STRINGSTRING
PAK3 PAK3 MTOR MTOR PDPK1 PDPK1 CEP170 CEP170 PTK6 PTK6 FNDC3B FNDC3B MLST8 MLST8 THEM4 THEM4 AKT3 AKT3 PAK1 PAK1 MAP3K8 MAP3K8 CDC42 CDC42 AKT1 AKT1 VAV1 VAV1 SRMS SRMS CD80 CD80 PIK3R1 PIK3R1 GRAP2 GRAP2 MAP3K14 MAP3K14 CD28 CD28 PAK2 PAK2 FNDC3A FNDC3A FYN FYN LYN LYN GRB2 GRB2 CDC42-2 CDC42-2 AKT2 AKT2 CD86 CD86 ENSFCAP00000054708 ENSFCAP00000054708 ENSFCAP00000052091 ENSFCAP00000052091 RICTOR RICTOR YES1 YES1 PIK3R3 PIK3R3 PRR5 PRR5 PIK3R2 PIK3R2 SRC SRC MAPKAP1 MAPKAP1 CD276 CD276 PIK3CA PIK3CA TRIB3 TRIB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAK3P21 (RAC1) activated kinase 3. (589 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
CEP170Centrosomal protein 170. (1588 aa)
PTK6Tyrosine-protein kinase. (450 aa)
FNDC3BFibronectin type III domain containing 3B. (1207 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
THEM4Thioesterase superfamily member 4. (238 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
CDC42Uncharacterized protein. (191 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
SRMSTyrosine-protein kinase. (507 aa)
CD80B-lymphocyte activation antigen B7-1 (CD80). (292 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
GRAP2GRB2 related adaptor protein 2. (322 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (954 aa)
CD28T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. (255 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
FNDC3AFibronectin type III domain containing 3A. (1199 aa)
FYNTyrosine-protein kinase. (589 aa)
LYNTyrosine-protein kinase. (526 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CDC42-2Uncharacterized protein. (191 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
CD86B-lymphocyte activation antigen B7-2 (CD86). (332 aa)
ENSFCAP00000054708Uncharacterized protein. (102 aa)
ENSFCAP00000052091Uncharacterized protein. (1125 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
YES1Tyrosine-protein kinase. (546 aa)
PIK3R3Uncharacterized protein. (461 aa)
PRR5Proline rich 5. (389 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
SRCTyrosine-protein kinase. (678 aa)
MAPKAP1MAPK associated protein 1. (575 aa)
CD276CD276 molecule. (669 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
TRIB3Tribbles pseudokinase 3. (357 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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