(16 nodes) SMAD-like domain superfamily network (Felis catus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	IRF5	Interferon regulatory factor 5. (504 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	IRF3	Interferon regulatory factor 3. (420 aa)
	SMAD6	Mothers against decapentaplegic homolog. (497 aa)
	IRF6	Interferon regulatory factor 6. (480 aa)
	IRF9	Interferon regulatory factor 9. (411 aa)
	IRF4	Interferon regulatory factor 4. (451 aa)
	SMAD3	Mothers against decapentaplegic homolog. (457 aa)
	SMAD9	Mothers against decapentaplegic homolog. (430 aa)
	SMAD7	Mothers against decapentaplegic homolog. (426 aa)
	IRF7	Interferon regulatory factor 7. (512 aa)
	IRF8	Interferon regulatory factor 8. (427 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	SMAD2	Mothers against decapentaplegic homolog. (721 aa)
	LOC101080774	IRF tryptophan pentad repeat domain-containing protein. (467 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IRF3	IRF7	ENSFCAP00000005645	ENSFCAP00000046253	Interferon regulatory factor 3.	Interferon regulatory factor 7.	0.997
IRF3	IRF9	ENSFCAP00000005645	ENSFCAP00000015403	Interferon regulatory factor 3.	Interferon regulatory factor 9.	0.484
IRF3	SMAD3	ENSFCAP00000005645	ENSFCAP00000034334	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.463
IRF4	LOC101080774	ENSFCAP00000024564	ENSFCAP00000061575	Interferon regulatory factor 4.	IRF tryptophan pentad repeat domain-containing protein.	0.900
IRF7	IRF3	ENSFCAP00000046253	ENSFCAP00000005645	Interferon regulatory factor 7.	Interferon regulatory factor 3.	0.997
IRF9	IRF3	ENSFCAP00000015403	ENSFCAP00000005645	Interferon regulatory factor 9.	Interferon regulatory factor 3.	0.484
LOC101080774	IRF4	ENSFCAP00000061575	ENSFCAP00000024564	IRF tryptophan pentad repeat domain-containing protein.	Interferon regulatory factor 4.	0.900
SMAD1	SMAD2	ENSFCAP00000003810	ENSFCAP00000057862	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.953
SMAD1	SMAD3	ENSFCAP00000003810	ENSFCAP00000034334	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.771
SMAD1	SMAD4	ENSFCAP00000003810	ENSFCAP00000031311	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.999
SMAD1	SMAD5	ENSFCAP00000003810	ENSFCAP00000050960	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.967
SMAD1	SMAD6	ENSFCAP00000003810	ENSFCAP00000011413	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.979
SMAD1	SMAD7	ENSFCAP00000003810	ENSFCAP00000042878	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.947
SMAD1	SMAD9	ENSFCAP00000003810	ENSFCAP00000042712	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.858
SMAD2	SMAD1	ENSFCAP00000057862	ENSFCAP00000003810	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.953
SMAD2	SMAD3	ENSFCAP00000057862	ENSFCAP00000034334	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.996
SMAD2	SMAD4	ENSFCAP00000057862	ENSFCAP00000031311	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.999
SMAD2	SMAD5	ENSFCAP00000057862	ENSFCAP00000050960	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.839
SMAD2	SMAD6	ENSFCAP00000057862	ENSFCAP00000011413	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.957
SMAD2	SMAD7	ENSFCAP00000057862	ENSFCAP00000042878	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.969