STRINGSTRING
ECM1 ECM1 ANGPTL7 ANGPTL7 ADAMTSL4 ADAMTSL4 P3H2 P3H2 EFEMP1 EFEMP1 LGALSL LGALSL COL9A3 COL9A3 COL14A1 COL14A1 ANGPTL5 ANGPTL5 ADAMTS5 ADAMTS5 SERPINE2 SERPINE2 PODNL1 PODNL1 DEF8 DEF8 THBS4 THBS4 FREM1 FREM1 LAMB1 LAMB1 LAMB4 LAMB4 COL1A1 COL1A1 TNC TNC LAMC3 LAMC3 PXDNL PXDNL PLOD3 PLOD3 SPARC SPARC BCAN BCAN THBS3 THBS3 GPC4 GPC4 RELL2 RELL2 LOXL3 LOXL3 AMTN AMTN ATRN ATRN FBLN2 FBLN2 TIMP1 TIMP1 ADAMTS15 ADAMTS15 VTN VTN LAMA1 LAMA1 COL4A4 COL4A4 ANGPTL2 ANGPTL2 TINAG TINAG FN1 FN1 LOXL4 LOXL4 SMOC1 SMOC1 LAMA3 LAMA3 FBN2 FBN2 LAMB2 LAMB2 RTBDN RTBDN EGFLAM EGFLAM COL9A1 COL9A1 LAMC2 LAMC2 GPC2 GPC2 ZP4 ZP4 NID1 NID1 FRAS1 FRAS1 ANGPTL3 ANGPTL3 PRG3 PRG3 THBS1 THBS1 CILP CILP LOXL1 LOXL1 COCH COCH OMD OMD ECM2 ECM2 LOXL2 LOXL2 EGFL6 EGFL6 COL6A3 COL6A3 F3 F3 MMRN1 MMRN1 ADAMTS1 ADAMTS1 ZP3 ZP3 TECTA TECTA COL6A6 COL6A6 OTOL1 OTOL1 COL2A1 COL2A1 TGFB3 TGFB3 ANGPT2 ANGPT2 TNR TNR COL3A1 COL3A1 COL4A1 COL4A1 COL6A1 COL6A1 FBN3 FBN3 ZP2 ZP2 ANGPTL4 ANGPTL4 FBN1 FBN1 COL16A1 COL16A1 PTPRZ1 PTPRZ1 ADAMTS2 ADAMTS2 COL28A1 COL28A1 PRELP PRELP F2 F2 VWA1 VWA1 COL21A1 COL21A1 LAMC1 LAMC1 MATN1 MATN1 EMILIN1 EMILIN1 FREM3 FREM3 NTN5 NTN5 LOC101093938 LOC101093938 LAD1 LAD1 LRRC15 LRRC15 GPC6 GPC6 ANGPT4 ANGPT4 ATRNL1 ATRNL1 PRG4 PRG4 LAMB3 LAMB3 LOC111556258 LOC111556258 COL6A2 COL6A2 IGFBP7 IGFBP7 ENSFCAP00000027665 ENSFCAP00000027665 LUM LUM USH2A USH2A GPC1 GPC1 WNT2 WNT2 KAZALD1 KAZALD1 GPC5 GPC5 TIMP3 TIMP3 CASK CASK MEGF9 MEGF9 COL5A2 COL5A2 THBS2 THBS2 CCDC80 CCDC80 MYOC MYOC NAV2 NAV2 TGFB2 TGFB2 FGF10 FGF10 FMOD FMOD IMPG2 IMPG2 ITGB4 ITGB4 FREM2 FREM2 NPNT NPNT ZP1 ZP1 SFRP1 SFRP1 RBP3 RBP3 LTBP4 LTBP4 TNN TNN PXDN PXDN MGP MGP FGL2 FGL2 ADAMTS8 ADAMTS8 SFRP2 SFRP2 GPC3 GPC3 NTNG2 NTNG2 SNORC SNORC VWF VWF EFNA5 EFNA5 LTBP1 LTBP1 POSTN POSTN COL4A3 COL4A3 COL4A6 COL4A6 NTN4 NTN4 MATN3 MATN3 VIT VIT PCSK6 PCSK6 ANXA2 ANXA2 COL5A1 COL5A1 ANGPT1 ANGPT1 ENSFCAP00000046833 ENSFCAP00000046833 MATN4 MATN4 MFAP4 MFAP4 COL4A5 COL4A5 FGL1 FGL1 COL10A1 COL10A1 NID2 NID2 ABI3BP ABI3BP VWC2 VWC2 DAG1 DAG1 COL6A5 COL6A5 FBLN1 FBLN1 COL11A1 COL11A1 LTBP3 LTBP3 AMELX AMELX SOD3 SOD3 RARRES2 RARRES2 VWA2 VWA2 ENSFCAP00000052562 ENSFCAP00000052562 ELN ELN NTN3 NTN3 COL5A3 COL5A3 COL4A2 COL4A2 LOC101095538 LOC101095538 LAMA2 LAMA2 COL17A1 COL17A1 ENSFCAP00000053888 ENSFCAP00000053888 LAMA4 LAMA4 ENSFCAP00000054558 ENSFCAP00000054558 CHADL CHADL COMP COMP AGRN AGRN VCAN VCAN COL25A1 COL25A1 COL20A1 COL20A1 SSC5D SSC5D FBLN5 FBLN5 ENSFCAP00000057142 ENSFCAP00000057142 SMOC2 SMOC2 ENSFCAP00000057337 ENSFCAP00000057337 MMRN2 MMRN2 NTN1 NTN1 COL9A2 COL9A2 HAPLN4 HAPLN4 IMPG1 IMPG1 RNASE4 RNASE4 ANGPTL1 ANGPTL1 ANGPTL6 ANGPTL6 SPARCL1 SPARCL1 LAMA5 LAMA5 CE1H17orf58 CE1H17orf58 FIBCD1 FIBCD1 NTNG1 NTNG1 HSPG2 HSPG2 MATN2 MATN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ECM1Extracellular matrix protein 1. (562 aa)
ANGPTL7Angiopoietin like 7. (344 aa)
ADAMTSL4ADAMTS like 4. (1061 aa)
P3H2Prolyl 3-hydroxylase 2. (707 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (504 aa)
LGALSLGalectin. (392 aa)
COL9A3Collagen type IX alpha 3 chain. (681 aa)
COL14A1Collagen type XIV alpha 1 chain. (1797 aa)
ANGPTL5Angiopoietin like 5. (388 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (930 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (484 aa)
PODNL1Podocan like 1. (622 aa)
DEF8Differentially expressed in FDCP 8 homolog. (563 aa)
THBS4Thrombospondin 4. (964 aa)
FREM1FRAS1 related extracellular matrix 1. (2155 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
LAMB4Laminin subunit beta 4. (1747 aa)
COL1A1Collagen type I alpha 1 chain. (1461 aa)
TNCTenascin C. (2200 aa)
LAMC3Laminin subunit gamma 3. (1573 aa)
PXDNLPeroxidasin like. (1457 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (740 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
BCANBrevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans; Belongs to the aggrecan/versican proteoglycan family. (908 aa)
THBS3Thrombospondin 3. (955 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
RELL2RELT like 2. (303 aa)
LOXL3Lysyl oxidase like 3. (974 aa)
AMTNAmelotin. (210 aa)
ATRNAttractin. (1418 aa)
FBLN2Fibulin 2. (1223 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (305 aa)
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (950 aa)
VTNSMB domain-containing protein. (468 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
COL4A4Collagen type IV alpha 4 chain. (1418 aa)
ANGPTL2Angiopoietin like 2. (493 aa)
TINAGTubulointerstitial nephritis antigen; Belongs to the peptidase C1 family. (474 aa)
FN1Fibronectin 1. (2475 aa)
LOXL4Lysyl oxidase like 4. (758 aa)
SMOC1SPARC related modular calcium binding 1. (639 aa)
LAMA3Laminin subunit alpha 3. (3332 aa)
FBN2Fibrillin 2. (2912 aa)
LAMB2Laminin subunit beta 2. (1801 aa)
RTBDNRetbindin. (223 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (1026 aa)
COL9A1Collagen type IX alpha 1 chain. (921 aa)
LAMC2Laminin subunit gamma 2. (1191 aa)
GPC2Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (610 aa)
ZP4Processed zona pellucida sperm-binding protein 4; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor; Belongs to the ZP domain family. ZPB subfamily. (570 aa)
NID1Nidogen 1. (1244 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4011 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
PRG3Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa)
THBS1Thrombospondin 1. (1170 aa)
CILPCartilage intermediate layer protein. (1183 aa)
LOXL1Lysyl oxidase like 1. (590 aa)
COCHCochlin. (680 aa)
OMDOsteomodulin. (415 aa)
ECM2Extracellular matrix protein 2. (710 aa)
LOXL2Lysyl oxidase like 2. (773 aa)
EGFL6EGF like domain multiple 6. (555 aa)
COL6A3Collagen type VI alpha 3 chain. (3178 aa)
F3Coagulation factor III, tissue factor. (379 aa)
MMRN1Multimerin 1. (1214 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (966 aa)
ZP3Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. (435 aa)
TECTATectorin alpha. (2155 aa)
COL6A6Collagen type VI alpha 6 chain. (2266 aa)
OTOL1Otolin 1. (474 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ANGPT2Angiopoietin 2. (494 aa)
TNRTenascin R. (1358 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
COL6A1Collagen type VI alpha 1 chain. (1027 aa)
FBN3Fibrillin 3. (2831 aa)
ZP2Processed zona pellucida sperm-binding protein 2; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor. (716 aa)
ANGPTL4Angiopoietin like 4. (414 aa)
FBN1Fibrillin 1. (2871 aa)
COL16A1Collagen type XVI alpha 1 chain. (1610 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2140 aa)
ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif 2. (1211 aa)
COL28A1Collagen type XXVIII alpha 1 chain. (1146 aa)
PRELPProline and arginine rich end leucine rich repeat protein. (379 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
VWA1Von Willebrand factor A domain containing 1. (415 aa)
COL21A1Collagen type XXI alpha 1 chain. (957 aa)
LAMC1Laminin subunit gamma 1. (1608 aa)
MATN1Matrilin 1. (539 aa)
EMILIN1Elastin microfibril interfacer 1. (1025 aa)
FREM3FRAS1 related extracellular matrix 3. (2234 aa)
NTN5Netrin 5. (489 aa)
LOC101093938Uncharacterized protein. (512 aa)
LAD1Ladinin-1; Anchoring filament protein which is a component of the basement membrane zone. (509 aa)
LRRC15Leucine rich repeat containing 15. (584 aa)
GPC6Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa)
ANGPT4Angiopoietin 4. (499 aa)
ATRNL1Attractin like 1. (1354 aa)
PRG4Uncharacterized protein. (389 aa)
LAMB3Laminin subunit beta 3. (1217 aa)
LOC111556258Fibrillar collagen NC1 domain-containing protein. (1736 aa)
COL6A2Collagen type VI alpha 2 chain. (1023 aa)
IGFBP7Insulin like growth factor binding protein 7. (282 aa)
ENSFCAP00000027665Uncharacterized protein. (1790 aa)
LUMLumican. (401 aa)
USH2AUsherin. (5203 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (557 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
KAZALD1Kazal type serine peptidase inhibitor domain 1. (302 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (570 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (935 aa)
MEGF9Multiple EGF like domains 9. (600 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
THBS2Thrombospondin 2. (1172 aa)
CCDC80Coiled-coil domain containing 80. (960 aa)
MYOCMyocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...] (498 aa)
NAV2Neuron navigator 2. (2451 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
FMODFibromodulin. (391 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1161 aa)
ITGB4Integrin beta. (1828 aa)
FREM2FRAS1 related extracellular matrix 2. (3175 aa)
NPNTNephronectin. (612 aa)
ZP1Zona pellucida glycoprotein 1. (634 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
RBP3Retinol binding protein 3. (1258 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1656 aa)
TNNTenascin N. (1120 aa)
PXDNPeroxidasin. (1502 aa)
MGPMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (215 aa)
FGL2Fibrinogen like 2. (440 aa)
ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif 8. (1046 aa)
SFRP2Secreted frizzled related protein 2. (385 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
NTNG2Netrin G2. (613 aa)
SNORCSecondary ossification center associated regulator of chondrocyte maturation. (121 aa)
VWFUncharacterized protein. (2818 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1717 aa)
POSTNPeriostin. (836 aa)
COL4A3Collagen type IV alpha 3 chain. (1669 aa)
COL4A6Collagen type IV alpha 6 chain. (1705 aa)
NTN4Netrin 4. (628 aa)
MATN3Matrilin 3. (484 aa)
VITVitrin. (693 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (963 aa)
ANXA2Annexin. (339 aa)
COL5A1Collagen type V alpha 1 chain. (1837 aa)
ANGPT1Angiopoietin 1. (498 aa)
ENSFCAP00000046833Uncharacterized protein. (300 aa)
MATN4Matrilin 4. (843 aa)
MFAP4Microfibril associated protein 4. (359 aa)
COL4A5Collagen type IV alpha 5 chain. (1689 aa)
FGL1Fibrinogen like 1. (378 aa)
COL10A1Collagen type X alpha 1 chain. (674 aa)
NID2Nidogen 2. (1401 aa)
ABI3BPABI family member 3 binding protein. (1771 aa)
VWC2Von Willebrand factor C domain containing 2. (333 aa)
DAG1Peptidase S72 domain-containing protein. (892 aa)
COL6A5Collagen type VI alpha 5 chain. (2340 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1302 aa)
AMELXAmelogenin X-linked. (205 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (246 aa)
RARRES2Retinoic acid receptor responder 2. (451 aa)
VWA2Von Willebrand factor A domain containing 2. (778 aa)
ENSFCAP00000052562Fibrillar collagen NC1 domain-containing protein. (305 aa)
ELNElastin. (732 aa)
NTN3Netrin 3. (607 aa)
COL5A3Collagen type V alpha 3 chain. (1748 aa)
COL4A2Collagen type IV alpha 2 chain. (1854 aa)
LOC101095538Jacalin-type lectin domain-containing protein. (228 aa)
LAMA2Laminin subunit alpha 2. (3125 aa)
COL17A1Collagen type XVII alpha 1 chain. (1495 aa)
ENSFCAP00000053888Uncharacterized protein. (161 aa)
LAMA4Laminin subunit alpha 4. (1856 aa)
ENSFCAP00000054558annotation not available (662 aa)
CHADLChondroadherin like. (891 aa)
COMPCartilage oligomeric matrix protein. (804 aa)
AGRNAgrin. (2135 aa)
VCANVersican. (3383 aa)
COL25A1Collagen type XXV alpha 1 chain. (693 aa)
COL20A1Collagen type XX alpha 1 chain. (1269 aa)
SSC5DScavenger receptor cysteine rich family member with 5 domains. (1541 aa)
FBLN5Fibulin 5. (491 aa)
ENSFCAP00000057142Uncharacterized protein. (773 aa)
SMOC2SPARC related modular calcium binding 2. (570 aa)
ENSFCAP00000057337Uncharacterized protein. (131 aa)
MMRN2Multimerin 2. (1005 aa)
NTN1Netrin 1. (715 aa)
COL9A2Collagen type IX alpha 2 chain. (722 aa)
HAPLN4Hyaluronan and proteoglycan link protein 4. (442 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (788 aa)
RNASE4Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (189 aa)
ANGPTL1Angiopoietin like 1. (544 aa)
ANGPTL6Angiopoietin like 6. (546 aa)
SPARCL1SPARC like 1. (711 aa)
LAMA5Laminin subunit alpha 5. (3001 aa)
CE1H17orf58Uncharacterized protein. (534 aa)
FIBCD1Fibrinogen C domain containing 1. (461 aa)
NTNG1Netrin G1. (581 aa)
HSPG2Heparan sulfate proteoglycan 2. (4385 aa)
MATN2Matrilin 2. (964 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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