Your Input: | |||||
| SCRIB | Scribble planar cell polarity protein. (1637 aa) | ||||
| NODAL | Nodal growth differentiation factor. (348 aa) | ||||
| ENG | Endoglin. (654 aa) | ||||
| TEAD2 | TEA domain transcription factor 2. (451 aa) | ||||
| KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (836 aa) | ||||
| CSMD2 | CUB and Sushi multiple domains 2. (3632 aa) | ||||
| TRIM71 | Tripartite motif containing 71. (874 aa) | ||||
| PML | Promyelocytic leukemia. (876 aa) | ||||
| HIF1A | Hypoxia inducible factor 1 subunit alpha. (825 aa) | ||||
| CTNNB1 | Catenin beta 1. (783 aa) | ||||
| MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (979 aa) | ||||
| PAK1 | Non-specific serine/threonine protein kinase. (544 aa) | ||||
| FUZ | Fuzzy planar cell polarity protein. (419 aa) | ||||
| LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (951 aa) | ||||
| CTHRC1 | Collagen triple helix repeat containing 1. (244 aa) | ||||
| ABL1 | Tyrosine-protein kinase. (1150 aa) | ||||
| LRP2 | LDL receptor related protein 2. (4646 aa) | ||||
| GZF1 | GDNF inducible zinc finger protein 1. (715 aa) | ||||
| MMP14 | Matrix metallopeptidase 14. (582 aa) | ||||
| LHX2 | LIM homeobox 2. (406 aa) | ||||
| RASIP1 | Ras interacting protein 1. (943 aa) | ||||
| VASP | Vasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa) | ||||
| DVL1 | Dishevelled segment polarity protein 1. (700 aa) | ||||
| CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa) | ||||
| EPHA4 | EPH receptor A4. (986 aa) | ||||
| SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) | ||||
| DVL3 | Dishevelled segment polarity protein 3. (718 aa) | ||||
| MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa) | ||||
| HS2ST1 | Heparan sulfate 2-O-sulfotransferase 1. (396 aa) | ||||
| LGR5 | Leucine rich repeat containing G protein-coupled receptor 5. (907 aa) | ||||
| CECR2 | CECR2 histone acetyl-lysine reader. (1527 aa) | ||||
| CCDC40 | Coiled-coil domain containing 40. (1152 aa) | ||||
| GREB1 | Growth regulating estrogen receptor binding 1. (1943 aa) | ||||
| LAMA1 | Laminin subunit alpha 1. (3080 aa) | ||||
| MESP1 | Mesoderm posterior bHLH transcription factor 1. (261 aa) | ||||
| TBX2 | T-box transcription factor 2. (713 aa) | ||||
| PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4078 aa) | ||||
| KDM6A | Lysine demethylase 6A. (1453 aa) | ||||
| NOTCH2 | Notch receptor 2. (2493 aa) | ||||
| KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1514 aa) | ||||
| LOC101084362 | Uncharacterized protein. (802 aa) | ||||
| PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa) | ||||
| EPHA2 | EPH receptor A2. (936 aa) | ||||
| MIB1 | Mindbomb E3 ubiquitin protein ligase 1. (1016 aa) | ||||
| DDR1 | Discoidin domain receptor tyrosine kinase 1. (921 aa) | ||||
| CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (569 aa) | ||||
| IFT52 | Intraflagellar transport 52. (446 aa) | ||||
| TCTN1 | Tectonic family member 1. (589 aa) | ||||
| DNAAF1 | Dynein assembly factor 1, axonemal. (641 aa) | ||||
| CCM2 | CCM2 scaffold protein. (453 aa) | ||||
| PLXNB2 | Plexin B2. (1841 aa) | ||||
| GLI3 | GLI family zinc finger 3. (1578 aa) | ||||
| TIMELESS | Timeless circadian regulator. (1211 aa) | ||||
| MKS1 | MKS transition zone complex subunit 1. (627 aa) | ||||
| SHROOM3 | Shroom family member 3. (1994 aa) | ||||
| RET | Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1138 aa) | ||||
| TBX20 | T-box transcription factor 20. (480 aa) | ||||
| KDM5B | Lysine demethylase 5B. (1544 aa) | ||||
| SPRY1 | Sprouty RTK signaling antagonist 1. (362 aa) | ||||
| PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1. (1365 aa) | ||||
| DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa) | ||||
| PRICKLE1 | Prickle planar cell polarity protein 1. (830 aa) | ||||
| EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa) | ||||
| HAND1 | Heart and neural crest derivatives expressed 1. (218 aa) | ||||
| TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1137 aa) | ||||
| ILK | Integrin linked kinase. (451 aa) | ||||
| KRAS | Uncharacterized protein. (380 aa) | ||||
| GRHL3 | Grainyhead like transcription factor 3. (602 aa) | ||||
| CCDC103 | Coiled-coil domain containing 103. (249 aa) | ||||
| LRRC1 | Leucine rich repeat containing 1. (524 aa) | ||||
| PRKX | Uncharacterized protein. (416 aa) | ||||
| FOXF1 | Forkhead box F1. (459 aa) | ||||
| SEMA3E | Semaphorin 3E; Belongs to the semaphorin family. (775 aa) | ||||
| IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) | ||||
| IFT57 | Intraflagellar transport 57. (429 aa) | ||||
| RALA | RAS like proto-oncogene A. (206 aa) | ||||
| RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) | ||||
| STK4 | Serine/threonine kinase 4. (487 aa) | ||||
| SRF | Serum response factor. (512 aa) | ||||
| NOTCH1 | Notch receptor 1. (2543 aa) | ||||
| OSR1 | Odd-skipped related transcription factor 1. (267 aa) | ||||
| WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) | ||||
| FOXH1 | Forkhead box H1. (361 aa) | ||||
| ESR1 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa) | ||||
| FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) | ||||
| FOXA1 | Forkhead box A1. (536 aa) | ||||
| VDR | Vitamin D receptor. (441 aa) | ||||
| PHB2 | Prohibitin. (299 aa) | ||||
| TCF21 | Transcription factor 21. (179 aa) | ||||
| FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) | ||||
| HESX1 | HESX homeobox 1. (207 aa) | ||||
| SPINT2 | Serine peptidase inhibitor, Kunitz type 2. (252 aa) | ||||
| LY6G5B | Lymphocyte antigen 6 family member G5B. (216 aa) | ||||
| CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa) | ||||
| GNA13 | G protein subunit alpha 13. (377 aa) | ||||
| LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1620 aa) | ||||
| LOC101091046 | Uncharacterized protein. (1716 aa) | ||||
| ARL13B | ADP ribosylation factor like GTPase 13B. (427 aa) | ||||
| LBX1 | Ladybird homeobox 1. (281 aa) | ||||
| PKD2 | Polycystin 2, transient receptor potential cation channel. (970 aa) | ||||
| LZTS2 | Leucine zipper tumor suppressor 2. (645 aa) | ||||
| MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (695 aa) | ||||
| CSMD1 | CUB and Sushi multiple domains 1. (3501 aa) | ||||
| MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa) | ||||
| KIF26B | Kinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1970 aa) | ||||
| MEF2C | MADS-box domain-containing protein. (483 aa) | ||||
| AREG | Amphiregulin. (323 aa) | ||||
| BMP2 | Bone morphogenetic protein 2. (395 aa) | ||||
| SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
| KLHL3 | Kelch like family member 3. (601 aa) | ||||
| IRX3 | Iroquois homeobox 3. (502 aa) | ||||
| CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa) | ||||
| NRARP | NOTCH regulated ankyrin repeat protein. (114 aa) | ||||
| CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (221 aa) | ||||
| FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa) | ||||
| BBS4 | Bardet-Biedl syndrome 4. (525 aa) | ||||
| GDNF | Glial cell derived neurotrophic factor. (211 aa) | ||||
| NKX2-1 | NK2 homeobox 1. (399 aa) | ||||
| KDM2B | Lysine demethylase 2B. (1264 aa) | ||||
| NPNT | Nephronectin. (612 aa) | ||||
| SMAD3 | Mothers against decapentaplegic homolog. (457 aa) | ||||
| GBX2 | Gastrulation brain homeobox 2. (348 aa) | ||||
| SETD2 | SET domain containing 2, histone lysine methyltransferase. (2563 aa) | ||||
| SFRP1 | Secreted frizzled related protein 1. (314 aa) | ||||
| MTSS1 | MTSS I-BAR domain containing 1. (856 aa) | ||||
| SALL4 | Spalt like transcription factor 4. (1058 aa) | ||||
| CNRIP1 | Uncharacterized protein. (324 aa) | ||||
| DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1921 aa) | ||||
| HHIP | Hedgehog interacting protein. (682 aa) | ||||
| PAX8 | Paired box 8. (620 aa) | ||||
| ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa) | ||||
| HOXA11 | Homeobox A11. (327 aa) | ||||
| AHI1 | Abelson helper integration site 1. (951 aa) | ||||
| SOX8 | SRY-box 8. (883 aa) | ||||
| COBL | Cordon-bleu WH2 repeat protein. (395 aa) | ||||
| LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (373 aa) | ||||
| ESRP2 | Epithelial splicing regulatory protein 2. (726 aa) | ||||
| SOSTDC1 | Sclerostin domain containing 1. (206 aa) | ||||
| LUZP1 | Leucine zipper protein 1. (1081 aa) | ||||
| LHX1 | LIM homeobox 1. (406 aa) | ||||
| TCAP | Titin-cap. (143 aa) | ||||
| SFRP2 | Secreted frizzled related protein 2. (385 aa) | ||||
| SLIT2 | Slit guidance ligand 2. (1543 aa) | ||||
| PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa) | ||||
| GREB1L | GREB1 like retinoic acid receptor coactivator. (1969 aa) | ||||
| SOX17 | SRY-box transcription factor 17. (406 aa) | ||||
| EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) | ||||
| GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) | ||||
| BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) | ||||
| SRC | Tyrosine-protein kinase. (678 aa) | ||||
| MED12 | Mediator complex subunit 12. (2278 aa) | ||||
| HES5 | Hes family bHLH transcription factor 5. (166 aa) | ||||
| GLMN | Glomulin, FKBP associated protein. (600 aa) | ||||
| MEGF8 | Multiple EGF like domains 8. (2789 aa) | ||||
| CC2D2A | Coiled-coil and C2 domain containing 2A. (1581 aa) | ||||
| WT1 | WT1 transcription factor. (523 aa) | ||||
| TSC1 | TSC complex subunit 1. (1110 aa) | ||||
| HECTD1 | HECT domain E3 ubiquitin protein ligase 1. (2610 aa) | ||||
| IRX2 | Iroquois homeobox 2. (456 aa) | ||||
| HAND2 | Heart and neural crest derivatives expressed 2. (275 aa) | ||||
| CLIC4 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa) | ||||
| EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) | ||||
| GATA3 | GATA binding protein 3. (444 aa) | ||||
| ARHGAP35 | Rho GTPase activating protein 35. (1500 aa) | ||||
| MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) | ||||
| TBX6 | T-box transcription factor 6. (436 aa) | ||||
| PTCH1 | Patched 1. (1451 aa) | ||||
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif 16. (1229 aa) | ||||
| SOX9 | SRY-box transcription factor 9. (511 aa) | ||||
| NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) | ||||
| NPHP3 | TPR_REGION domain-containing protein. (1348 aa) | ||||
| DVL2 | Dishevelled segment polarity protein 2. (735 aa) | ||||
| TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) | ||||
| LMO4 | LIM domain only 4. (165 aa) | ||||
| LOC111556166 | Uncharacterized protein. (804 aa) | ||||
| LEF1 | Lymphoid enhancer binding factor 1. (415 aa) | ||||
| DLG2 | Discs large MAGUK scaffold protein 2. (1012 aa) | ||||
| TBX3 | T-box transcription factor 3. (745 aa) | ||||
| WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
| COMMD5 | COMM domain containing 5. (224 aa) | ||||
| OPA1 | OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa) | ||||
| IRX1 | Iroquois homeobox 1. (485 aa) | ||||
| DAG1 | Peptidase S72 domain-containing protein. (892 aa) | ||||
| HOXA5 | Homeobox A5. (381 aa) | ||||
| YAP1 | Yes associated protein 1. (498 aa) | ||||
| NFATC4 | Nuclear factor of activated T cells 4. (930 aa) | ||||
| BCL10 | BCL10 immune signaling adaptor. (233 aa) | ||||
| SEMA4C | Semaphorin 4C; Belongs to the semaphorin family. (1000 aa) | ||||
| DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) | ||||
| RARG | Retinoic acid receptor gamma. (459 aa) | ||||
| BMP4 | Bone morphogenetic protein 4. (409 aa) | ||||
| HES1 | Hes family bHLH transcription factor 1. (280 aa) | ||||
| SOX4 | Transcription factor SOX. (459 aa) | ||||
| GDF7 | Growth differentiation factor 7. (455 aa) | ||||
| FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (170 aa) | ||||
| ZIC3 | Zic family member 3. (553 aa) | ||||
| SUFU | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (490 aa) | ||||
| PHACTR4 | Phosphatase and actin regulator. (752 aa) | ||||
| ASB2 | Ankyrin repeat and SOCS box containing 2. (670 aa) | ||||
| NKX3-1 | NK3 homeobox 1. (231 aa) | ||||
| RYR2 | Ryanodine receptor 2. (4967 aa) | ||||
| ENSFCAP00000055099 | Uncharacterized protein. (115 aa) | ||||
| AHI1-2 | Uncharacterized protein. (55 aa) | ||||
| CLUAP1 | Clusterin associated protein 1. (477 aa) | ||||
| ST14 | Suppression of tumorigenicity 14. (861 aa) | ||||
| CELSR1 | Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3085 aa) | ||||
| ENSFCAP00000057420 | Uncharacterized protein. (443 aa) | ||||
| TMEM59L | Transmembrane protein 59 like. (359 aa) | ||||
| CTSH | Cathepsin H; Belongs to the peptidase C1 family. (572 aa) | ||||
| PKD1 | Polycystin 1, transient receptor potential channel interacting. (4299 aa) | ||||
| NTN1 | Netrin 1. (715 aa) | ||||
| ETV4 | ETS variant 4. (488 aa) | ||||
| DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (731 aa) | ||||
| SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa) | ||||
| MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1382 aa) | ||||
| PODXL | Podocalyxin like. (594 aa) | ||||
| STK3 | Serine/threonine kinase 3. (573 aa) | ||||
| SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (556 aa) | ||||
| WNK4 | WNK lysine deficient protein kinase 4. (1322 aa) | ||||
| STARD13 | StAR related lipid transfer domain containing 13. (1127 aa) | ||||
| WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa) | ||||
| SEC24B | SEC24 homolog B, COPII coat complex component. (1259 aa) | ||||
| WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) | ||||
| PLXND1 | Plexin D1. (1927 aa) | ||||
| TULP3 | Tubby-like protein; Belongs to the TUB family. (462 aa) | ||||
| EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa) | ||||
| CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (362 aa) | ||||