18 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HNF1B	HNF1 homeobox B. (558 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	NEUROD1	Neurogenic differentiation factor. (356 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	PAX6	Paired box 6. (437 aa)
	NKX2-2	NK2 homeobox 2. (273 aa)
	HNF1A	HNF1 homeobox A. (639 aa)
	FOXA2	Forkhead box A2. (457 aa)
	NEUROD4	Neurogenic differentiation factor. (331 aa)
	RFX6	Regulatory factor X6. (926 aa)
	FOXA3	Forkhead box A3. (350 aa)
	NEUROD2	Neurogenic differentiation factor. (382 aa)
	NKX6-1	NK6 homeobox 1. (367 aa)
	PDX1	Pancreatic and duodenal homeobox 1. (282 aa)
	FOXO1	Forkhead box O1. (662 aa)
	RFX4	Regulatory factor X4. (744 aa)
	NKX6-2	NK6 homeobox 2. (285 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	AKT3	ENSFCAP00000004586	ENSFCAP00000003410	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT1	FOXO1	ENSFCAP00000004586	ENSFCAP00000039549	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O1.	0.974
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	AKT3	ENSFCAP00000059662	ENSFCAP00000003410	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.918
AKT2	FOXO1	ENSFCAP00000059662	ENSFCAP00000039549	Non-specific serine/threonine protein kinase.	Forkhead box O1.	0.972
AKT3	AKT1	ENSFCAP00000003410	ENSFCAP00000004586	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT3	AKT2	ENSFCAP00000003410	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.918
AKT3	FOXO1	ENSFCAP00000003410	ENSFCAP00000039549	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O1.	0.968
FOXA2	HNF1A	ENSFCAP00000011475	ENSFCAP00000008940	Forkhead box A2.	HNF1 homeobox A.	0.452
FOXA2	NKX2-2	ENSFCAP00000011475	ENSFCAP00000008102	Forkhead box A2.	NK2 homeobox 2.	0.600
FOXA2	NKX6-1	ENSFCAP00000011475	ENSFCAP00000025113	Forkhead box A2.	NK6 homeobox 1.	0.718
FOXA2	PAX6	ENSFCAP00000011475	ENSFCAP00000006583	Forkhead box A2.	Paired box 6.	0.837
FOXA2	PDX1	ENSFCAP00000011475	ENSFCAP00000029882	Forkhead box A2.	Pancreatic and duodenal homeobox 1.	0.734
FOXA2	RFX6	ENSFCAP00000011475	ENSFCAP00000015694	Forkhead box A2.	Regulatory factor X6.	0.536
FOXA3	HNF1A	ENSFCAP00000017059	ENSFCAP00000008940	Forkhead box A3.	HNF1 homeobox A.	0.636
FOXA3	HNF1B	ENSFCAP00000017059	ENSFCAP00000000222	Forkhead box A3.	HNF1 homeobox B.	0.472
FOXA3	NKX2-2	ENSFCAP00000017059	ENSFCAP00000008102	Forkhead box A3.	NK2 homeobox 2.	0.437
FOXO1	AKT1	ENSFCAP00000039549	ENSFCAP00000004586	Forkhead box O1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.974
FOXO1	AKT2	ENSFCAP00000039549	ENSFCAP00000059662	Forkhead box O1.	Non-specific serine/threonine protein kinase.	0.972