STRINGSTRING
SOCS5 SOCS5 TNS2 TNS2 SH2D4B SH2D4B SH2D5 SH2D5 SHC1 SHC1 JAK1 JAK1 NCK2 NCK2 STAT5B STAT5B STAT3 STAT3 SH2B3 SH2B3 SH2D6 SH2D6 SUPT6H SUPT6H FRK FRK TNS3 TNS3 GRB14 GRB14 CHN1 CHN1 STAT5A STAT5A PLCG1 PLCG1 RINL RINL GRAP GRAP SH2D3C SH2D3C RIN2 RIN2 FES FES SH2D1B SH2D1B STAT1 STAT1 CISH CISH CSK CSK CLNK CLNK JAK2 JAK2 YES1 YES1 SOCS1 SOCS1 SHB SHB PIK3R3 PIK3R3 VAV3 VAV3 CRK CRK SHD SHD PIK3R2 PIK3R2 SHC3 SHC3 PTPN6 PTPN6 VAV1 VAV1 ABL1 ABL1 ABL2 ABL2 INPPL1 INPPL1 CRKL CRKL SH2D2A SH2D2A JAK3 JAK3 SHF SHF FGR FGR SH2D1A SH2D1A CHN2 CHN2 SRMS SRMS HSH2D HSH2D SOCS6 SOCS6 RIN1 RIN1 TYK2 TYK2 TNS4 TNS4 GRB7 GRB7 ITK ITK ZAP70 ZAP70 BMX BMX SH2D7 SH2D7 PIK3R1 PIK3R1 INPP5D INPP5D VAV2 VAV2 STAT2 STAT2 GRB10 GRB10 SLA2 SLA2 FER FER GRAP2 GRAP2 SH3BP2 SH3BP2 STAP2 STAP2 SH2B2 SH2B2 CBLC CBLC LCP2 LCP2 CBLB CBLB STAP1 STAP1 HCK HCK PTK6 PTK6 SHC4 SHC4 PTPN11 PTPN11 SOCS4 SOCS4 BCAR3 BCAR3 SOCS7 SOCS7 TEC TEC TNS1 TNS1 LCK LCK SHE SHE CRADD CRADD NCK1 NCK1 BLNK BLNK SLA SLA RASA1 RASA1 SRC SRC SH2B1 SH2B1 SYK SYK TXK TXK STAT6 STAT6 BLK BLK SHC2 SHC2 PLCG2 PLCG2 STAT4 STAT4 SH2D4A SH2D4A CBL CBL RIN3 RIN3 MATK MATK SH2D3A SH2D3A SOCS3 SOCS3 FYN FYN LOC101082222 LOC101082222 BTK BTK LYN LYN GRB2 GRB2 DAPP1 DAPP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS5Suppressor of cytokine signaling 5. (536 aa)
TNS2Tensin 2. (1409 aa)
SH2D4BSH2 domain containing 4B. (400 aa)
SH2D5SH2 domain containing 5. (428 aa)
SHC1SHC adaptor protein 1. (566 aa)
JAK1Tyrosine-protein kinase. (1157 aa)
NCK2Cytoplasmic protein. (380 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
SH2B3SH2B adaptor protein 3. (578 aa)
SH2D6SH2 domain containing 6. (365 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
FRKTyrosine-protein kinase. (514 aa)
TNS3Tensin 3. (1553 aa)
GRB14Growth factor receptor bound protein 14. (717 aa)
CHN1Uncharacterized protein. (539 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
PLCG1Phosphoinositide phospholipase C. (1391 aa)
RINLRas and Rab interactor like. (611 aa)
GRAPUncharacterized protein. (332 aa)
SH2D3CSH2 domain containing 3C. (860 aa)
RIN2Ras and Rab interactor 2. (933 aa)
FESTyrosine-protein kinase Fes/Fps; Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF [...] (861 aa)
SH2D1BSH2 domain-containing protein. (135 aa)
STAT1Signal transducer and activator of transcription. (885 aa)
CISHCytokine inducible SH2 containing protein. (257 aa)
CSKTyrosine-protein kinase. (549 aa)
CLNKCytokine dependent hematopoietic cell linker. (426 aa)
JAK2Tyrosine-protein kinase. (1131 aa)
YES1Tyrosine-protein kinase. (546 aa)
SOCS1Suppressor of cytokine signaling 1. (203 aa)
SHBSH2 domain-containing protein. (508 aa)
PIK3R3Uncharacterized protein. (461 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
SHDSrc homology 2 domain containing transforming protein D. (340 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
SHC3SHC adaptor protein 3. (587 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (615 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
ABL2Tyrosine-protein kinase. (1160 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
CRKLCRK like proto-oncogene, adaptor protein. (342 aa)
SH2D2ASH2 domain containing 2A. (383 aa)
JAK3Tyrosine-protein kinase. (1232 aa)
SHFSrc homology 2 domain containing F. (489 aa)
FGRTyrosine-protein kinase. (527 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
CHN2Chimaerin; GTPase-activating protein for p21-rac. (496 aa)
SRMSTyrosine-protein kinase. (507 aa)
HSH2DHematopoietic SH2 domain containing. (383 aa)
SOCS6Suppressor of cytokine signaling 6. (497 aa)
RIN1Ras and Rab interactor 1. (790 aa)
TYK2Tyrosine-protein kinase. (1181 aa)
TNS4Tensin 4. (715 aa)
GRB7Growth factor receptor bound protein 7. (530 aa)
ITKTyrosine-protein kinase. (620 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
BMXTyrosine-protein kinase. (630 aa)
SH2D7SH2 domain containing 7. (452 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1181 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
STAT2Signal transducer and activator of transcription. (855 aa)
GRB10Growth factor receptor bound protein 10. (594 aa)
SLA2Src like adaptor 2. (262 aa)
FERTyrosine-protein kinase. (456 aa)
GRAP2GRB2 related adaptor protein 2. (322 aa)
SH3BP2SH3 domain binding protein 2. (590 aa)
STAP2Signal transducing adaptor family member 2. (393 aa)
SH2B2SH2B adaptor protein 2. (679 aa)
CBLCCbl proto-oncogene C. (494 aa)
LCP2Lymphocyte cytosolic protein 2. (534 aa)
CBLBCbl proto-oncogene B. (1182 aa)
STAP1Signal transducing adaptor family member 1. (282 aa)
HCKTyrosine-protein kinase. (523 aa)
PTK6Tyrosine-protein kinase. (450 aa)
SHC4SHC adaptor protein 4. (630 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
SOCS4Suppressor of cytokine signaling 4. (441 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (935 aa)
SOCS7Suppressor of cytokine signaling 7. (640 aa)
TECTyrosine-protein kinase. (650 aa)
TNS1Tensin 1. (1901 aa)
LCKTyrosine-protein kinase. (520 aa)
SHESrc homology 2 domain containing E. (460 aa)
CRADDUncharacterized protein. (398 aa)
NCK1Cytoplasmic protein. (455 aa)
BLNKB cell linker. (479 aa)
SLAUncharacterized protein. (291 aa)
RASA1RAS p21 protein activator 1. (1039 aa)
SRCTyrosine-protein kinase. (678 aa)
SH2B1SH2B adaptor protein 1. (757 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
TXKTyrosine-protein kinase. (551 aa)
STAT6Signal transducer and activator of transcription. (844 aa)
BLKTyrosine-protein kinase. (500 aa)
SHC2SHC adaptor protein 2. (583 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1318 aa)
STAT4Signal transducer and activator of transcription. (758 aa)
SH2D4ASH2 domain containing 4A. (453 aa)
CBLCbl proto-oncogene. (902 aa)
RIN3Ras and Rab interactor 3. (982 aa)
MATKTyrosine-protein kinase. (838 aa)
SH2D3ASH2 domain containing 3A. (576 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
FYNTyrosine-protein kinase. (589 aa)
LOC101082222Uncharacterized protein. (570 aa)
BTKTyrosine-protein kinase. (692 aa)
LYNTyrosine-protein kinase. (526 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (351 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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