53 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LDHD	Lactate dehydrogenase D. (566 aa)
	TIMM17B	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (172 aa)
	CHCHD10	Coiled-coil-helix-coiled-coil-helix domain containing 10. (237 aa)
	BCS1L	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
	CMC2	COX assembly mitochondrial protein. (151 aa)
	COX17	Cytochrome c oxidase copper chaperone COX17. (63 aa)
	GFER	Sulfhydryl oxidase. (408 aa)
	OTC	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
	ATP5F1B	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
	COQ2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (362 aa)
	TIMM44	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (454 aa)
	COA4	Cytochrome c oxidase assembly factor 4 homolog. (91 aa)
	CMC4	C-X9-C motif containing 4. (68 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
	CHCHD5	Coiled-coil-helix-coiled-coil-helix domain containing 5. (110 aa)
	TAZ	Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (262 aa)
	M3X1T3_FELCA	CHCH domain-containing protein. (146 aa)
	TIMM21	Translocase of inner mitochondrial membrane 21. (244 aa)
	TIMM8B	Translocase of inner mitochondrial membrane 8 homolog B; Belongs to the small Tim family. (204 aa)
	FXN	Frataxin. (211 aa)
	DNAJC15	DnaJ heat shock protein family (Hsp40) member C15. (149 aa)
	ENSFCAP00000025816	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (145 aa)
	TIMM10	Translocase of inner mitochondrial membrane 10. (90 aa)
	SPIRE2	Spire type actin nucleation factor 2. (766 aa)
	TIMM9	Translocase of inner mitochondrial membrane 9. (89 aa)
	LOC101082948	Uncharacterized protein. (79 aa)
	CHCHD2	Coiled-coil-helix-coiled-coil-helix domain containing 2. (153 aa)
	ENSFCAP00000039396	Uncharacterized protein. (59 aa)
	LOC101094135	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (209 aa)
	ENSFCAP00000039745	Uncharacterized protein. (55 aa)
	GRPEL2	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (380 aa)
	ENSFCAP00000040280	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (127 aa)
	NDUFB8	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
	TIMM22	Translocase of inner mitochondrial membrane 22. (194 aa)
	TIMM8A	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (97 aa)
	MTX2	Metaxin 2. (285 aa)
	HSCB	HscB mitochondrial iron-sulfur cluster cochaperone. (235 aa)
	LOC111559191	Mitochondrial import inner membrane translocase subunit Tim8 A. (97 aa)
	ENSFCAP00000048291	Uncharacterized protein. (113 aa)
	GRPEL1	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
	CHCHD7	Coiled-coil-helix-coiled-coil-helix domain containing 7. (109 aa)
	TIMM13	Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family. (95 aa)
	CHCHD4	CHCH domain-containing protein. (141 aa)
	DNAJC19	Uncharacterized protein. (144 aa)
	ENSFCAP00000053559	Uncharacterized protein; Belongs to the ATPase C chain family. (135 aa)
	TIMM10B	zf-Tim10_DDP domain-containing protein. (103 aa)
	TIMM17A	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (208 aa)
	CHCHD3	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (276 aa)
	PITRM1	Pitrilysin metallopeptidase 1. (1043 aa)
	ATP5MC1	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (142 aa)
	LOC111559039	M16C_associated domain-containing protein. (568 aa)
	TIMM50	Translocase of inner mitochondrial membrane 50. (608 aa)
	C3orf18	Chromosome 3 open reading frame 18. (182 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP5F1B	ATP5MC1	ENSFCAP00000011162	ENSFCAP00000058934	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family.	0.997
ATP5F1B	BCS1L	ENSFCAP00000011162	ENSFCAP00000003827	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	0.455
ATP5F1B	CHCHD3	ENSFCAP00000011162	ENSFCAP00000057488	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.483
ATP5F1B	COQ2	ENSFCAP00000011162	ENSFCAP00000013561	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.643
ATP5F1B	ENSFCAP00000025816	ENSFCAP00000011162	ENSFCAP00000025816	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.494
ATP5F1B	ENSFCAP00000039745	ENSFCAP00000011162	ENSFCAP00000039745	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.494
ATP5F1B	ENSFCAP00000040280	ENSFCAP00000011162	ENSFCAP00000040280	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.494
ATP5F1B	ENSFCAP00000053559	ENSFCAP00000011162	ENSFCAP00000053559	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein; Belongs to the ATPase C chain family.	0.996
ATP5F1B	FXN	ENSFCAP00000011162	ENSFCAP00000022691	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Frataxin.	0.721
ATP5F1B	HSPD1	ENSFCAP00000011162	ENSFCAP00000019234	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family.	0.494
ATP5F1B	LDHD	ENSFCAP00000011162	ENSFCAP00000051814	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Lactate dehydrogenase D.	0.523
ATP5F1B	LOC101094135	ENSFCAP00000011162	ENSFCAP00000039404	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.403
ATP5F1B	LOC111559039	ENSFCAP00000011162	ENSFCAP00000059154	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	M16C_associated domain-containing protein.	0.447
ATP5F1B	NDUFB8	ENSFCAP00000011162	ENSFCAP00000042929	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.784
ATP5F1B	OTC	ENSFCAP00000011162	ENSFCAP00000010105	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.486
ATP5F1B	PITRM1	ENSFCAP00000011162	ENSFCAP00000058350	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Pitrilysin metallopeptidase 1.	0.447
ATP5F1B	TIMM44	ENSFCAP00000011162	ENSFCAP00000013865	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.417
ATP5F1B	TIMM50	ENSFCAP00000011162	ENSFCAP00000061154	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Translocase of inner mitochondrial membrane 50.	0.494
ATP5MC1	ATP5F1B	ENSFCAP00000058934	ENSFCAP00000011162	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.997
ATP5MC1	NDUFB8	ENSFCAP00000058934	ENSFCAP00000042929	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.790