STRINGSTRING
PRKCD PRKCD MAS1 MAS1 AGTR1 AGTR1 CA2 CA2 ACTN2 ACTN2 RELA RELA SRC SRC ROCK1 ROCK1 CAV1 CAV1 SLC30A10 SLC30A10 COL3A1 COL3A1 AGTR2 AGTR2 AHCYL1 AHCYL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (393 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (263 aa)
ACTN2Actinin alpha 2. (910 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
SRCTyrosine-protein kinase. (678 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
SLC30A10Solute carrier family 30 member 10. (483 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (362 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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