STRINGSTRING
METAP1 METAP1 GRK1 GRK1 GNAT1 GNAT1 PDE6B PDE6B CNGA1 CNGA1 GRK7 GRK7 CAMKMT CAMKMT SAG SAG PDE6G PDE6G GUCA1A GUCA1A RGS9 RGS9 GUCY2D GUCY2D CALM2 CALM2 M3WQU5_FELCA M3WQU5_FELCA FNTA FNTA LOC101099582 LOC101099582 GNGT1 GNGT1 NMT2 NMT2 PDE6C PDE6C RCVRN RCVRN FNTB FNTB GUCY2F GUCY2F PPEF1 PPEF1 CALML3 CALML3 CNGB3 CNGB3 LOC101097703 LOC101097703 ENSFCAP00000029012 ENSFCAP00000029012 CHURC1 CHURC1 METAP2 METAP2 VEZT VEZT PDE6A PDE6A GUCA1B GUCA1B RGS9BP RGS9BP CALM1 CALM1 GUCA1C GUCA1C CALM3 CALM3 PDE6H PDE6H GNB5 GNB5 ENSFCAP00000060347 ENSFCAP00000060347 NMT1 NMT1 PPEF2 PPEF2 RHO RHO CNGB1 CNGB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
METAP1Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (386 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
GNAT1G protein subunit alpha transducin 1. (350 aa)
PDE6BPhosphodiesterase. (880 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (695 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
CAMKMTCalmodulin-lysine N-methyltransferase. (323 aa)
SAGS-antigen visual arrestin. (407 aa)
PDE6GRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones (By similarity). (87 aa)
GUCA1AGuanylate cyclase activator 1A. (275 aa)
RGS9Regulator of G protein signaling 9. (668 aa)
GUCY2DGuanylate cyclase. (1100 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
M3WQU5_FELCAEF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa)
FNTAFarnesyltransferase, CAAX box, alpha. (452 aa)
LOC101099582Guanylate cyclase. (1118 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
NMT2Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (530 aa)
PDE6CPhosphodiesterase. (846 aa)
RCVRNRecoverin. (338 aa)
FNTBProtein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. (437 aa)
GUCY2FGuanylate cyclase. (1108 aa)
PPEF1Serine/threonine-protein phosphatase with EF-hands. (660 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
CNGB3Cyclic nucleotide gated channel subunit beta 3. (807 aa)
LOC101097703EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
ENSFCAP00000029012Uncharacterized protein; Belongs to the calmodulin family. (124 aa)
CHURC1Churchill domain containing 1. (112 aa)
METAP2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (478 aa)
VEZTVezatin, adherens junctions transmembrane protein. (785 aa)
PDE6APhosphodiesterase. (861 aa)
GUCA1BGuanylate cyclase activator 1B. (201 aa)
RGS9BPRegulator of G protein signaling 9 binding protein. (235 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (192 aa)
GUCA1CGuanylate cyclase activator 1C. (210 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (276 aa)
PDE6HUncharacterized protein. (122 aa)
GNB5G protein subunit beta 5. (403 aa)
ENSFCAP00000060347Uncharacterized protein; Belongs to the calmodulin family. (146 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (539 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (752 aa)
RHORhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity). (348 aa)
CNGB1Cyclic nucleotide-binding domain-containing protein. (1204 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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