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| FBXW7 | F-box and WD repeat domain containing 7. (749 aa) | ||||
| PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (615 aa) | ||||
| PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (801 aa) | ||||
| CX3CL1 | C-X3-C motif chemokine ligand 1. (449 aa) | ||||
| CCL19 | C-C motif chemokine. (115 aa) | ||||
| ROS1 | Tyrosine-protein kinase receptor. (2309 aa) | ||||
| TNFRSF11A | TNF receptor superfamily member 11a. (638 aa) | ||||
| ENSFCAP00000059689 | Uncharacterized protein. (377 aa) | ||||
| TRAF7 | TNF receptor associated factor 7. (825 aa) | ||||
| ADCYAP1 | Adenylate cyclase activating polypeptide 1. (318 aa) | ||||
| HMGB1 | Uncharacterized protein. (233 aa) | ||||
| VRK3 | VRK serine/threonine kinase 3. (453 aa) | ||||
| PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) | ||||
| PTPRC | Protein tyrosine phosphatase receptor type C. (1299 aa) | ||||
| ENSFCAP00000056245 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (178 aa) | ||||
| ZDHHC17 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (686 aa) | ||||
| WNK2 | WNK lysine deficient protein kinase 2. (2159 aa) | ||||
| RASGRP1 | RAS guanyl releasing protein 1. (877 aa) | ||||
| EZR | Ezrin. (639 aa) | ||||
| PRKCZ | Protein kinase C zeta. (649 aa) | ||||
| GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (362 aa) | ||||
| ANKRD26 | ANK_REP_REGION domain-containing protein. (266 aa) | ||||
| CCN2 | Cellular communication network factor 2. (477 aa) | ||||
| THPO | Thrombopoietin. (409 aa) | ||||
| TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (963 aa) | ||||
| PDGFD | Platelet derived growth factor D. (380 aa) | ||||
| ENSFCAP00000052225 | C-C motif chemokine. (80 aa) | ||||
| C5AR2 | Complement component 5a receptor 2. (332 aa) | ||||
| DENND2B | Suppression of tumorigenicity 5. (1184 aa) | ||||
| FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (170 aa) | ||||
| BMP4 | Bone morphogenetic protein 4. (409 aa) | ||||
| CXCL17 | C-X-C motif chemokine ligand 17. (119 aa) | ||||
| PYCARD | PYD and CARD domain containing. (195 aa) | ||||
| DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) | ||||
| ENSFCAP00000050587 | SCY domain-containing protein. (157 aa) | ||||
| SCIMP | SLP adaptor and CSK interacting membrane protein. (143 aa) | ||||
| FBLN1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa) | ||||
| C3orf33 | Chromosome 3 open reading frame 33. (301 aa) | ||||
| FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa) | ||||
| DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) | ||||
| DLG2 | Discs large MAGUK scaffold protein 2. (1012 aa) | ||||
| PTPRR | Protein tyrosine phosphatase receptor type R. (655 aa) | ||||
| DUSP26 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (219 aa) | ||||
| SYNJ2BP | Synaptojanin 2 binding protein. (145 aa) | ||||
| CD44 | CD44 molecule (Indian blood group). (741 aa) | ||||
| FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa) | ||||
| ALKAL2 | Uncharacterized protein. (60 aa) | ||||
| MFHAS1 | Malignant fibrous histiocytoma amplified sequence 1. (1157 aa) | ||||
| RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1700 aa) | ||||
| ALKAL1 | Uncharacterized protein. (283 aa) | ||||
| FGFR3 | Fibroblast growth factor receptor. (805 aa) | ||||
| GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa) | ||||
| HAND2 | Heart and neural crest derivatives expressed 2. (275 aa) | ||||
| PTPN2 | Tyrosine-protein phosphatase non-receptor type. (416 aa) | ||||
| C1QL4 | Complement C1q like 4. (238 aa) | ||||
| FLCN | Uncharacterized protein. (579 aa) | ||||
| ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) | ||||
| EPHB1 | EPH receptor B1. (984 aa) | ||||
| PHB | Prohibitin. (272 aa) | ||||
| CCL26 | C-C motif chemokine. (94 aa) | ||||
| C5AR1 | Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa) | ||||
| CCL7 | C-C motif chemokine. (99 aa) | ||||
| GAREM2 | GRB2 associated regulator of MAPK1 subtype 2. (869 aa) | ||||
| EGFR | Receptor protein-tyrosine kinase. (1209 aa) | ||||
| RAMP3 | Receptor activity modifying protein 3. (150 aa) | ||||
| LOC100302541 | C-C motif chemokine. (102 aa) | ||||
| SRC | Tyrosine-protein kinase. (678 aa) | ||||
| NDRG4 | NDRG family member 4. (424 aa) | ||||
| FRS2 | Fibroblast growth factor receptor substrate 2. (543 aa) | ||||
| FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) | ||||
| TLR9 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1031 aa) | ||||
| NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) | ||||
| RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1270 aa) | ||||
| CCL22 | C-C motif chemokine. (93 aa) | ||||
| CAVIN3 | Uncharacterized protein. (261 aa) | ||||
| RANBP9 | RAN binding protein 9. (725 aa) | ||||
| DNAJC27 | DnaJ heat shock protein family (Hsp40) member C27. (273 aa) | ||||
| LIF | LIF interleukin 6 family cytokine. (204 aa) | ||||
| MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
| SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa) | ||||
| LOC100302540 | C-C motif chemokine. (93 aa) | ||||
| NPNT | Nephronectin. (612 aa) | ||||
| PSCA | Prostate stem cell antigen. (115 aa) | ||||
| FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
| FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa) | ||||
| FBXW9 | F-box and WD repeat domain containing 9. (458 aa) | ||||
| EPHB2 | EPH receptor B2. (899 aa) | ||||
| CARD9 | Caspase recruitment domain family member 9. (732 aa) | ||||
| SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
| ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (213 aa) | ||||
| BMP2 | Bone morphogenetic protein 2. (395 aa) | ||||
| APELA | Uncharacterized protein. (54 aa) | ||||
| CHI3L1 | Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (383 aa) | ||||
| CCL1 | SCY domain-containing protein. (94 aa) | ||||
| PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
| ENSFCAP00000029786 | Uncharacterized protein. (76 aa) | ||||
| TIMP3 | TIMP metallopeptidase inhibitor 3. (211 aa) | ||||
| HCRTR1 | Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa) | ||||
| GLIPR2 | GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa) | ||||
| DAB2IP | DAB2 interacting protein. (1166 aa) | ||||
| HAVCR2 | Hepatitis A virus cellular receptor 2. (280 aa) | ||||
| OPRM1 | Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (419 aa) | ||||
| STYX | Serine/threonine/tyrosine interacting protein. (223 aa) | ||||
| P2RY6 | Pyrimidinergic receptor P2Y6. (386 aa) | ||||
| HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) | ||||
| SEMA6A | Semaphorin 6A; Belongs to the semaphorin family. (1047 aa) | ||||
| ATF3 | Activating transcription factor 3. (259 aa) | ||||
| NOX4 | NADPH oxidase 4. (578 aa) | ||||
| GPR55 | G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (320 aa) | ||||
| CIB1 | Calcium and integrin binding 1. (191 aa) | ||||
| TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (870 aa) | ||||
| FERMT2 | Fermitin family member 2. (706 aa) | ||||
| PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) | ||||
| DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) | ||||
| ERBB2 | Receptor protein-tyrosine kinase. (1308 aa) | ||||
| CCL13 | C-C motif chemokine. (98 aa) | ||||
| LYN | Tyrosine-protein kinase. (526 aa) | ||||
| RAP1A | RAP1A, member of RAS oncogene family. (184 aa) | ||||
| PHB2 | Prohibitin. (299 aa) | ||||
| LOC101081599 | SCY domain-containing protein. (158 aa) | ||||
| JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) | ||||
| RRAS | RAS related. (218 aa) | ||||
| NOTCH1 | Notch receptor 1. (2543 aa) | ||||
| EMILIN1 | Elastin microfibril interfacer 1. (1025 aa) | ||||
| CCL24 | C-C motif chemokine ligand 24. (119 aa) | ||||
| PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa) | ||||
| CCN1 | Cellular communication network factor 1. (382 aa) | ||||
| NLRP6 | NLR family pyrin domain containing 6. (878 aa) | ||||
| YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa) | ||||
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1. (876 aa) | ||||
| HTR2B | 5-hydroxytryptamine receptor 2B. (503 aa) | ||||
| RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) | ||||
| PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) | ||||
| CCL14 | C-C motif chemokine. (95 aa) | ||||
| FGFR4 | Fibroblast growth factor receptor. (830 aa) | ||||
| PDGFB | Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (245 aa) | ||||
| SLC30A10 | Solute carrier family 30 member 10. (483 aa) | ||||
| DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (477 aa) | ||||
| NDRG2 | NDRG family member 2. (394 aa) | ||||
| SYK | Spleen associated tyrosine kinase. (636 aa) | ||||
| MARCO | Macrophage receptor with collagenous structure. (486 aa) | ||||
| ADIPOQ | Adiponectin, C1Q and collagen domain containing. (283 aa) | ||||
| CCL8 | C-C motif chemokine. (99 aa) | ||||
| SPRY1 | Sprouty RTK signaling antagonist 1. (362 aa) | ||||
| FGB | Fibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (473 aa) | ||||
| TNIP1 | TNFAIP3 interacting protein 1. (635 aa) | ||||
| BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) | ||||
| MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa) | ||||
| ACKR3 | Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (406 aa) | ||||
| SPRED1 | Sprouty related EVH1 domain containing 1. (443 aa) | ||||
| PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa) | ||||
| TNIP3 | TNFAIP3 interacting protein 3. (397 aa) | ||||
| IL26 | Interleukin 26. (171 aa) | ||||
| PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (885 aa) | ||||
| EPHA2 | EPH receptor A2. (936 aa) | ||||
| CCL16 | C-C motif chemokine. (107 aa) | ||||
| FFAR4 | G protein coupled receptor 120 / free fatty acid receptor 4. (361 aa) | ||||
| KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1514 aa) | ||||
| NOTCH2 | Notch receptor 2. (2493 aa) | ||||
| PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) | ||||
| PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4078 aa) | ||||
| FN1 | Fibronectin 1. (2475 aa) | ||||
| PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) | ||||
| NOD2 | Nucleotide binding oligomerization domain containing 2. (1014 aa) | ||||
| SEMA7A | Semaphorin 7A; Belongs to the semaphorin family. (769 aa) | ||||
| SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) | ||||
| EPHA4 | EPH receptor A4. (986 aa) | ||||
| FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
| GAS6 | Growth arrest specific 6. (674 aa) | ||||
| DSTYK | Dual serine/threonine and tyrosine protein kinase. (929 aa) | ||||
| NPTN | Neuroplastin. (446 aa) | ||||
| SERPINF2 | Serpin family F member 2; Belongs to the serpin family. (565 aa) | ||||
| CRKL | CRK like proto-oncogene, adaptor protein. (342 aa) | ||||
| TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa) | ||||
| IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) | ||||
| DUPD1 | Dual specificity phosphatase and pro isomerase domain containing 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (321 aa) | ||||
| TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
| ABL1 | Tyrosine-protein kinase. (1150 aa) | ||||
| PLA2G5 | Phospholipase A(2). (158 aa) | ||||
| CCL17 | C-C motif chemokine 17; Chemotactic factor for t lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4 and CCR8 (By similarity). (99 aa) | ||||
| AGER | Advanced glycosylation end-product specific receptor. (492 aa) | ||||
| CD4 | CD4 molecule. (487 aa) | ||||
| DUSP9 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (380 aa) | ||||
| PTPN1 | Tyrosine-protein phosphatase non-receptor type. (427 aa) | ||||
| SLAMF1 | Signaling lymphocytic activation molecule family member 1. (347 aa) | ||||
| PRXL2C | Peroxiredoxin like 2C. (232 aa) | ||||
| SPRY4 | Sprouty RTK signaling antagonist 4. (321 aa) | ||||
| PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1131 aa) | ||||
| CSF1R | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulat [...] (1213 aa) | ||||
| CCL20 | C-C motif chemokine. (97 aa) | ||||
| F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa) | ||||
| CCL21 | C-C motif chemokine ligand 21. (134 aa) | ||||
| NEK10 | NIMA related kinase 10. (1173 aa) | ||||
| TEK | TEK receptor tyrosine kinase. (1125 aa) | ||||
| TREM2 | Triggering receptor expressed on myeloid cells 2. (258 aa) | ||||
| APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa) | ||||
| FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1405 aa) | ||||
| APP | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (935 aa) | ||||
| SHC1 | SHC adaptor protein 1. (566 aa) | ||||
| CCL5 | C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family. (91 aa) | ||||
| NODAL | Nodal growth differentiation factor. (348 aa) | ||||
| FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (692 aa) | ||||
| BMPER | BMP binding endothelial regulator. (685 aa) | ||||