STRINGSTRING
IL1B IL1B S100A9 S100A9 S100A8 S100A8 STK10 STK10 SEMA4D SEMA4D RAC2 RAC2 RAC3 RAC3 CD44 CD44 JAM2 JAM2 MSN MSN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa)
S100A9Protein S100; Belongs to the S-100 family. (135 aa)
S100A8Protein S100; Belongs to the S-100 family. (124 aa)
STK10Serine/threonine kinase 10. (967 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (863 aa)
RAC2Rac family small GTPase 2. (234 aa)
RAC3Rac family small GTPase 3. (205 aa)
CD44CD44 molecule (Indian blood group). (741 aa)
JAM2Junctional adhesion molecule 2. (298 aa)
MSNMoesin. (577 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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