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| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1036 aa) |
| | CSRP3 | Cysteine and glycine rich protein 3. (271 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | PHIP | Pleckstrin homology domain interacting protein. (1821 aa) |
| | TYK2 | Tyrosine-protein kinase. (1181 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (700 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1014 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | ADRB2 | Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa) |
| | LGMN | Legumain. (433 aa) |
| | SLC24A4 | Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa) |
| | BCAR3 | BCAR3 adaptor protein, NSP family member. (935 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1181 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1208 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1. (598 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | AGTR1 | Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (393 aa) |
| | IRS4 | Insulin receptor substrate 4. (1251 aa) |
| | IRF5 | Interferon regulatory factor 5. (504 aa) |
| | SHC1 | SHC adaptor protein 1. (566 aa) |
| | SLC39A14 | Solute carrier family 39 member 14. (491 aa) |
| | APP | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (935 aa) |
| | GLP2R | Glucagon like peptide 2 receptor. (373 aa) |
| | DENND4C | DENN domain containing 4C. (1957 aa) |
| | JAK1 | Tyrosine-protein kinase. (1157 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (558 aa) |
| | STAT5B | Signal transducer and activator of transcription. (786 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | GHRHR | Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa) |
| | EPRS1 | Glutamyl-prolyl-tRNA synthetase. (1576 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | JAK3 | Tyrosine-protein kinase. (1232 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (258 aa) |
| | MAS1 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (585 aa) |
| | DNAI1 | Dynein axonemal intermediate chain 1. (719 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (594 aa) |
| | GH1 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (246 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PRKCD | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (427 aa) |
| | KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (492 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | AHCYL1 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | INHBB | Inhibin subunit beta B. (407 aa) |
| | LOC101082144 | C-type lectin domain-containing protein. (176 aa) |
| | LPIN3 | Lipin 3. (1036 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) |
| | GLP1R | Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (454 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (979 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | GSK3A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | ZDHHC7 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa) |
| | TRIM16 | Uncharacterized protein. (528 aa) |
| | LOC101100432 | Uncharacterized protein. (514 aa) |
| | RAB8B | RAB8B, member RAS oncogene family. (207 aa) |
| | SLC2A8 | Solute carrier family 2 member 8. (315 aa) |
| | NOTCH1 | Notch receptor 1. (2543 aa) |
| | PARP6 | Poly [ADP-ribose] polymerase. (630 aa) |
| | CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (262 aa) |
| | SYAP1 | Synapse associated protein 1. (358 aa) |
| | IRS1 | Insulin receptor substrate 1. (1234 aa) |
| | RAB12 | RAB12, member RAS oncogene family. (339 aa) |
| | RUSC1 | RUN and SH3 domain containing 1. (907 aa) |
| | LDOC1 | LDOC1 regulator of NFKB signaling. (146 aa) |
| | PDK4 | Protein-serine/threonine kinase. (412 aa) |
| | INSRR | Tyrosine-protein kinase receptor. (1300 aa) |
| | LOC101081229 | Pyruvate kinase; Belongs to the pyruvate kinase family. (353 aa) |
| | ZBTB7B | Uncharacterized protein. (540 aa) |
| | STXBP3 | Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | LPIN2 | Lipin 2. (936 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | TBC1D4 | TBC1 domain family member 4. (1297 aa) |
| | GCGR | Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (484 aa) |
| | OTOP1 | Otopetrin 1. (607 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1104 aa) |
| | SCAP | SREBF chaperone. (1278 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa) |
| | EPM2AIP1 | EPM2A interacting protein 1. (608 aa) |
| | CRHR2 | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (437 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (614 aa) |
| | PRLH | Prolactin releasing hormone. (83 aa) |
| | TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. (770 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | SIRT1 | Sirtuin 1. (745 aa) |
| | ERBIN | Erbb2 interacting protein. (1461 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (1208 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (692 aa) |
| | CACNB1 | Calcium voltage-gated channel auxiliary subunit beta 1. (702 aa) |
| | KHK | Ketohexokinase. (298 aa) |
| | SH2B2 | SH2B adaptor protein 2. (679 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (634 aa) |
| | ENSFCAP00000044386 | Uncharacterized protein. (156 aa) |
| | NGFR | Nerve growth factor receptor. (421 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | GSK3B | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase regulatory subunit 2. (726 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (416 aa) |
| | TSC1 | TSC complex subunit 1. (1110 aa) |
| | ENSFCAP00000042577 | DUF4939 domain-containing protein. (113 aa) |
| | TGFBR3L | ZP domain-containing protein. (485 aa) |
| | PKM | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (By similarity). Stimulates POU5F1-mediated transcriptional activation (By similarity). Promotes in a STAT1-dependent manner, the expression of the immune checkpoint protein CD274 in ARNTL/BMAL1-deficient macrophages (By similarity). (531 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2498 aa) |
| | XBP1 | X-box binding protein 1. (383 aa) |
| | RAMP3 | Receptor activity modifying protein 3. (150 aa) |
| | CRHR1 | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (426 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (400 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | IRS2 | Insulin receptor substrate 2. (1335 aa) |
| | SRC | Tyrosine-protein kinase. (678 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (712 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (587 aa) |
| | STXBP4 | Uncharacterized protein. (562 aa) |
| | C2CD5 | C2 calcium dependent domain containing 5. (1126 aa) |
| | ZNF106 | Zinc finger protein 106. (1902 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (372 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (651 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) |
| | CSN1S1 | Casein alpha s1. (183 aa) |
| | MGARP | Mitochondria localized glutamic acid rich protein. (241 aa) |
| | ENSFCAP00000049367 | annotation not available (113 aa) |
| | JAK2 | Tyrosine-protein kinase. (1131 aa) |
| | ACTN2 | Actinin alpha 2. (910 aa) |
| | SESN3 | Sestrin 3. (492 aa) |
| | LOC101097790 | Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | RAB13 | Uncharacterized protein. (203 aa) |
| | STAT1 | Signal transducer and activator of transcription. (885 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | RAB15 | Uncharacterized protein. (425 aa) |
| | ZBED3 | Zinc finger BED-type containing 3. (236 aa) |
| | RARRES2 | Retinoic acid receptor responder 2. (451 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (796 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (963 aa) |
| | ENSFCAP00000053190 | DUF4371 domain-containing protein. (595 aa) |
| | RAB10 | RAB10, member RAS oncogene family. (200 aa) |
| | CAPN10 | Calpain 10; Belongs to the peptidase C2 family. (725 aa) |
| | VGF | VGF nerve growth factor inducible. (616 aa) |
| | TRARG1 | Trafficking regulator of GLUT4 (SLC2A4) 1. (177 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa) |
| | RHOQ | Ras homolog family member Q. (214 aa) |
| | CEP170 | Centrosomal protein 170. (1588 aa) |
| | LPIN1 | Lipin 1. (976 aa) |
| | KBTBD2 | Kelch repeat and BTB domain containing 2. (623 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (357 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa) |
| | RAB31 | RAB31, member RAS oncogene family. (210 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2202 aa) |
| | ANKRD26 | ANK_REP_REGION domain-containing protein. (266 aa) |
| | INAVA | Innate immunity activator. (656 aa) |
| | NDEL1 | NudE neurodevelopment protein 1 like 1. (480 aa) |
| | EIF4EBP2 | Eukaryotic translation initiation factor 4E binding protein 2. (142 aa) |
| | CA2 | Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (263 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | USF1 | Upstream transcription factor 1. (444 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | LOC102900614 | Uncharacterized protein. (594 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (804 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1287 aa) |
| | SLC27A4 | Solute carrier family 27 member 4. (691 aa) |
| | GRB14 | Growth factor receptor bound protein 14. (717 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (571 aa) |
| | INPP5K | Inositol polyphosphate-5-phosphatase K. (525 aa) |
| | ANXA1 | Annexin. (407 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (674 aa) |
| | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (1027 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (700 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (801 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1381 aa) |
| | PRNP | Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (260 aa) |
| | IGFBP2 | Insulin like growth factor binding protein 2. (330 aa) |
| | NCOA5 | Nuclear receptor coactivator 5. (544 aa) |
| | IGFBP5 | Insulin like growth factor binding protein 5. (282 aa) |
| | FOXO4 | Forkhead box O4. (515 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (732 aa) |
| | PTPRA | Receptor-type tyrosine-protein phosphatase alpha. (826 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | CRADD | Uncharacterized protein. (398 aa) |
| | APC | APC regulator of WNT signaling pathway. (2874 aa) |
| | FOXO1 | Forkhead box O1. (662 aa) |
| | UMODL1 | Uromodulin like 1. (1281 aa) |
| | RB1 | RB transcriptional corepressor 1. (930 aa) |
| | VPS13C | Vacuolar protein sorting 13 homolog C. (3752 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (870 aa) |
| | CPEB2 | Cytoplasmic polyadenylation element binding protein 2. (1045 aa) |
| | IGFBP3 | Insulin like growth factor binding protein 3. (299 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (620 aa) |
| | LOC101081885 | C-type lectin domain-containing protein. (176 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (221 aa) |
| | SORT1 | Sortilin. (877 aa) |
| | SLC30A10 | Solute carrier family 30 member 10. (483 aa) |
| | HADHA | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (1466 aa) |
| | STAT6 | Signal transducer and activator of transcription. (844 aa) |
| | AGTR2 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (283 aa) |
| | SOGA1 | Suppressor of glucose, autophagy associated 1. (1657 aa) |
| | GRB10 | Growth factor receptor bound protein 10. (594 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (828 aa) |
| | TIMELESS | Timeless circadian regulator. (1211 aa) |
| | STAT2 | Signal transducer and activator of transcription. (855 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (873 aa) |
