STRINGSTRING
MED26 MED26 ENSFCAP00000051748 ENSFCAP00000051748 FAM120B FAM120B PPARGC1A PPARGC1A BCLAF1 BCLAF1 MED8 MED8 MAP7 MAP7 MAP7D1 MAP7D1 MED7 MED7 KLF5 KLF5 NCOR2 NCOR2 MED11 MED11 MAP7D2 MAP7D2 THRAP3 THRAP3 NCOR1 NCOR1 EBF4 EBF4 MED13L MED13L HDAC3 HDAC3 MED22 MED22 MAP7D3 MAP7D3 ZNF638 ZNF638 MED9 MED9 EBF1 EBF1 MED21 MED21 CEBPD CEBPD EBF3 EBF3 EBF2 EBF2 PLIN1 PLIN1 MED29 MED29 MED19 MED19 RXRA RXRA ADIRF ADIRF PPARG PPARG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED26TFIIS N-terminal domain-containing protein. (629 aa)
ENSFCAP00000051748Uncharacterized protein. (59 aa)
FAM120BFamily with sequence similarity 120B. (957 aa)
PPARGC1APPARG coactivator 1 alpha. (803 aa)
BCLAF1Uncharacterized protein. (948 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (302 aa)
MAP7Microtubule associated protein 7. (773 aa)
MAP7D1MAP7 domain containing 1. (843 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (233 aa)
KLF5Kruppel like factor 5. (457 aa)
NCOR2Nuclear receptor corepressor 2. (2458 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
MAP7D2MAP7 domain containing 2. (792 aa)
THRAP3Thyroid hormone receptor associated protein 3. (958 aa)
NCOR1Nuclear receptor corepressor 1. (2515 aa)
EBF4EBF family member 4. (875 aa)
MED13LMediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2177 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
MED22Mediator complex subunit 22. (200 aa)
MAP7D3MAP7 domain containing 3. (864 aa)
ZNF638Zinc finger protein 638. (1973 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (147 aa)
EBF1EBF transcription factor 1. (591 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa)
CEBPDCCAAT/enhancer-binding protein. (273 aa)
EBF3EBF transcription factor 3. (620 aa)
EBF2EBF transcription factor 2. (575 aa)
PLIN1Perilipin; Belongs to the perilipin family. (522 aa)
MED29Mediator complex subunit 29. (220 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
RXRARetinoid X receptor alpha. (654 aa)
ADIRFAdipogenesis regulatory factor. (76 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]