Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGER | APP | ENSFCAP00000004183 | ENSFCAP00000001445 | Advanced glycosylation end-product specific receptor. | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | 0.633 |
| AGER | HMGB1 | ENSFCAP00000004183 | ENSFCAP00000058007 | Advanced glycosylation end-product specific receptor. | Uncharacterized protein. | 0.727 |
| AGER | NFKB1 | ENSFCAP00000004183 | ENSFCAP00000006998 | Advanced glycosylation end-product specific receptor. | Nuclear factor kappa B subunit 1. | 0.461 |
| AGER | NFKB2 | ENSFCAP00000004183 | ENSFCAP00000001153 | Advanced glycosylation end-product specific receptor. | Nuclear factor kappa B subunit 2. | 0.420 |
| AGER | RELA | ENSFCAP00000004183 | ENSFCAP00000048226 | Advanced glycosylation end-product specific receptor. | RELA proto-oncogene, NF-kB subunit. | 0.407 |
| AGER | S100A12 | ENSFCAP00000004183 | ENSFCAP00000013038 | Advanced glycosylation end-product specific receptor. | EF-hand domain-containing protein; Belongs to the S-100 family. | 0.768 |
| AGER | S100B | ENSFCAP00000004183 | ENSFCAP00000036720 | Advanced glycosylation end-product specific receptor. | Protein S100; Belongs to the S-100 family. | 0.954 |
| ALPK1 | IRAK1 | ENSFCAP00000009946 | ENSFCAP00000010077 | Alpha kinase 1. | Interleukin 1 receptor associated kinase 1. | 0.451 |
| ALPK1 | IRAK2 | ENSFCAP00000009946 | ENSFCAP00000010439 | Alpha kinase 1. | Interleukin 1 receptor associated kinase 2. | 0.465 |
| ALPK1 | MAP3K20 | ENSFCAP00000009946 | ENSFCAP00000046539 | Alpha kinase 1. | Uncharacterized protein. | 0.409 |
| ALPK1 | MAP3K7 | ENSFCAP00000009946 | ENSFCAP00000017301 | Alpha kinase 1. | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.523 |
| ALPK1 | TIFA | ENSFCAP00000009946 | ENSFCAP00000051040 | Alpha kinase 1. | FHA domain-containing protein. | 0.944 |
| ALPK1 | TRAF6 | ENSFCAP00000009946 | ENSFCAP00000047805 | Alpha kinase 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.636 |
| APP | AGER | ENSFCAP00000001445 | ENSFCAP00000004183 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | Advanced glycosylation end-product specific receptor. | 0.633 |
| APP | CREB1 | ENSFCAP00000001445 | ENSFCAP00000007617 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | cAMP responsive element binding protein 1. | 0.455 |
| APP | NFKB1 | ENSFCAP00000001445 | ENSFCAP00000006998 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | Nuclear factor kappa B subunit 1. | 0.530 |
| APP | NFKB2 | ENSFCAP00000001445 | ENSFCAP00000001153 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | Nuclear factor kappa B subunit 2. | 0.469 |
| APP | S100A12 | ENSFCAP00000001445 | ENSFCAP00000013038 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | EF-hand domain-containing protein; Belongs to the S-100 family. | 0.408 |
| APP | S100B | ENSFCAP00000001445 | ENSFCAP00000036720 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | Protein S100; Belongs to the S-100 family. | 0.535 |
| APP | TLR4 | ENSFCAP00000001445 | ENSFCAP00000023731 | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] | 0.517 |
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