STRINGSTRING
NCOA2 NCOA2 HSPB1 HSPB1 PSMA6 PSMA6 PAGR1 PAGR1 COMMD6 COMMD6 TAF7L TAF7L SLC30A9 SLC30A9 SP3 SP3 PROX1 PROX1 RBBP8 RBBP8 ZBTB8A ZBTB8A NR0B1 NR0B1 TACC1 TACC1 DDX54 DDX54 SP1 SP1 GFI1B GFI1B DHX9 DHX9 ANKRD1 ANKRD1 HCLS1 HCLS1 TAF10 TAF10 MED4 MED4 TRIM68 TRIM68 GATA4 GATA4 NCOA3 NCOA3 HAND1 HAND1 MED13 MED13 PRMT2 PRMT2 TADA3 TADA3 KDM1A KDM1A EPAS1 EPAS1 ANKRD2 ANKRD2 MMS19 MMS19 TBX20 TBX20 KEAP1 KEAP1 NFE2L2 NFE2L2 TAF4B TAF4B NR4A2 NR4A2 RNF6 RNF6 TP73 TP73 SIN3A SIN3A PRKCB PRKCB TTC8 TTC8 GATA1 GATA1 KDM3A KDM3A KLHL41 KLHL41 PADI2 PADI2 NOTCH2 NOTCH2 SMARCE1 SMARCE1 CDK5RAP3 CDK5RAP3 FBP1 FBP1 ATF4 ATF4 NR1H2 NR1H2 IWS1 IWS1 TGFB1I1 TGFB1I1 KLHL40 KLHL40 MTA2 MTA2 BBS2 BBS2 EGR2 EGR2 MKKS MKKS CREB1 CREB1 HNF4A HNF4A NRIP1 NRIP1 E4F1 E4F1 UBXN7 UBXN7 CSNK2B CSNK2B ETS2 ETS2 AR AR MED16 MED16 PITX2 PITX2 GTF2H1 GTF2H1 HDAC3 HDAC3 CHD4 CHD4 NFKBIA NFKBIA NR1H4 NR1H4 CREBBP CREBBP CCDC62 CCDC62 NR1I2 NR1I2 CRKL CRKL GTF2B GTF2B PARP1 PARP1 KAT6B KAT6B ZNF366 ZNF366 AHR AHR EP300 EP300 MYOD1 MYOD1 MLXIPL MLXIPL TRIB1 TRIB1 RNF25 RNF25 TRIM24 TRIM24 SMARCB1 SMARCB1 DAXX DAXX TOB2 TOB2 TAF6 TAF6 DDX5 DDX5 CTNNB1 CTNNB1 HIF1A HIF1A CRY2 CRY2 WWP2 WWP2 PIAS2 PIAS2 GTF2I GTF2I SETD1A SETD1A PDCD11 PDCD11 POU1F1 POU1F1 HDAC5 HDAC5 STAT3 STAT3 STAT5B STAT5B DDIT3 DDIT3 ASXL1 ASXL1 STING1 STING1 SNW1 SNW1 NSD1 NSD1 DTX3L DTX3L CTDP1 CTDP1 PARP9 PARP9 NKX2-5 NKX2-5 NR4A1 NR4A1 MAD2L2 MAD2L2 HIRA HIRA KAT8 KAT8 PRAME PRAME AIP AIP CPNE1 CPNE1 FAM162A FAM162A BBS1 BBS1 MED25 MED25 CTBP1 CTBP1 BHLHE41 BHLHE41 LOC101101073 LOC101101073 SPEN SPEN DLL1 DLL1 ENSFCAP00000059013 ENSFCAP00000059013 WIPI1 WIPI1 ENSFCAP00000058884 ENSFCAP00000058884 ELK1 ELK1 HMGB1 HMGB1 SMARCE1-2 SMARCE1-2 ETS1 ETS1 ENSFCAP00000057195 ENSFCAP00000057195 ARID5A ARID5A NRBF2 NRBF2 TAF4 TAF4 IFRD2 IFRD2 ENSFCAP00000055099 ENSFCAP00000055099 BRMS1 BRMS1 TP53BP2 TP53BP2 PPARGC1B PPARGC1B PPARGC1A PPARGC1A TACC2 TACC2 ENSFCAP00000053614 ENSFCAP00000053614 NKX3-1 NKX3-1 FAM220A FAM220A DCAF13 DCAF13 TRIP4 TRIP4 NR1H3 NR1H3 COMMD7 COMMD7 CTBP2 CTBP2 HES1 HES1 RARG RARG PITX1 PITX1 SMARCD3 SMARCD3 BCL10 BCL10 DAXX-2 DAXX-2 BCAS3 BCAS3 HMGA1 HMGA1 LOC101093046 LOC101093046 STRN STRN TCF7L2 TCF7L2 ZFPM1 ZFPM1 RXRA RXRA MYOCD MYOCD GSC GSC TBX3 TBX3 ENSFCAP00000048958 ENSFCAP00000048958 LEF1 LEF1 DUSP26 DUSP26 DACT1 DACT1 RELA RELA NR4A3 NR4A3 YWHAH YWHAH LHX3 LHX3 MLX MLX FOS FOS NIF3L1 NIF3L1 NHLH1 NHLH1 HES6 HES6 TP53 TP53 ZFPM2 ZFPM2 NCOA6 NCOA6 ARID1A ARID1A SRARP SRARP KAT6A KAT6A FAF1 FAF1 TBX6 TBX6 MED1 MED1 GATA3 GATA3 ARNT2 ARNT2 FOXP3 FOXP3 HAND2 HAND2 GSK3B GSK3B PTPN2 PTPN2 FOXP1 FOXP1 LDB1 LDB1 NCOA1 NCOA1 HMGA2 HMGA2 MDFIC MDFIC REST REST MED17 MED17 MED12 MED12 CRX CRX SOX17 SOX17 ZBTB7A ZBTB7A TAF7 TAF7 TRIB2 TRIB2 PRPF6 PRPF6 FIZ1 FIZ1 HEY2 HEY2 GTF2A1 GTF2A1 TBX5 TBX5 ARNT ARNT ENSFCAP00000036869 ENSFCAP00000036869 RNF14 RNF14 HDAC2 HDAC2 NCOA7 NCOA7 GBX2 GBX2 SMAD3 SMAD3 NKX2-1 NKX2-1 HIF1AN HIF1AN NCOR1 NCOR1 BHLHE40 BHLHE40 HDAC1 HDAC1 BBS4 BBS4 MED24 MED24 ANKRD42 ANKRD42 SMAD4 SMAD4 MEF2C MEF2C THRAP3 THRAP3 ARNTL ARNTL GRIP1 GRIP1 PKN1 PKN1 DMAP1 DMAP1 BBS5 BBS5 SIRT1 SIRT1 LOC101092829 LOC101092829 ACTN4 ACTN4 HIPK2 HIPK2 DCAF1 DCAF1 LRIF1 LRIF1 C1D C1D CRY1 CRY1 RB1 RB1 TCF3 TCF3 DNAAF4 DNAAF4 GATA6 GATA6 MEF2A MEF2A BUD31 BUD31 ATF2 ATF2 CITED2 CITED2 BBS7 BBS7 LATS1 LATS1 NHLH2 NHLH2 BRD8 BRD8 IFRD1 IFRD1 TCF21 TCF21 VDR VDR TMF1 TMF1 CNOT1 CNOT1 JUN JUN PPID PPID MED30 MED30 DDRGK1 DDRGK1 MEF2D MEF2D ESR1 ESR1 FOXH1 FOXH1 SRF SRF NFKBID NFKBID PARK7 PARK7 TP53BP1 TP53BP1 STK4 STK4 HEY1 HEY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCOA2Nuclear receptor coactivator. (1470 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
PSMA6Proteasome subunit alpha type. (251 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (254 aa)
COMMD6COMM domain containing 6. (85 aa)
TAF7LTATA-box binding protein associated factor 7 like. (489 aa)
SLC30A9Solute carrier family 30 member 9. (571 aa)
SP3Sp3 transcription factor. (713 aa)
PROX1Prospero homeobox 1. (737 aa)
RBBP8RB binding protein 8, endonuclease. (864 aa)
ZBTB8AZinc finger and BTB domain containing 8A. (441 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (471 aa)
TACC1Transforming acidic coiled-coil containing protein 1. (801 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (877 aa)
SP1Sp1 transcription factor. (786 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (327 aa)
DHX9DExH-box helicase 9. (1373 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (494 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
TRIM68Tripartite motif containing 68. (485 aa)
GATA4GATA binding protein 4. (443 aa)
NCOA3Nuclear receptor coactivator. (1412 aa)
HAND1Heart and neural crest derivatives expressed 1. (218 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
PRMT2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (434 aa)
TADA3Transcriptional adaptor 3. (432 aa)
KDM1ALysine demethylase 1A. (944 aa)
EPAS1Endothelial PAS domain protein 1. (872 aa)
ANKRD2Ankyrin repeat domain 2. (364 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
TBX20T-box transcription factor 20. (480 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
TAF4BTATA-box binding protein associated factor 4b. (869 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
RNF6Ring finger protein 6. (683 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (749 aa)
SIN3ASIN3 transcription regulator family member A. (1274 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
TTC8Tetratricopeptide repeat domain 8. (515 aa)
GATA1GATA binding protein 1. (413 aa)
KDM3ALysine demethylase 3A. (1324 aa)
KLHL41Kelch like family member 41. (606 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
NOTCH2Notch receptor 2. (2493 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (376 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (504 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
ATF4Activating transcription factor 4. (352 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (457 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (873 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (464 aa)
KLHL40Kelch like family member 40. (625 aa)
MTA2Metastasis associated 1 family member 2. (630 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (720 aa)
EGR2Early growth response 2. (541 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
NRIP1Nuclear receptor interacting protein 1. (1155 aa)
E4F1E4F transcription factor 1. (786 aa)
UBXN7UBX domain-containing protein. (519 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
ARAndrogen receptor. (903 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (828 aa)
PITX2Paired like homeodomain 2. (446 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
CHD4Uncharacterized protein. (1912 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
CREBBPCREB binding protein. (2444 aa)
CCDC62Coiled-coil domain containing 62. (687 aa)
NR1I2Nuclear receptor subfamily 1 group I member 2. (434 aa)
CRKLCRK like proto-oncogene, adaptor protein. (342 aa)
GTF2BGeneral transcription factor IIB. (285 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (979 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2063 aa)
ZNF366Zinc finger protein 366. (845 aa)
AHRUncharacterized protein. (849 aa)
EP300E1A binding protein p300. (2425 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
MLXIPLMLX interacting protein like. (857 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
RNF25Ring finger protein 25. (457 aa)
TRIM24Tripartite motif containing 24. (1268 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (429 aa)
DAXXDeath domain associated protein. (748 aa)
TOB2Transducer of ERBB2, 2. (335 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
CTNNB1Catenin beta 1. (783 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (825 aa)
CRY2Cryptochrome circadian regulator 2. (594 aa)
WWP2E3 ubiquitin-protein ligase. (875 aa)
PIAS2Protein inhibitor of activated STAT 2. (621 aa)
GTF2IGeneral transcription factor IIi. (999 aa)
SETD1ASET domain containing 1A, histone lysine methyltransferase. (1707 aa)
PDCD11Programmed cell death 11. (1871 aa)
POU1F1POU domain protein. (291 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1152 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
DDIT3DNA damage inducible transcript 3. (167 aa)
ASXL1ASXL transcriptional regulator 1. (1545 aa)
STING1Stimulator of interferon genes. (377 aa)
SNW1SNW domain containing 1. (570 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2701 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (738 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (939 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (828 aa)
NKX2-5NK2 homeobox 5. (333 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
HIRAProtein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1133 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (462 aa)
PRAMEPreferentially expressed antigen in melanoma. (512 aa)
AIPPeptidylprolyl isomerase. (690 aa)
CPNE1Copine 1. (542 aa)
FAM162AFamily with sequence similarity 162 member A. (167 aa)
BBS1BBS1 domain-containing protein. (602 aa)
MED25Mediator complex subunit 25. (795 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (467 aa)
BHLHE41Basic helix-loop-helix family member e41. (558 aa)
LOC101101073Uncharacterized protein. (971 aa)
SPENSpen family transcriptional repressor. (3678 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (731 aa)
ENSFCAP00000059013Uncharacterized protein. (82 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (470 aa)
ENSFCAP00000058884Protein kinase domain-containing protein. (375 aa)
ELK1ETS transcription factor ELK1. (487 aa)
HMGB1Uncharacterized protein. (233 aa)
SMARCE1-2HMG box domain-containing protein. (139 aa)
ETS1ETS proto-oncogene 1, transcription factor. (503 aa)
ENSFCAP00000057195Uncharacterized protein. (34 aa)
ARID5AAT-rich interaction domain 5A. (608 aa)
NRBF2Nuclear receptor binding factor 2. (288 aa)
TAF4TATA-box binding protein associated factor 4. (1099 aa)
IFRD2Interferon related developmental regulator 2. (495 aa)
ENSFCAP00000055099Uncharacterized protein. (115 aa)
BRMS1BRMS1 transcriptional repressor and anoikis regulator. (321 aa)
TP53BP2Tumor protein p53 binding protein 2. (1211 aa)
PPARGC1BPPARG coactivator 1 beta. (1006 aa)
PPARGC1APPARG coactivator 1 alpha. (803 aa)
TACC2Transforming acidic coiled-coil containing protein 2. (2952 aa)
ENSFCAP00000053614Uncharacterized protein. (81 aa)
NKX3-1NK3 homeobox 1. (231 aa)
FAM220AFAM220 domain-containing protein. (259 aa)
DCAF13DDB1 and CUL4 associated factor 13. (450 aa)
TRIP4Thyroid hormone receptor interactor 4. (605 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (498 aa)
COMMD7COMM domain-containing protein. (417 aa)
CTBP2C-terminal binding protein 2. (977 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
RARGRetinoic acid receptor gamma. (459 aa)
PITX1Homeobox protein. (313 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
DAXX-2Daxx domain-containing protein. (769 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (959 aa)
HMGA1High mobility group AT-hook 1. (107 aa)
LOC101093046Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (208 aa)
STRNStriatin. (780 aa)
TCF7L2Transcription factor 7 like 2. (673 aa)
ZFPM1Zinc finger protein, FOG family member 1. (992 aa)
RXRARetinoid X receptor alpha. (654 aa)
MYOCDMyocardin. (962 aa)
GSCGoosecoid homeobox. (256 aa)
TBX3T-box transcription factor 3. (745 aa)
ENSFCAP00000048958BHLH domain-containing protein. (109 aa)
LEF1Lymphoid enhancer binding factor 1. (415 aa)
DUSP26Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (219 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (840 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (651 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta. (69 aa)
LHX3LIM homeobox 3. (403 aa)
MLXMAX dimerization protein MLX. (288 aa)
FOSProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
NIF3L1NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. (376 aa)
NHLH1Nescient helix-loop-helix 1. (133 aa)
HES6Hes family bHLH transcription factor 6. (224 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
NCOA6Nuclear receptor coactivator 6. (2080 aa)
ARID1AAT-rich interaction domain 1A. (2284 aa)
SRARPSteroid receptor associated and regulated protein. (169 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2012 aa)
FAF1Fas associated factor 1. (668 aa)
TBX6T-box transcription factor 6. (436 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
GATA3GATA binding protein 3. (444 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2. (717 aa)
FOXP3Forkhead box P3. (501 aa)
HAND2Heart and neural crest derivatives expressed 2. (275 aa)
GSK3BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (416 aa)
FOXP1Forkhead box P1. (693 aa)
LDB1LIM domain binding 1. (411 aa)
NCOA1Nuclear receptor coactivator. (1492 aa)
HMGA2Uncharacterized protein. (109 aa)
MDFICMyoD family inhibitor domain containing. (244 aa)
RESTRE1 silencing transcription factor. (1045 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (692 aa)
MED12Mediator complex subunit 12. (2278 aa)
CRXCone-rod homeobox protein. (299 aa)
SOX17SRY-box transcription factor 17. (406 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
TAF7TATA-box binding protein associated factor 7. (349 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
PRPF6Pre-mRNA processing factor 6. (955 aa)
FIZ1FLT3 interacting zinc finger 1. (581 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
TBX5T-box transcription factor 5. (518 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (790 aa)
ENSFCAP00000036869Proteasome subunit alpha type. (197 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
HDAC2Histone deacetylase 2. (602 aa)
NCOA7Nuclear receptor coactivator 7. (942 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
SMAD3Mothers against decapentaplegic homolog. (457 aa)
NKX2-1NK2 homeobox 1. (399 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (349 aa)
NCOR1Nuclear receptor corepressor 1. (2515 aa)
BHLHE40Basic helix-loop-helix family member e40. (412 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa)
BBS4Bardet-Biedl syndrome 4. (525 aa)
MED24Mediator complex subunit 24. (1023 aa)
ANKRD42Ankyrin repeat domain 42. (551 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
THRAP3Thyroid hormone receptor associated protein 3. (958 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (626 aa)
GRIP1Glutamate receptor interacting protein 1. (1128 aa)
PKN1Protein kinase N1. (1064 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (663 aa)
BBS5Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...] (341 aa)
SIRT1Sirtuin 1. (745 aa)
LOC101092829Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (165 aa)
ACTN4Actinin alpha 4. (933 aa)
HIPK2Homeodomain interacting protein kinase 2. (1222 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1507 aa)
LRIF1Ligand dependent nuclear receptor interacting factor 1. (762 aa)
C1DC1D nuclear receptor corepressor. (178 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
RB1RB transcriptional corepressor 1. (930 aa)
TCF3Transcription factor 3. (654 aa)
DNAAF4Dynein axonemal assembly factor 4. (475 aa)
GATA6GATA binding protein 6. (646 aa)
MEF2AMyocyte enhancer factor 2A. (542 aa)
BUD31BUD31 homolog. (144 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
BRD8Bromodomain containing 8. (1236 aa)
IFRD1Interferon related developmental regulator 1. (450 aa)
TCF21Transcription factor 21. (179 aa)
VDRVitamin D receptor. (441 aa)
TMF1TATA element modulatory factor 1. (1093 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2383 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
MED30Mediator complex subunit 30. (178 aa)
DDRGK1DDRGK domain containing 1. (340 aa)
MEF2DMyocyte enhancer factor 2D. (519 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
FOXH1Forkhead box H1. (361 aa)
SRFSerum response factor. (512 aa)
NFKBIDNFKB inhibitor delta. (457 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
TP53BP1Tumor protein p53 binding protein 1. (1977 aa)
STK4Serine/threonine kinase 4. (487 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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