STRINGSTRING
NEDD9 NEDD9 NRP1 NRP1 CRKL CRKL UNC13D UNC13D ABL1 ABL1 CDC42 CDC42 PREX1 PREX1 MELTF MELTF SPRY4 SPRY4 CORO1C CORO1C ACTN4 ACTN4 ENSFCAP00000027204 ENSFCAP00000027204 CASS4 CASS4 ITGB1BP1 ITGB1BP1 MYOC MYOC ITGB3 ITGB3 FLNA FLNA LIMS2 LIMS2 EFNA5 EFNA5 RCC2 RCC2 DMTN DMTN KANK1 KANK1 C1QBP C1QBP ENSFCAP00000057420 ENSFCAP00000057420 CARMIL1 CARMIL1 FBLN1 FBLN1 LIMS1 LIMS1 S100A10 S100A10 LRRC45 LRRC45 BRAF BRAF ILK ILK AP1AR AP1AR MYADM MYADM TESK1 TESK1 TRIOBP TRIOBP PDPN PDPN RREB1 RREB1 FERMT2 FERMT2 CIB1 CIB1 P4HB P4HB CRK CRK CDC42-2 CDC42-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (835 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
CRKLCRK like proto-oncogene, adaptor protein. (342 aa)
UNC13DUnc-13 homolog D. (1091 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
CDC42Uncharacterized protein. (191 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1647 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (744 aa)
SPRY4Sprouty RTK signaling antagonist 4. (321 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)
ACTN4Actinin alpha 4. (933 aa)
ENSFCAP00000027204Uncharacterized protein. (119 aa)
CASS4Cas scaffold protein family member 4. (818 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (213 aa)
MYOCMyocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...] (498 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
FLNAFilamin A. (2808 aa)
LIMS2LIM zinc finger domain containing 2. (467 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
RCC2Regulator of chromosome condensation 2. (522 aa)
DMTNDematin actin binding protein. (405 aa)
KANK1KN motif and ankyrin repeat domains 1. (1366 aa)
C1QBPComplement C1q binding protein. (314 aa)
ENSFCAP00000057420Uncharacterized protein. (443 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1420 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (804 aa)
ILKIntegrin linked kinase. (451 aa)
AP1ARAdaptor related protein complex 1 associated regulatory protein. (302 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
TESK1Testis associated actin remodelling kinase 1. (628 aa)
TRIOBPPH domain-containing protein. (908 aa)
PDPNPodoplanin. (163 aa)
RREB1Ras responsive element binding protein 1. (1765 aa)
FERMT2Fermitin family member 2. (706 aa)
CIB1Calcium and integrin binding 1. (191 aa)
P4HBProtein disulfide-isomerase. (510 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
CDC42-2Uncharacterized protein. (191 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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