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| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | CDC73 | Cell division cycle 73. (531 aa) |
| | BCL9 | BCL9 transcription coactivator. (1340 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (478 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (355 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | BCL9L | BCL9 like. (1393 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | CCDC88C | Coiled-coil domain containing 88C. (2023 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) |
| | XPO1 | Exportin 1. (1071 aa) |
| | FRAT1 | Uncharacterized protein. (281 aa) |
| | SOX10 | SRY-box transcription factor 10. (604 aa) |
| | SOX13 | SRY-box 13. (619 aa) |
| | RYK | Receptor like tyrosine kinase. (609 aa) |
| | CTNNB1 | Catenin beta 1. (783 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | M3W104_FELCA | Histone domain-containing protein; Belongs to the histone H2B family. (88 aa) |
| | SOX30 | SRY-box 30. (768 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (606 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (951 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | EP300 | E1A binding protein p300. (2425 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | RSPO2 | R-spondin 2. (242 aa) |
| | CREBBP | CREB binding protein. (2444 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (700 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (718 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | LGR5 | Leucine rich repeat containing G protein-coupled receptor 5. (907 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | RSPO3 | R-spondin 3. (279 aa) |
| | SOX15 | SRY-box 15. (233 aa) |
| | UBA52 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa) |
| | WIF1 | WNT inhibitory factor 1. (587 aa) |
| | PSMA1 | Proteasome subunit alpha type. (263 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (454 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2583 aa) |
| | TLE6 | TLE family member 6, subcortical maternal complex member. (583 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | H2BC1 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | RNF146 | Ring finger protein 146. (356 aa) |
| | RSPO4 | R-spondin 4. (232 aa) |
| | KREMEN2 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa) |
| | PSMD9 | Proteasome 26S subunit, non-ATPase 9. (284 aa) |
| | PSMB11 | Proteasome subunit beta. (276 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | PSMA6 | Proteasome subunit alpha type. (251 aa) |
| | CBY1 | Chibby family member 1, beta catenin antagonist. (127 aa) |
| | YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa) |
| | RPS27A | Ribosomal protein S27a. (156 aa) |
| | LEO1 | LEO1 homolog, Paf1/RNA polymerase II complex component. (664 aa) |
| | M3WZ36_FELCA | Histone H2A; Belongs to the histone H2A family. (140 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (748 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) |
| | LOC101096314 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H3F3A | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | H2BU1 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) |
| | LOC101083848 | Proteasome subunit beta. (209 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | LOC101088423 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (652 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | LOC101092488 | Histone domain-containing protein; Belongs to the histone H2B family. (127 aa) |
| | GSK3A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa) |
| | LY6G5B | Lymphocyte antigen 6 family member G5B. (216 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | ZNRF3 | Zinc and ring finger 3. (1087 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | LOC101097798 | Histone H2A; Belongs to the histone H2A family. (113 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | AXIN2 | Axin 2. (841 aa) |
| | M3XDD6_FELCA | Histone domain-containing protein; Belongs to the histone H2B family. (121 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1620 aa) |
| | ZBTB44 | Zinc finger and BTB domain containing 44. (616 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | LOC101083171 | Proteasome subunit beta. (276 aa) |
| | TLE7 | TLE family member 7. (437 aa) |
| | RNF43 | RING-type domain-containing protein. (782 aa) |
| | LOC101087401 | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | ENSFCAP00000026617 | Ubiquitin-like domain-containing protein. (78 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | ENSFCAP00000026978 | Uncharacterized protein. (111 aa) |
| | LRTM1 | Leucine rich repeats and transmembrane domains 1. (345 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | HMGXB4 | HMG-box containing 4. (601 aa) |
| | ENSFCAP00000028809 | Histone H2B; Belongs to the histone H2B family. (67 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1327 aa) |
| | SOX14 | SRY-box transcription factor 14. (240 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | SOX7 | Uncharacterized protein. (571 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (221 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (315 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | ASH2L | ASH2 like, histone lysine methyltransferase complex subunit. (634 aa) |
| | TLE5 | TLE family member 5, transcriptional modulator. (316 aa) |
| | LOC109502223 | Ubiquitin-like domain-containing protein. (176 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | SOX6 | SRY-box 6. (884 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (341 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | ENSFCAP00000036869 | Proteasome subunit alpha type. (197 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (586 aa) |
| | KXD1 | KxDL motif containing 1. (201 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (406 aa) |
| | SOX8 | SRY-box 8. (883 aa) |
| | APC | APC regulator of WNT signaling pathway. (2874 aa) |
| | H2AZ2 | Histone H2A; Belongs to the histone H2A family. (166 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (385 aa) |
| | SOX12 | Transcription factor SOX. (314 aa) |
| | LOC111556170 | Proteasome subunit beta type-8. (276 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (558 aa) |
| | LOC101082235 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | SOX17 | SRY-box transcription factor 17. (406 aa) |
| | HMGXB3 | HMG-box containing 3. (1540 aa) |
| | HIST2H3C | Histone cluster 2 H3 family member c. (258 aa) |
| | LOC105260541 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | SOX18 | SRY-box transcription factor 18. (465 aa) |
| | LOC111556171 | Uncharacterized protein. (234 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2289 aa) |
| | ENSFCAP00000041674 | AAA domain-containing protein; Belongs to the AAA ATPase family. (189 aa) |
| | ENSFCAP00000041747 | Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (88 aa) |
| | LOC101095347 | Histone H4. (103 aa) |
| | ENSFCAP00000042498 | Histone domain-containing protein; Belongs to the histone H2B family. (118 aa) |
| | FRAT2 | FRAT regulator of WNT signaling pathway 2. (234 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (805 aa) |
| | PIP5K1B | Phosphatidylinositol-4-phosphate 5-kinase type 1 beta. (548 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa) |
| | ENSFCAP00000043372 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | TLE2 | TLE family member 2, transcriptional corepressor. (772 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (857 aa) |
| | GSK3B | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | H3C13 | H3 clustered histone 13. (136 aa) |
| | LOC101084193 | Histone H4. (103 aa) |
| | LOC101095347-2 | Histone H4. (103 aa) |
| | LOC101093269 | Histone H3.1. (136 aa) |
| | SOST | Sclerostin. (212 aa) |
| | LOC101082491 | Histone H4. (103 aa) |
| | LOC101082235-2 | Histone H2B type 1. (126 aa) |
| | SOX9 | SRY-box transcription factor 9. (511 aa) |
| | LOC101088237 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | LOC101095347-3 | Histone H4. (103 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (735 aa) |
| | TNKS2 | Poly [ADP-ribose] polymerase. (1344 aa) |
| | LOC101083933 | Histone H4. (103 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | DACT3 | Dishevelled binding antagonist of beta catenin 3. (631 aa) |
| | SOX5 | SRY-box transcription factor 5. (787 aa) |
| | PSMA4 | Proteasome subunit alpha type. (277 aa) |
| | LOC101082235-3 | Histone H2B type 1. (126 aa) |
| | PSME4 | Proteasome activator subunit 4. (1865 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (484 aa) |
| | CXXC4 | CXXC finger protein 4. (373 aa) |
| | SOX21 | SRY-box transcription factor 21. (276 aa) |
| | DKK2 | Dickkopf WNT signaling pathway inhibitor 2. (259 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (840 aa) |
| | LOC105260541-2 | Histone H3.1. (136 aa) |
| | LOC101082405 | AAA domain-containing protein. (330 aa) |
| | LOC101084708 | Histone H4. (103 aa) |
| | LGR6 | LRRNT domain-containing protein. (967 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (415 aa) |
| | LOC101080886 | Histone H3.1. (136 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (423 aa) |
| | LOC101088485 | Histone H2B type 1. (125 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | ENSFCAP00000048881 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | LOC101095347-4 | Histone H4. (103 aa) |
| | LOC105260541-3 | Histone H3.1. (136 aa) |
| | LOC101080632 | Histone H3.1. (136 aa) |
| | LOC101084959 | Histone H3.1. (136 aa) |
| | LOC101082235-4 | Histone H2B type 1. (126 aa) |
| | LOC101082235-5 | Histone H2B type 1. (126 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (673 aa) |
| | MEN1 | Menin 1. (749 aa) |
| | LOC101086971 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC101087478 | Histone H4. (103 aa) |
| | PSME2 | Proteasome activator subunit 2. (253 aa) |
| | SOX4 | Transcription factor SOX. (459 aa) |
| | LOC101082235-6 | Histone H2B type 1. (126 aa) |
| | PSME3 | Uncharacterized protein. (265 aa) |
| | TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3872 aa) |
| | USP34 | Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3519 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (336 aa) |
| | LOC101089514 | Histone H3.1. (136 aa) |
| | PSMB1 | Proteasome subunit beta. (261 aa) |
| | SLC39A13 | Solute carrier family 39 member 13. (612 aa) |
| | ENSFCAP00000053469 | PA28_beta domain-containing protein. (192 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (778 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1132 aa) |
| | H2BC5 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa) |
| | PSMA3 | Proteasome subunit alpha type. (258 aa) |
| | BHMG1 | Basic helix-loop-helix and HMG-box containing 1. (591 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa) |
| | H2AX | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | PYGO1 | Pygopus family PHD finger 1. (419 aa) |
| | ENSFCAP00000055099 | Uncharacterized protein. (115 aa) |
| | RBBP5 | RB binding protein 5, histone lysine methyltransferase complex subunit. (543 aa) |
| | LOC101089767 | Histone H4. (103 aa) |
| | SOX11 | Transcription factor SOX. (412 aa) |
| | ENSFCAP00000056245 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (178 aa) |
| | TCF7 | Transcription factor 7. (556 aa) |
| | PSMA7 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (358 aa) |
| | RSPO1 | R-spondin 1. (299 aa) |
| | LOC101082235-7 | Histone H2B type 1. (126 aa) |
| | LOC101083921 | Histone H4. (103 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa) |
| | PSMB3 | Proteasome subunit beta. (268 aa) |
| | KLHL12 | Kelch like family member 12. (838 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (571 aa) |
| | CTBP1 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (467 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1302 aa) |
| | H2BE1 | Histone H2B; Belongs to the histone H2B family. (122 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (595 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (837 aa) |
| | LOC101092762 | Histone H4. (103 aa) |
