33 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (548 aa)
	CYP4V2	Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa)
	POMC	Proopiomelanocortin. (258 aa)
	CYP21A2	Steroid 21-hydroxylase; Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. (494 aa)
	AHR	Uncharacterized protein. (849 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (486 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
	FDX2	2Fe-2S ferredoxin-type domain-containing protein. (186 aa)
	CYP7B1	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (510 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
	AHRR	Uncharacterized protein. (581 aa)
	CYP8B1	Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa)
	CYP19A1	Cytochrome P450 family 19 subfamily A polypeptide 1 transcript variant 1; Belongs to the cytochrome P450 family. (506 aa)
	NCOA2	Nuclear receptor coactivator. (1470 aa)
	LOC101098124	Uncharacterized protein. (508 aa)
	CYP51A1	Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa)
	FADS6	Fatty acid desaturase 6. (342 aa)
	CCDC160	Coiled-coil domain containing 160. (322 aa)
	FDX1	Ferredoxin 1. (186 aa)
	CYP39A1	Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (495 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (790 aa)
	PTGIS	Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
	NCOA1	Nuclear receptor coactivator. (1492 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (553 aa)
	ARNT2	Aryl hydrocarbon receptor nuclear translocator 2. (717 aa)
	FDXR	NADPH:adrenodoxin oxidoreductase, mitochondrial. (492 aa)
	ENSFCAP00000048958	BHLH domain-containing protein. (109 aa)
	RXRA	Retinoid X receptor alpha. (654 aa)
	LOC101097790	Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa)
	ENSFCAP00000054841	BHLH domain-containing protein. (262 aa)
	LOC101101073	Uncharacterized protein. (971 aa)
	ENSFCAP00000061174	Uncharacterized protein. (130 aa)
	CYP46A1	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (521 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	AHRR	ENSFCAP00000004645	ENSFCAP00000014308	Uncharacterized protein.	Uncharacterized protein.	0.549
AHR	ARNT	ENSFCAP00000004645	ENSFCAP00000037022	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.987
AHR	ARNT2	ENSFCAP00000004645	ENSFCAP00000044049	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.947
AHR	ENSFCAP00000048958	ENSFCAP00000004645	ENSFCAP00000048958	Uncharacterized protein.	BHLH domain-containing protein.	0.940
AHR	NCOA1	ENSFCAP00000004645	ENSFCAP00000042028	Uncharacterized protein.	Nuclear receptor coactivator.	0.518
AHR	NCOA2	ENSFCAP00000004645	ENSFCAP00000018792	Uncharacterized protein.	Nuclear receptor coactivator.	0.518
AHRR	AHR	ENSFCAP00000014308	ENSFCAP00000004645	Uncharacterized protein.	Uncharacterized protein.	0.549
AHRR	ARNT	ENSFCAP00000014308	ENSFCAP00000037022	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.941
AHRR	ARNT2	ENSFCAP00000014308	ENSFCAP00000044049	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.933
AHRR	CYP1B1	ENSFCAP00000014308	ENSFCAP00000042774	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.566
AHRR	ENSFCAP00000048958	ENSFCAP00000014308	ENSFCAP00000048958	Uncharacterized protein.	BHLH domain-containing protein.	0.724
AHRR	ENSFCAP00000054841	ENSFCAP00000014308	ENSFCAP00000054841	Uncharacterized protein.	BHLH domain-containing protein.	0.901
AHRR	NCOA1	ENSFCAP00000014308	ENSFCAP00000042028	Uncharacterized protein.	Nuclear receptor coactivator.	0.518
AHRR	NCOA2	ENSFCAP00000014308	ENSFCAP00000018792	Uncharacterized protein.	Nuclear receptor coactivator.	0.518
ARNT	AHR	ENSFCAP00000037022	ENSFCAP00000004645	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.987
ARNT	AHRR	ENSFCAP00000037022	ENSFCAP00000014308	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.941
ARNT	ARNT2	ENSFCAP00000037022	ENSFCAP00000044049	Aryl hydrocarbon receptor nuclear translocator.	Aryl hydrocarbon receptor nuclear translocator 2.	0.901
ARNT	CYP1B1	ENSFCAP00000037022	ENSFCAP00000042774	Aryl hydrocarbon receptor nuclear translocator.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.490
ARNT	ENSFCAP00000054841	ENSFCAP00000037022	ENSFCAP00000054841	Aryl hydrocarbon receptor nuclear translocator.	BHLH domain-containing protein.	0.836
ARNT	ENSFCAP00000061174	ENSFCAP00000037022	ENSFCAP00000061174	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.518