85 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TIMM44	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (454 aa)
	SFXN3	Sidoreflexin. (325 aa)
	MICU3	Mitochondrial calcium uptake family member 3. (531 aa)
	SLC25A3	Solute carrier family 25 member 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (377 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
	SLC25A33	Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
	TOMM70	Translocase of outer mitochondrial membrane 70. (609 aa)
	M3X1Q0_FELCA	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (334 aa)
	M3X1T3_FELCA	CHCH domain-containing protein. (146 aa)
	TIMM21	Translocase of inner mitochondrial membrane 21. (244 aa)
	TOMM20	Translocase of outer mitochondrial membrane 20. (145 aa)
	MPC1L	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (145 aa)
	SLC25A53	Solute carrier family 25 member 53; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa)
	SLC25A41	Solute carrier family 25 member 41; Belongs to the mitochondrial carrier (TC 2.A.29) family. (368 aa)
	M3XE36_FELCA	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (243 aa)
	SLC25A28	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family. (364 aa)
	ENSFCAP00000040280	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (127 aa)
	GRPEL2	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (380 aa)
	MICU1	Mitochondrial calcium uptake 1. (484 aa)
	TOMM7	Translocase of outer mitochondrial membrane 7. (55 aa)
	ENSFCAP00000039745	Uncharacterized protein. (55 aa)
	SLC25A12	Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (693 aa)
	LOC101094135	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (209 aa)
	SLC25A29	Solute carrier family 25 member 29; Belongs to the mitochondrial carrier (TC 2.A.29) family. (406 aa)
	SLC25A4	Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	TOMM40L	Translocase of outer mitochondrial membrane 40 like. (324 aa)
	SLC25A40	Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (339 aa)
	SLC25A39	Solute carrier family 25 member 39; Belongs to the mitochondrial carrier (TC 2.A.29) family. (359 aa)
	DNAJC15	DnaJ heat shock protein family (Hsp40) member C15. (149 aa)
	NECTIN2	Nectin cell adhesion molecule 2. (539 aa)
	ENSFCAP00000025816	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (145 aa)
	C3orf18	Chromosome 3 open reading frame 18. (182 aa)
	TIMM50	Translocase of inner mitochondrial membrane 50. (608 aa)
	SMDT1	Single-pass membrane protein with aspartate rich tail 1. (107 aa)
	SLC25A21	Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family. (319 aa)
	TST	Sulfurtransferase. (559 aa)
	TIMM17B	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (172 aa)
	SLC25A38	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (302 aa)
	MRPL18	Mitochondrial ribosomal protein L18. (180 aa)
	ROMO1	Reactive oxygen species modulator 1. (79 aa)
	UCP2	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
	SLC25A37	Solute carrier family 25 member 37; Belongs to the mitochondrial carrier (TC 2.A.29) family. (342 aa)
	MCUR1	Mitochondrial calcium uniporter regulator 1. (371 aa)
	SLC25A5	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	SLC25A31	Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
	AIFM1	Apoptosis inducing factor mitochondria associated 1. (613 aa)
	UCP1	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	SLC25A1	Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
	ABCB7	ATP binding cassette subfamily B member 7. (752 aa)
	LETM1	Leucine zipper and EF-hand containing transmembrane protein 1. (739 aa)
	SFXN5	Sidoreflexin. (347 aa)
	SLC25A13	Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (676 aa)
	SLC39A8	Solute carrier family 39 member 8. (461 aa)
	ABCB8	ATP binding cassette subfamily B member 8. (713 aa)
	PNPT1	Polyribonucleotide nucleotidyltransferase 1. (784 aa)
	SLC25A22	Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (469 aa)
	SLC25A15	Solute carrier family 25 member 15; Belongs to the mitochondrial carrier (TC 2.A.29) family. (331 aa)
	ENSFCAP00000058976	Uncharacterized protein. (105 aa)
	STOML2	Stomatin like 2. (425 aa)
	SFXN4	Sideroflexin 4. (385 aa)
	TIMM17A	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (208 aa)
	SLC25A32	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (400 aa)
	SLC25A51	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (272 aa)
	LOC111558717	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
	SLC25A18	Solute carrier family 25 member 18; Belongs to the mitochondrial carrier (TC 2.A.29) family. (341 aa)
	SLC8B1	Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (653 aa)
	MICU2	Mitochondrial calcium uptake 2. (470 aa)
	MCU	Mitochondrial calcium uniporter. (475 aa)
	DNAJC19	Uncharacterized protein. (144 aa)
	CHCHD4	CHCH domain-containing protein. (141 aa)
	MPC1	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (109 aa)
	MRS2	Magnesium transporter. (464 aa)
	TOMM20L	Translocase of outer mitochondrial membrane 20 like. (152 aa)
	SLC41A3	Solute carrier family 41 member 3. (481 aa)
	SLC25A6	Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
	GRPEL1	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
	ENSFCAP00000048291	Uncharacterized protein. (113 aa)
	TOMM40	Translocase of outer mitochondrial membrane 40. (361 aa)
	SLC25A36	Solute carrier family 25 member 36; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
	SFXN1	Sidoreflexin. (337 aa)
	MCUB	Mitochondrial calcium uniporter dominant negative beta subunit. (371 aa)
	ENSFCAP00000043380	Uncharacterized protein. (75 aa)
	SLC25A2	Solute carrier family 25 member 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
	MPC2	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (213 aa)
	CCDC51	Coiled-coil domain containing 51. (409 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB7	ABCB8	ENSFCAP00000008865	ENSFCAP00000012238	ATP binding cassette subfamily B member 7.	ATP binding cassette subfamily B member 8.	0.842
ABCB7	LETM1	ENSFCAP00000008865	ENSFCAP00000009856	ATP binding cassette subfamily B member 7.	Leucine zipper and EF-hand containing transmembrane protein 1.	0.439
ABCB7	SLC25A28	ENSFCAP00000008865	ENSFCAP00000040951	ATP binding cassette subfamily B member 7.	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.537
ABCB7	SLC25A37	ENSFCAP00000008865	ENSFCAP00000005024	ATP binding cassette subfamily B member 7.	Solute carrier family 25 member 37; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.535
ABCB7	SLC25A38	ENSFCAP00000008865	ENSFCAP00000002516	ATP binding cassette subfamily B member 7.	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.	0.733
ABCB7	SLC25A39	ENSFCAP00000008865	ENSFCAP00000030070	ATP binding cassette subfamily B member 7.	Solute carrier family 25 member 39; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.456
ABCB7	TIMM44	ENSFCAP00000008865	ENSFCAP00000013865	ATP binding cassette subfamily B member 7.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.524
ABCB8	ABCB7	ENSFCAP00000012238	ENSFCAP00000008865	ATP binding cassette subfamily B member 8.	ATP binding cassette subfamily B member 7.	0.842
ABCB8	CCDC51	ENSFCAP00000012238	ENSFCAP00000013421	ATP binding cassette subfamily B member 8.	Coiled-coil domain containing 51.	0.639
ABCB8	SLC25A28	ENSFCAP00000012238	ENSFCAP00000040951	ATP binding cassette subfamily B member 8.	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.444
C3orf18	GRPEL1	ENSFCAP00000061624	ENSFCAP00000048386	Chromosome 3 open reading frame 18.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.484
C3orf18	GRPEL2	ENSFCAP00000061624	ENSFCAP00000040172	Chromosome 3 open reading frame 18.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.484
C3orf18	LOC101094135	ENSFCAP00000061624	ENSFCAP00000039404	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.711
C3orf18	TIMM17A	ENSFCAP00000061624	ENSFCAP00000057398	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.535
C3orf18	TIMM17B	ENSFCAP00000061624	ENSFCAP00000002367	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.535
C3orf18	TIMM21	ENSFCAP00000061624	ENSFCAP00000020805	Chromosome 3 open reading frame 18.	Translocase of inner mitochondrial membrane 21.	0.526
C3orf18	TIMM44	ENSFCAP00000061624	ENSFCAP00000013865	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.699
C3orf18	TIMM50	ENSFCAP00000061624	ENSFCAP00000061154	Chromosome 3 open reading frame 18.	Translocase of inner mitochondrial membrane 50.	0.506
CCDC51	ABCB8	ENSFCAP00000013421	ENSFCAP00000012238	Coiled-coil domain containing 51.	ATP binding cassette subfamily B member 8.	0.639
CHCHD4	MICU2	ENSFCAP00000051252	ENSFCAP00000052508	CHCH domain-containing protein.	Mitochondrial calcium uptake 2.	0.411