYL7 VWA5A VWA5A TGFBR1 TGFBR1 BIN3 BIN3 MSC MSC BVES BVES ATG5 ATG5 CSRP2 CSRP2 SRPK3 SRPK3 SGCG SGCG XIRP2 XIRP2 NOG NOG FOS FOS MEGF10 MEGF10 SOX9 SOX9 LOC101092676 LOC101092676 TENM4 TENM4 ZFPM2 ZFPM2 PTCH1 PTCH1 MED1 MED1 CXADR CXADR DMRTA2 DMRTA2 PHOX2B PHOX2B ZFAND5 ZFAND5 TSC1 TSC1 LRRC10B LRRC10B SMAD7 SMAD7 ARID2 ARID2 COL19A1 COL19A1 P2RX2 P2RX2 ALDH1A2 ALDH1A2 WNT10B WNT10B LOC101094201 LOC101094201 ZBTB18 ZBTB18 PLEC PLEC EDNRA EDNRA TCAP TCAP BTG2 BTG2 SOX8 SOX8 HOXD9 HOXD9 TBX5 TBX5 PPP3CA PPP3CA VAX1 VAX1 ALPK2 ALPK2 STRA6 STRA6 SGCD SGCD PGM5 PGM5 POPDC3 POPDC3 CDON CDON SRPK2 SRPK2 TGFB2 TGFB2 SAV1 SAV1 HLX HLX ITGB1 ITGB1 IRX3 IRX3 SMAD4 SMAD4 BMP2 BMP2 MEF2C MEF2C CAV3 CAV3 ENSFCAP00000030326 ENSFCAP00000030326 CAV1 CAV1 WNT2 WNT2 MYOG MYOG MYL10 MYL10 PRMT1 PRMT1 SMYD1 SMYD1 NKX2-6 NKX2-6 EGR1 EGR1 MYH14 MYH14 R3HDM1 R3HDM1 GJC1 GJC1 CD4H9orf24 CD4H9orf24 PKD2 PKD2 BMP10 BMP10 UTRN UTRN SGCZ SGCZ ATF3 ATF3 PPP3CB PPP3CB NOX4 NOX4 ACADM ACADM POGLUT1 POGLUT1 RB1 RB1 BMPR1A BMPR1A GATA6 GATA6 KLF5 KLF5 PKP2 PKP2 PRKAR1B PRKAR1B MEF2A MEF2A CITED2 CITED2 FGF9 FGF9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TCF21Transcription factor 21. (179 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
TREX1Three prime repair exonuclease 1. (314 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
DIPK2ADivergent protein kinase domain 2A. (430 aa)
MEF2DMyocyte enhancer factor 2D. (519 aa)
MTM1Myotubularin 1. (603 aa)
FOXH1Forkhead box H1. (361 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
NOTCH1Notch receptor 1. (2543 aa)
SRFSerum response factor. (512 aa)
MYORGMyogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (714 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (262 aa)
CBY1Chibby family member 1, beta catenin antagonist. (127 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (749 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1228 aa)
KDM6BLysine demethylase 6B. (1769 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
PROX1Prospero homeobox 1. (737 aa)
SAP30Sin3A associated protein 30. (221 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1241 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
KRASUncharacterized protein. (380 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (672 aa)
HOMER1Homer scaffold protein 1. (354 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
HEG1Heart development protein with EGF like domains 1. (1374 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYF6Myogenic factor 6. (242 aa)
HAND1Heart and neural crest derivatives expressed 1. (218 aa)
KELKell metallo-endopeptidase. (787 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa)
MAML1Mastermind like transcriptional coactivator 1. (1016 aa)
ADPRHL1ADP-ribosylhydrolase like 1. (354 aa)
ACTC1Actin alpha cardiac muscle 1. (616 aa)
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2382 aa)
MYOZ1Myozenin 1. (297 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (170 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (692 aa)
M3WIG1_FELCAUncharacterized protein. (351 aa)
TBX20T-box transcription factor 20. (480 aa)
SELENONSelenoprotein N. (556 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
PATL2SPG11 vesicle trafficking associated, spatacsin. (2444 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
NRAPNebulin related anchoring protein. (1734 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
EMDEmerin. (260 aa)
NEBLNebulette. (1011 aa)
CSRP3Cysteine and glycine rich protein 3. (271 aa)
RARBRetinoic acid receptor beta. (448 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (759 aa)
KLHL41Kelch like family member 41. (606 aa)
DSPDesmoplakin. (2884 aa)
ZNF689Zinc finger protein 689. (500 aa)
FHL2Four and a half LIM domains 2. (280 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
MYH6Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
TBX2T-box transcription factor 2. (713 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (261 aa)
KLHL40Kelch like family member 40. (625 aa)
EGR2Early growth response 2. (541 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
IFT20Intraflagellar transport 20. (158 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1246 aa)
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (407 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
GTF3C5General transcription factor IIIC subunit 5. (513 aa)
HOXD10Homeobox D10. (410 aa)
LRP2LDL receptor related protein 2. (4646 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
LEMD2LEM domain containing 2. (566 aa)
EP300E1A binding protein p300. (2425 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1871 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
MYOZ2Myozenin 2. (264 aa)
MYBPC3Myosin binding protein C, cardiac. (1273 aa)
LRRC10Leucine rich repeat containing 10. (279 aa)
ENGEndoglin. (654 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
BCL9LBCL9 like. (1393 aa)
GATA5GATA binding protein 5. (398 aa)
NKX2-5NK2 homeobox 5. (333 aa)
MYL6Myosin light chain 6. (161 aa)
CSRP1Cysteine and glycine rich protein 1. (247 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
SIK1Uncharacterized protein. (780 aa)
R3HDM2Uncharacterized protein. (1043 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa)
ALPK3Alpha kinase 3. (1639 aa)
POPDC2Popeye domain containing 2. (362 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (256 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (556 aa)
ENSFCAP00000060955SH3 domain-containing protein. (2870 aa)
VGLL2Vestigial like family member 2. (317 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa)
SVILSupervillin. (2361 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (731 aa)
TNNI1Troponin I1, slow skeletal type. (207 aa)
ACTA1Actin alpha 1, skeletal muscle. (457 aa)
VRK3VRK serine/threonine kinase 3. (453 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (657 aa)
MYL2Myosin light chain 2. (174 aa)
FOXL2Forkhead box L2. (357 aa)
ANKRD33BAnkyrin repeat domain 33B. (604 aa)
PTCD2Pentatricopeptide repeat domain 2. (388 aa)
DMDDystrophin. (3677 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (742 aa)
NF1Neurofibromin 1. (2856 aa)
IFRD2Interferon related developmental regulator 2. (495 aa)
RYR2Ryanodine receptor 2. (4967 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (899 aa)
LOC109492241Uncharacterized protein. (424 aa)
LOC101085169Uncharacterized protein. (431 aa)
MAFFMAF bZIP transcription factor F. (178 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1251 aa)
ACTN1Actinin alpha 1. (927 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1162 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (867 aa)
ELNElastin. (732 aa)
SIX4SIX homeobox 4. (784 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2584 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (670 aa)
DNERDelta/notch like EGF repeat containing. (744 aa)
ZIC3Zic family member 3. (553 aa)
MYLK2Myosin light chain kinase 2. (742 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
FOXN2Forkhead box N2. (439 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
PITX1Homeobox protein. (313 aa)
HLFHLF transcription factor, PAR bZIP family member. (497 aa)
ACTN2Actinin alpha 2. (910 aa)
ZFPM1Zinc finger protein, FOG family member 1. (992 aa)
MYOCDMyocardin. (962 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (569 aa)
TBX3T-box transcription factor 3. (745 aa)
DLG2Discs large MAGUK scaffold protein 2. (1012 aa)
MYL7Myosin light chain 7. (216 aa)
VWA5AVon Willebrand factor A domain containing 5A. (415 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
BIN3Bridging integrator 3. (352 aa)
MSCMusculin. (198 aa)
BVESBlood vessel epicardial substance. (360 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CSRP2Cysteine and glycine rich protein 2. (205 aa)
SRPK3SRSF protein kinase 3. (567 aa)
SGCGSarcoglycan gamma. (354 aa)
XIRP2Xin actin binding repeat containing 2. (3521 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
FOSProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
MEGF10Multiple EGF like domains 10. (1204 aa)
SOX9SRY-box transcription factor 9. (511 aa)
LOC101092676TGF_BETA_2 domain-containing protein. (410 aa)
TENM4Teneurin transmembrane protein 4. (2823 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
PTCH1Patched 1. (1451 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
CXADRUncharacterized protein. (352 aa)
DMRTA2DMRT like family A2. (535 aa)
PHOX2BPaired like homeobox 2B. (315 aa)
ZFAND5Zinc finger AN1-type containing 5. (213 aa)
TSC1TSC complex subunit 1. (1110 aa)
LRRC10BLeucine rich repeat containing 10B. (292 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
ARID2AT-rich interaction domain 2. (1874 aa)
COL19A1Collagen type XIX alpha 1 chain. (1132 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (459 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (549 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC101094201SCHIP-1 domain-containing protein. (489 aa)
ZBTB18Zinc finger and BTB domain containing 18. (531 aa)
PLECPlectin. (4686 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
TCAPTitin-cap. (143 aa)
BTG2BTG anti-proliferation factor 2. (162 aa)
SOX8SRY-box 8. (883 aa)
HOXD9Homeobox D9. (345 aa)
TBX5T-box transcription factor 5. (518 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
VAX1Ventral anterior homeobox 1. (372 aa)
ALPK2Alpha kinase 2. (2089 aa)
STRA6Stimulated by retinoic acid 6. (700 aa)
SGCDSarcoglycan delta. (289 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
POPDC3Popeye domain containing 3. (291 aa)
CDONCell adhesion associated, oncogene regulated. (1283 aa)
SRPK2SRSF protein kinase 2. (754 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SAV1Salvador family WW domain containing protein 1. (395 aa)
HLXH2.0 like homeobox. (569 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa)
IRX3Iroquois homeobox 3. (502 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa)
ENSFCAP00000030326Uncharacterized protein. (122 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
MYOGMyogenin. (249 aa)
MYL10Myosin light chain 10. (167 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
NKX2-6NK2 homeobox 6. (299 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2039 aa)
R3HDM1R3H domain containing 1. (1133 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
CD4H9orf24Chromosome D4 C9orf24 homolog. (298 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (970 aa)
BMP10TGF_BETA_2 domain-containing protein. (424 aa)
UTRNUtrophin. (3433 aa)
SGCZSarcoglycan zeta. (312 aa)
ATF3Activating transcription factor 3. (259 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
NOX4NADPH oxidase 4. (578 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (445 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
RB1RB transcriptional corepressor 1. (930 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GATA6GATA binding protein 6. (646 aa)
KLF5Kruppel like factor 5. (457 aa)
PKP2Plakophilin 2. (1014 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (378 aa)
MEF2AMyocyte enhancer factor 2A. (542 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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