STRINGSTRING
DNAJC11 DNAJC11 LRRK2 LRRK2 SOX10 SOX10 TOMM22 TOMM22 MFSD11 MFSD11 HKDC1 HKDC1 HK1 HK1 ACSL1 ACSL1 RHOT2 RHOT2 HK2 HK2 GDAP1L1 GDAP1L1 USP30 USP30 RAB38 RAB38 GPAT2 GPAT2 SPATA19 SPATA19 VAT1 VAT1 GDAP1 GDAP1 PNPLA3 PNPLA3 TAZ TAZ MTCH2 MTCH2 TOMM70 TOMM70 FUNDC2 FUNDC2 TOMM20 TOMM20 ATF2 ATF2 CISD2 CISD2 KMO KMO BNIP3L BNIP3L NECTIN2 NECTIN2 FUNDC1 FUNDC1 ENSFCAP00000026617 ENSFCAP00000026617 MIEF2 MIEF2 MFN2 MFN2 MTX3 MTX3 SPART SPART TOMM6 TOMM6 MARCHF5 MARCHF5 ARMC12 ARMC12 PLD6 PLD6 CPT1B CPT1B PI4KB PI4KB ENSFCAP00000031232 ENSFCAP00000031232 MFN1 MFN1 MYOC MYOC SPIRE1 SPIRE1 TOMM40L TOMM40L ENSFCAP00000033718 ENSFCAP00000033718 PGRMC1 PGRMC1 TOMM5 TOMM5 CISD1 CISD1 ARMC1 ARMC1 HAX1 HAX1 TOMM7 TOMM7 FIS1 FIS1 LOC111558941 LOC111558941 TMEM205 TMEM205 BCL2L2 BCL2L2 RHOT1 RHOT1 FAM210B FAM210B MTX2 MTX2 MAOA MAOA TOMM40 TOMM40 BAD BAD SYNJ2BP SYNJ2BP SAMD15 SAMD15 MGARP MGARP TIGAR TIGAR TOMM20L TOMM20L GPAM GPAM TOMM34 TOMM34 CPT1A CPT1A BID BID ENSFCAP00000056164 ENSFCAP00000056164 MFF MFF SPATA18 SPATA18 MSTO1 MSTO1 ENSFCAP00000059861 ENSFCAP00000059861 MUL1 MUL1 ENSFCAP00000060319 ENSFCAP00000060319 LOC101083598 LOC101083598 BNIP3 BNIP3 BCL2 BCL2 MTX1 MTX1 RTN4IP1 RTN4IP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNAJC11DnaJ heat shock protein family (Hsp40) member C11. (559 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
SOX10SRY-box transcription factor 10. (604 aa)
TOMM22Translocase of outer mitochondrial membrane 22. (142 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
HK1Hexokinase 1. (1056 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
RHOT2Ras homolog family member T2. (722 aa)
HK2Hexokinase 2. (917 aa)
GDAP1L1Ganglioside induced differentiation associated protein 1 like 1. (367 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (519 aa)
RAB38RAB38, member RAS oncogene family. (211 aa)
GPAT2Glycerol-3-phosphate acyltransferase 2, mitochondrial. (868 aa)
SPATA19Spermatogenesis associated 19. (154 aa)
VAT1Vesicle amine transport 1. (391 aa)
GDAP1Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
PNPLA3Uncharacterized protein. (919 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (262 aa)
MTCH2Mitochondrial carrier 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (303 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (609 aa)
FUNDC2FUN14 domain containing 2. (190 aa)
TOMM20Translocase of outer mitochondrial membrane 20. (145 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
CISD2CDGSH iron sulfur domain 2. (135 aa)
KMOKynurenine 3-monooxygenase. (453 aa)
BNIP3LBCL2 interacting protein 3 like. (219 aa)
NECTIN2Nectin cell adhesion molecule 2. (539 aa)
FUNDC1Uncharacterized protein. (155 aa)
ENSFCAP00000026617Ubiquitin-like domain-containing protein. (78 aa)
MIEF2Mitochondrial elongation factor 2. (453 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
MTX3Metaxin. (312 aa)
SPARTSpartin. (672 aa)
TOMM6Translocase of outer mitochondrial membrane 6. (74 aa)
MARCHF5Membrane associated ring-CH-type finger 5. (278 aa)
ARMC12Armadillo repeat containing 12. (367 aa)
PLD6Phospholipase D family member 6. (229 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (861 aa)
ENSFCAP00000031232Uncharacterized protein. (108 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (804 aa)
MYOCMyocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...] (498 aa)
SPIRE1Spire type actin nucleation factor 1. (810 aa)
TOMM40LTranslocase of outer mitochondrial membrane 40 like. (324 aa)
ENSFCAP00000033718ZnF_CDGSH domain-containing protein. (99 aa)
PGRMC1Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (195 aa)
TOMM5Uncharacterized protein. (51 aa)
CISD1CDGSH iron sulfur domain 1. (165 aa)
ARMC1Armadillo repeat-containing protein 1. (282 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (281 aa)
TOMM7Translocase of outer mitochondrial membrane 7. (55 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
LOC111558941Uncharacterized protein. (291 aa)
TMEM205Transmembrane protein 205. (189 aa)
BCL2L2BCL2 like 2. (193 aa)
RHOT1Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (720 aa)
FAM210BFamily with sequence similarity 210 member B. (192 aa)
MTX2Metaxin 2. (285 aa)
MAOAAmine oxidase. (1178 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (361 aa)
BADBCL2 associated agonist of cell death. (273 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
SAMD15SAM domain-containing protein. (709 aa)
MGARPMitochondria localized glutamic acid rich protein. (241 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (428 aa)
TOMM20LTranslocase of outer mitochondrial membrane 20 like. (152 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (796 aa)
TOMM34Uncharacterized protein. (372 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (205 aa)
ENSFCAP00000056164Uncharacterized protein. (88 aa)
MFFMitochondrial fission factor. (357 aa)
SPATA18Spermatogenesis associated 18. (540 aa)
MSTO1Misato mitochondrial distribution and morphology regulator 1. (812 aa)
ENSFCAP00000059861GST_C_6 domain-containing protein. (313 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (568 aa)
ENSFCAP00000060319Uncharacterized protein. (108 aa)
LOC101083598CheR domain-containing protein. (386 aa)
BNIP3BCL2 interacting protein 3. (187 aa)
BCL2BCL2 apoptosis regulator. (237 aa)
MTX1Metaxin 1. (517 aa)
RTN4IP1Reticulon 4 interacting protein 1. (445 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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