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| | M3WDH2_FELCA | Uncharacterized protein. (157 aa) |
| | TELO2 | Telomere maintenance 2. (824 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (724 aa) |
| | FAM20A | FAM20A golgi associated secretory pathway pseudokinase. (537 aa) |
| | MAP3K10 | Mitogen-activated protein kinase kinase kinase. (937 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1599 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1299 aa) |
| | MTCP1 | Mature T cell proliferation 1. (117 aa) |
| | ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1522 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | CEMIP | Cell migration inducing hyaluronidase 1. (1397 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4299 aa) |
| | PSRC1 | Proline and serine rich coiled-coil 1. (407 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (904 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (638 aa) |
| | SPATC1 | Spermatogenesis and centriole associated 1. (464 aa) |
| | CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (260 aa) |
| | IGF2 | Insulin like growth factor 2. (280 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | ALS2 | Alsin Rho guanine nucleotide exchange factor ALS2. (1650 aa) |
| | ENSFCAP00000037196 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (56 aa) |
| | TLR9 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1031 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (872 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (588 aa) |
| | DAZAP2 | DAZ associated protein 2. (207 aa) |
| | PARP16 | Poly [ADP-ribose] polymerase. (323 aa) |
| | EPGN | Epithelial mitogen. (153 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (353 aa) |
| | TGFA | Transforming growth factor alpha. (192 aa) |
| | SRC | Tyrosine-protein kinase. (678 aa) |
| | CCL19 | C-C motif chemokine. (115 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | CCNK | Cyclin K; Belongs to the cyclin family. (582 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | HMGA2 | Uncharacterized protein. (109 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1225 aa) |
| | CDK5R2 | Cyclin-dependent kinase 5 activator. (370 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1700 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (735 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | CCNT1 | CYCLIN domain-containing protein; Belongs to the cyclin family. (184 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa) |
| | DBF4B | DBF4-type domain-containing protein. (307 aa) |
| | ENSFCAP00000048496 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (62 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (450 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (312 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (170 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (1021 aa) |
| | INCENP | Inner centromere protein. (937 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (796 aa) |
| | PDGFD | Platelet derived growth factor D. (380 aa) |
| | DRD4 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (595 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (877 aa) |
| | LOC102901812 | Uncharacterized protein. (283 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (742 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | MAPRE3 | Microtubule associated protein RP/EB family member 3. (281 aa) |
| | ENSFCAP00000031202 | Uncharacterized protein. (94 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1381 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1275 aa) |
| | ENSFCAP00000030418 | KH type-2 domain-containing protein. (147 aa) |
| | ENSFCAP00000030239 | Uncharacterized protein. (145 aa) |
| | DAB2IP | DAB2 interacting protein. (1166 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (927 aa) |
| | SIRT1 | Sirtuin 1. (745 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | FGD2 | FYVE, RhoGEF and PH domain containing 2. (656 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (970 aa) |
| | STRADB | STE20 related adaptor beta. (415 aa) |
| | CAB39 | Calcium binding protein 39. (373 aa) |
| | NOX4 | NADPH oxidase 4. (578 aa) |
| | IL34 | Interleukin 34. (331 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | CCNY | Cyclin Y; Belongs to the cyclin family. (341 aa) |
| | CIB1 | Calcium and integrin binding 1. (191 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (870 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa) |
| | FERMT2 | Fermitin family member 2. (706 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | TAOK3 | TAO kinase 3. (914 aa) |
| | DIPK2A | Divergent protein kinase domain 2A. (430 aa) |
| | DBF4 | DBF4 zinc finger. (676 aa) |
| | ETAA1 | ETAA1 activator of ATR kinase. (929 aa) |
| | SPDYA | Speedy/RINGO cell cycle regulator family member A. (309 aa) |
| | RALB | RAS like proto-oncogene B. (206 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (662 aa) |
| | SYAP1 | Synapse associated protein 1. (358 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (865 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | CCNYL1 | Cyclin Y like 1; Belongs to the cyclin family. (363 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | M3WSW9_FELCA | Uncharacterized protein. (162 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (503 aa) |
| | SPDYC | Speedy/RINGO cell cycle regulator family member C. (243 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | TCL1B | T cell leukemia/lymphoma 1B. (130 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (245 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (863 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa) |
| | SPATC1L | Spermatogenesis and centriole associated 1 like. (343 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (747 aa) |
| | CAB39L | Calcium binding protein 39 like. (193 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | CAMK1 | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (283 aa) |
| | TCIM | Transcriptional and immune response regulator. (107 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa) |
| | MAP4K2 | Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | LOC101099765 | Uncharacterized protein. (226 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (979 aa) |
| | NEK10 | NIMA related kinase 10. (1173 aa) |
| | STRADA | STE20 related adaptor alpha. (431 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (972 aa) |
| | CSF1R | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulat [...] (1213 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (427 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (492 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | ACSL1 | Acyl-CoA synthetase long chain family member 1. (698 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa) |
| | AJUBA | Ajuba LIM protein. (548 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (718 aa) |
| | ADRB2 | Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1014 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (460 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa) |
| | C1QTNF9 | Adiponectin F1. (332 aa) |
