STRINGSTRING
HRK HRK PYCARD PYCARD TNFSF10 TNFSF10 BID BID BIK BIK BAK1 BAK1 FAM162A FAM162A NOL3 NOL3 BNIP3 BNIP3 PRELID1 PRELID1 PINK1 PINK1 BAX BAX PARL PARL PDCD5 PDCD5 PLAUR PLAUR PLSCR3 PLSCR3 LMNA LMNA MLLT11 MLLT11 M3WWT0_FELCA M3WWT0_FELCA CIDEB CIDEB PSMD10 PSMD10 FXN FXN PPIF PPIF GHITM GHITM AVP AVP HGF HGF IGF1 IGF1 PRKN PRKN GPER1 GPER1 TP53 TP53 BBC3 BBC3 ENSFCAP00000047489 ENSFCAP00000047489 BAD BAD OPA1 OPA1 PMAIP1 PMAIP1 BCL2L11 BCL2L11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HRKActivator of apoptosis harakiri; Promotes apoptosis. (91 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TNFSF10TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (347 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (205 aa)
BIKUncharacterized protein. (245 aa)
BAK1BCL2 antagonist/killer 1. (251 aa)
FAM162AFamily with sequence similarity 162 member A. (167 aa)
NOL3Nucleolar protein 3. (218 aa)
BNIP3BCL2 interacting protein 3. (187 aa)
PRELID1PRELI domain containing 1. (219 aa)
PINK1PTEN induced kinase 1. (581 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
PARLRhomboid domain-containing protein. (379 aa)
PDCD5Programmed cell death 5. (197 aa)
PLAURPlasminogen activator, urokinase receptor. (335 aa)
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (295 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
MLLT11MLLT11 transcription factor 7 cofactor. (90 aa)
M3WWT0_FELCARhomboid domain-containing protein. (188 aa)
CIDEBCell death inducing DFFA like effector b. (221 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
FXNFrataxin. (211 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (204 aa)
GHITMGrowth hormone inducible transmembrane protein; Belongs to the BI1 family. (345 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (166 aa)
HGFHepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity). (728 aa)
IGF1Insulin like growth factor 1. (195 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
BBC3Uncharacterized protein. (193 aa)
ENSFCAP00000047489Uncharacterized protein; Belongs to the BI1 family. (200 aa)
BADBCL2 associated agonist of cell death. (273 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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