5 items (Felis catus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BCL2L1	BCL2 like 1. (271 aa)
	BCL2	BCL2 apoptosis regulator. (237 aa)
	BAX	BCL2 associated X, apoptosis regulator. (192 aa)
	MCL1	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity). (350 aa)
	HRK	Activator of apoptosis harakiri; Promotes apoptosis. (91 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	BCL2	ENSFCAP00000000237	ENSFCAP00000062072	BCL2 associated X, apoptosis regulator.	BCL2 apoptosis regulator.	0.966
BAX	BCL2L1	ENSFCAP00000000237	ENSFCAP00000059067	BCL2 associated X, apoptosis regulator.	BCL2 like 1.	0.949
BAX	MCL1	ENSFCAP00000000237	ENSFCAP00000023698	BCL2 associated X, apoptosis regulator.	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).	0.469
BCL2	BAX	ENSFCAP00000062072	ENSFCAP00000000237	BCL2 apoptosis regulator.	BCL2 associated X, apoptosis regulator.	0.966
BCL2	BCL2L1	ENSFCAP00000062072	ENSFCAP00000059067	BCL2 apoptosis regulator.	BCL2 like 1.	0.983
BCL2	HRK	ENSFCAP00000062072	ENSFCAP00000050054	BCL2 apoptosis regulator.	Activator of apoptosis harakiri; Promotes apoptosis.	0.851
BCL2	MCL1	ENSFCAP00000062072	ENSFCAP00000023698	BCL2 apoptosis regulator.	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).	0.505
BCL2L1	BAX	ENSFCAP00000059067	ENSFCAP00000000237	BCL2 like 1.	BCL2 associated X, apoptosis regulator.	0.949
BCL2L1	BCL2	ENSFCAP00000059067	ENSFCAP00000062072	BCL2 like 1.	BCL2 apoptosis regulator.	0.983
BCL2L1	HRK	ENSFCAP00000059067	ENSFCAP00000050054	BCL2 like 1.	Activator of apoptosis harakiri; Promotes apoptosis.	0.746
BCL2L1	MCL1	ENSFCAP00000059067	ENSFCAP00000023698	BCL2 like 1.	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).	0.851
HRK	BCL2	ENSFCAP00000050054	ENSFCAP00000062072	Activator of apoptosis harakiri; Promotes apoptosis.	BCL2 apoptosis regulator.	0.851
HRK	BCL2L1	ENSFCAP00000050054	ENSFCAP00000059067	Activator of apoptosis harakiri; Promotes apoptosis.	BCL2 like 1.	0.746
HRK	MCL1	ENSFCAP00000050054	ENSFCAP00000023698	Activator of apoptosis harakiri; Promotes apoptosis.	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).	0.845
MCL1	BAX	ENSFCAP00000023698	ENSFCAP00000000237	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).	BCL2 associated X, apoptosis regulator.	0.469
MCL1	BCL2	ENSFCAP00000023698	ENSFCAP00000062072	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).	BCL2 apoptosis regulator.	0.505
MCL1	BCL2L1	ENSFCAP00000023698	ENSFCAP00000059067	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).	BCL2 like 1.	0.851
MCL1	HRK	ENSFCAP00000023698	ENSFCAP00000050054	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).	Activator of apoptosis harakiri; Promotes apoptosis.	0.845