25 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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gene fusions

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protein homology

Your Input:
	LOC101097703	EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
	ENSFCAP00000029012	Uncharacterized protein; Belongs to the calmodulin family. (124 aa)
	CAV1	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
	SPR	Sepiapterin reductase. (267 aa)
	FMN1	Formin 1. (1417 aa)
	CALM1	Uncharacterized protein; Belongs to the calmodulin family. (192 aa)
	FMN2	Formin 2. (1793 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (276 aa)
	DDAH1	Dimethylarginine dimethylaminohydrolase 1. (330 aa)
	CYGB	Cytoglobin; Belongs to the globin family. (313 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)
	ENSFCAP00000060347	Uncharacterized protein; Belongs to the calmodulin family. (146 aa)
	NOSTRIN	Nitric oxide synthase trafficking. (546 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	ZDHHC21	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (299 aa)
	WASL	WASP like actin nucleation promoting factor. (505 aa)
	DDAH2	Dimethylarginine dimethylaminohydrolase 2. (285 aa)
	LYPLA1	Lysophospholipase 1. (230 aa)
	M3WQU5_FELCA	EF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	RECQL	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (652 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
	NOSIP	Nitric oxide synthase-interacting protein; Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family. (301 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (867 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	NOS3	ENSFCAP00000004586	ENSFCAP00000012234	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase; Produces nitric oxide (NO).	0.950
AKT1	SPR	ENSFCAP00000004586	ENSFCAP00000034949	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Sepiapterin reductase.	0.458
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	NOS3	ENSFCAP00000059662	ENSFCAP00000012234	Non-specific serine/threonine protein kinase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.950
AKT2	SPR	ENSFCAP00000059662	ENSFCAP00000034949	Non-specific serine/threonine protein kinase.	Sepiapterin reductase.	0.458
CALM1	CAV1	ENSFCAP00000050555	ENSFCAP00000029296	Uncharacterized protein; Belongs to the calmodulin family.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.484
CALM1	NOS3	ENSFCAP00000050555	ENSFCAP00000012234	Uncharacterized protein; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.508
CALM2	CALM3	ENSFCAP00000016531	ENSFCAP00000055336	Calmodulin 2; Belongs to the calmodulin family.	Calmodulin 3; Belongs to the calmodulin family.	0.801
CALM2	CAV1	ENSFCAP00000016531	ENSFCAP00000029296	Calmodulin 2; Belongs to the calmodulin family.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.914
CALM2	NOS3	ENSFCAP00000016531	ENSFCAP00000012234	Calmodulin 2; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.948
CALM3	CALM2	ENSFCAP00000055336	ENSFCAP00000016531	Calmodulin 3; Belongs to the calmodulin family.	Calmodulin 2; Belongs to the calmodulin family.	0.801
CALM3	CAV1	ENSFCAP00000055336	ENSFCAP00000029296	Calmodulin 3; Belongs to the calmodulin family.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.484
CALM3	NOS3	ENSFCAP00000055336	ENSFCAP00000012234	Calmodulin 3; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.508
CALML3	CAV1	ENSFCAP00000027789	ENSFCAP00000029296	Calmodulin like 3; Belongs to the calmodulin family.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.914
CALML3	NOS3	ENSFCAP00000027789	ENSFCAP00000012234	Calmodulin like 3; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.948
CAV1	CALM1	ENSFCAP00000029296	ENSFCAP00000050555	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Uncharacterized protein; Belongs to the calmodulin family.	0.484
CAV1	CALM2	ENSFCAP00000029296	ENSFCAP00000016531	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Calmodulin 2; Belongs to the calmodulin family.	0.914
CAV1	CALM3	ENSFCAP00000029296	ENSFCAP00000055336	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Calmodulin 3; Belongs to the calmodulin family.	0.484
CAV1	CALML3	ENSFCAP00000029296	ENSFCAP00000027789	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	Calmodulin like 3; Belongs to the calmodulin family.	0.914