56 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNW1	SNW domain containing 1. (570 aa)
	TFDP2	Transcription factor. (386 aa)
	CCNQ	Cyclin Q; Belongs to the cyclin family. (376 aa)
	MKX	Mohawk homeobox. (454 aa)
	TGIF2LX	Homeobox domain-containing protein. (231 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (979 aa)
	E2F4	E2F transcription factor 4. (406 aa)
	UBA52	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
	SP1	Sp1 transcription factor. (786 aa)
	JUNB	JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
	RBL1	RB transcriptional corepressor like 1. (1068 aa)
	RPS27A	Ribosomal protein S27a. (156 aa)
	IRX4	Iroquois homeobox 4. (520 aa)
	SMURF2	E3 ubiquitin-protein ligase. (748 aa)
	SKI	SKI proto-oncogene. (730 aa)
	TGIF2	TGFB induced factor homeobox 2. (237 aa)
	TGIF1	TGFB induced factor homeobox 1. (272 aa)
	NCOR2	Nuclear receptor corepressor 2. (2458 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
	ENSFCAP00000026617	Ubiquitin-like domain-containing protein. (78 aa)
	USP9X	Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa)
	CDK9	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (492 aa)
	IRX6	Iroquois homeobox 6. (451 aa)
	RNF111	Ring finger protein 111. (1002 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	MEIS3	Homeobox domain-containing protein. (377 aa)
	IRX3	Iroquois homeobox 3. (502 aa)
	CCNC	Cyclin C; Belongs to the cyclin family. (283 aa)
	LOC109502223	Ubiquitin-like domain-containing protein. (176 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa)
	NCOR1	Nuclear receptor corepressor 1. (2515 aa)
	SMAD3	Mothers against decapentaplegic homolog. (457 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	WWTR1	WW domain containing transcription regulator 1. (400 aa)
	SKIL	SKI like proto-oncogene. (686 aa)
	KXD1	KxDL motif containing 1. (201 aa)
	CDK19	Cyclin dependent kinase 19. (502 aa)
	CCNK	Cyclin K; Belongs to the cyclin family. (582 aa)
	TRIM33	Tripartite motif containing 33. (1127 aa)
	SMAD7	Mothers against decapentaplegic homolog. (426 aa)
	IRX5	Iroquois homeobox 5. (483 aa)
	IRX2	Iroquois homeobox 2. (456 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
	CDK8	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
	CCNT1	CYCLIN domain-containing protein; Belongs to the cyclin family. (184 aa)
	IRX1	Iroquois homeobox 1. (485 aa)
	TFDP1	Transcription factor. (423 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (825 aa)
	MEN1	Menin 1. (749 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (486 aa)
	UBE2D1	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	NEDD4L	NEDD4 like E3 ubiquitin protein ligase. (1246 aa)
	CCNT2	Cyclin T2; Belongs to the cyclin family. (742 aa)
	SMAD2	Mothers against decapentaplegic homolog. (721 aa)
	FURIN	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (877 aa)
	CA13	Carbonic anhydrase 13. (534 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B4	MAPK1	ENSFCAP00000045955	ENSFCAP00000025541	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase; Belongs to the PP2C family.	0.900
ATP1B4	MAPK3	ENSFCAP00000045955	ENSFCAP00000034399	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.900
ATP1B4	SNW1	ENSFCAP00000045955	ENSFCAP00000001520	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SNW domain containing 1.	0.930
CA13	E2F4	ENSFCAP00000062084	ENSFCAP00000008592	Carbonic anhydrase 13.	E2F transcription factor 4.	0.956
CA13	HDAC1	ENSFCAP00000062084	ENSFCAP00000033351	Carbonic anhydrase 13.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.507
CA13	RBL1	ENSFCAP00000062084	ENSFCAP00000017521	Carbonic anhydrase 13.	RB transcriptional corepressor like 1.	0.991
CA13	SMAD2	ENSFCAP00000062084	ENSFCAP00000057862	Carbonic anhydrase 13.	Mothers against decapentaplegic homolog.	0.949
CA13	SMAD3	ENSFCAP00000062084	ENSFCAP00000034334	Carbonic anhydrase 13.	Mothers against decapentaplegic homolog.	0.628
CA13	SMAD4	ENSFCAP00000062084	ENSFCAP00000031311	Carbonic anhydrase 13.	Mothers against decapentaplegic homolog.	0.968
CA13	TFDP1	ENSFCAP00000062084	ENSFCAP00000049530	Carbonic anhydrase 13.	Transcription factor.	0.984
CA13	TFDP2	ENSFCAP00000062084	ENSFCAP00000002843	Carbonic anhydrase 13.	Transcription factor.	0.980
CCNC	CCNK	ENSFCAP00000032479	ENSFCAP00000041763	Cyclin C; Belongs to the cyclin family.	Cyclin K; Belongs to the cyclin family.	0.730
CCNC	CCNQ	ENSFCAP00000032479	ENSFCAP00000003723	Cyclin C; Belongs to the cyclin family.	Cyclin Q; Belongs to the cyclin family.	0.505
CCNC	CCNT1	ENSFCAP00000032479	ENSFCAP00000048125	Cyclin C; Belongs to the cyclin family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.634
CCNC	CCNT2	ENSFCAP00000032479	ENSFCAP00000055801	Cyclin C; Belongs to the cyclin family.	Cyclin T2; Belongs to the cyclin family.	0.632
CCNC	CDK19	ENSFCAP00000032479	ENSFCAP00000041224	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 19.	0.999
CCNC	CDK8	ENSFCAP00000032479	ENSFCAP00000048044	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	0.999
CCNC	CDK9	ENSFCAP00000032479	ENSFCAP00000028744	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.	0.870
CCNC	SMAD4	ENSFCAP00000032479	ENSFCAP00000031311	Cyclin C; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.484
CCNK	CCNC	ENSFCAP00000041763	ENSFCAP00000032479	Cyclin K; Belongs to the cyclin family.	Cyclin C; Belongs to the cyclin family.	0.730