STRINGSTRING
PFDN4 PFDN4 PSMG2 PSMG2 CCT6B CCT6B HSPE1 HSPE1 TIMM8A TIMM8A GRPEL1 GRPEL1 TIMM13 TIMM13 CLGN CLGN ENSFCAP00000055551 ENSFCAP00000055551 PSMG1 PSMG1 CCT5 CCT5 TCP1 TCP1 CCT2 CCT2 CALR CALR CRYAA CRYAA TIMM8B TIMM8B M3X4I6_FELCA M3X4I6_FELCA CCT8 CCT8 CALR3 CALR3 TBCA TBCA CCT8L2 CCT8L2 ENSFCAP00000037673 ENSFCAP00000037673 CCT3 CCT3 GRPEL2 GRPEL2 CANX CANX M3X271_FELCA M3X271_FELCA CCT6A CCT6A VBP1 VBP1 MDN1 MDN1 M3WUF4_FELCA M3WUF4_FELCA CRYAB CRYAB CCT4 CCT4 CCT7 CCT7 SDHAF2 SDHAF2 RSAD1 RSAD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (152 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (266 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (541 aa)
HSPE1Heat shock protein family E (Hsp10) member 1; Belongs to the GroES chaperonin family. (102 aa)
TIMM8Azf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (97 aa)
GRPEL1GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
TIMM13Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family. (95 aa)
CLGNCalmegin. (654 aa)
ENSFCAP00000055551Uncharacterized protein. (429 aa)
PSMG1Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2. (306 aa)
CCT5Chaperonin containing TCP1 subunit 5. (542 aa)
TCP1T-complex 1. (556 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
CALRCalreticulin. (417 aa)
CRYAAAlpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. (173 aa)
TIMM8BTranslocase of inner mitochondrial membrane 8 homolog B; Belongs to the small Tim family. (204 aa)
M3X4I6_FELCAUncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
CCT8Chaperonin containing TCP1 subunit 8. (553 aa)
CALR3Calreticulin. (385 aa)
TBCATubulin-specific chaperone A; Belongs to the TBCA family. (108 aa)
CCT8L2Chaperonin containing TCP1 subunit 8 like 2. (554 aa)
ENSFCAP00000037673Uncharacterized protein; Belongs to the GroES chaperonin family. (99 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
GRPEL2GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (380 aa)
CANXCalnexin. (637 aa)
M3X271_FELCAUncharacterized protein; Belongs to the GroES chaperonin family. (87 aa)
CCT6AChaperonin containing TCP1 subunit 6A. (526 aa)
VBP1Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5578 aa)
M3WUF4_FELCAUncharacterized protein; Belongs to the GroES chaperonin family. (105 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
CCT4T-complex protein 1 subunit delta. (628 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)
RSAD1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (450 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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