31 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4. (409 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	INHBE	Inhibin subunit beta E. (349 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	INHA	Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
	BMP3	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
	GDF15	Growth differentiation factor 15. (307 aa)
	GDF3	Growth differentiation factor 3. (365 aa)
	GDF9	Growth differentiation factor 9. (452 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	MSTN	Myostatin. (375 aa)
	GDF11	Growth differentiation factor 11. (404 aa)
	BMP15	Bone morphogenetic protein 15. (393 aa)
	GDF6	TGF_BETA_2 domain-containing protein. (462 aa)
	BMP6	Bone morphogenetic protein 6. (502 aa)
	BMP10	TGF_BETA_2 domain-containing protein. (424 aa)
	GDF10	Growth differentiation factor 10. (503 aa)
	INHBC	Inhibin subunit beta C. (353 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	GDF5	Growth differentiation factor 5. (499 aa)
	INHBB	Inhibin subunit beta B. (407 aa)
	BMP8A	TGF_BETA_2 domain-containing protein. (402 aa)
	INHBA	Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins (By similarity). (424 aa)
	LOC101092676	TGF_BETA_2 domain-containing protein. (410 aa)
	BMP8B	TGF_BETA_2 domain-containing protein. (402 aa)
	GDF7	Growth differentiation factor 7. (455 aa)
	LOC111559734	Bone morphogenetic protein 7. (426 aa)
	LOC105261327	Left-right determination factor. (367 aa)
	ENSFCAP00000061110	TGF_BETA_2 domain-containing protein. (362 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP4	ENSFCAP00000025871	ENSFCAP00000051185	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 4.	0.448
BMP10	BMP5	ENSFCAP00000025871	ENSFCAP00000004147	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 5.	0.483
BMP10	GDF15	ENSFCAP00000025871	ENSFCAP00000009024	TGF_BETA_2 domain-containing protein.	Growth differentiation factor 15.	0.416
BMP15	GDF9	ENSFCAP00000021819	ENSFCAP00000011523	Bone morphogenetic protein 15.	Growth differentiation factor 9.	0.844
BMP15	INHA	ENSFCAP00000021819	ENSFCAP00000006196	Bone morphogenetic protein 15.	Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family.	0.539
BMP2	BMP4	ENSFCAP00000031036	ENSFCAP00000051185	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.932
BMP2	BMP5	ENSFCAP00000031036	ENSFCAP00000004147	Bone morphogenetic protein 2.	Bone morphogenetic protein 5.	0.514
BMP2	BMP6	ENSFCAP00000031036	ENSFCAP00000024856	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.953
BMP2	ENSFCAP00000061110	ENSFCAP00000031036	ENSFCAP00000061110	Bone morphogenetic protein 2.	TGF_BETA_2 domain-containing protein.	0.553
BMP2	GDF5	ENSFCAP00000031036	ENSFCAP00000035241	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.527
BMP2	LOC111559734	ENSFCAP00000031036	ENSFCAP00000051631	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.704
BMP2	TGFB1	ENSFCAP00000031036	ENSFCAP00000005040	Bone morphogenetic protein 2.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.455
BMP3	TGFB1	ENSFCAP00000007235	ENSFCAP00000005040	Bone morphogenetic protein 3; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.444
BMP4	BMP10	ENSFCAP00000051185	ENSFCAP00000025871	Bone morphogenetic protein 4.	TGF_BETA_2 domain-containing protein.	0.448
BMP4	BMP2	ENSFCAP00000051185	ENSFCAP00000031036	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.932
BMP4	BMP5	ENSFCAP00000051185	ENSFCAP00000004147	Bone morphogenetic protein 4.	Bone morphogenetic protein 5.	0.674
BMP4	BMP6	ENSFCAP00000051185	ENSFCAP00000024856	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.966
BMP4	ENSFCAP00000061110	ENSFCAP00000051185	ENSFCAP00000061110	Bone morphogenetic protein 4.	TGF_BETA_2 domain-containing protein.	0.644
BMP4	GDF5	ENSFCAP00000051185	ENSFCAP00000035241	Bone morphogenetic protein 4.	Growth differentiation factor 5.	0.446
BMP4	LOC101092676	ENSFCAP00000051185	ENSFCAP00000045841	Bone morphogenetic protein 4.	TGF_BETA_2 domain-containing protein.	0.448