63 items (Felis catus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ENSFCAP00000055519	Uncharacterized protein. (556 aa)
	LMOD1	Leiomodin 1. (579 aa)
	MYL6	Myosin light chain 6. (161 aa)
	PAK1	Non-specific serine/threonine protein kinase. (544 aa)
	SORBS3	Sorbin and SH3 domain containing 3. (676 aa)
	TRIM72	Tripartite motif containing 72. (477 aa)
	TLN2	Talin 2. (2542 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (464 aa)
	TPM4	Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
	MYOF	Myoferlin. (2080 aa)
	CACNA1G	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2375 aa)
	TPM2	Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)
	TLN1	Talin 1. (2558 aa)
	MARF1	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1980 aa)
	CACNA1I	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2184 aa)
	MYLPF	Myosin light chain, phosphorylatable, fast skeletal muscle. (170 aa)
	M3WKD8_FELCA	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (715 aa)
	MYL6B	Myosin light chain 6B. (211 aa)
	MYZAP	Uncharacterized protein. (463 aa)
	MYL5	Myosin light chain 5. (174 aa)
	CACNA1H	Calcium voltage-gated channel subunit alpha1 H. (2240 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	M3WQU5_FELCA	EF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	M3WUF6_FELCA	Uncharacterized protein. (98 aa)
	ALDH2	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (517 aa)
	VCL	Vinculin. (1066 aa)
	MYL9	Myosin light chain 9. (172 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	ENSFCAP00000028191	Uncharacterized protein. (552 aa)
	SPEGNB	SPEG neighbor. (238 aa)
	LOC101097703	EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
	ENSFCAP00000029012	Uncharacterized protein; Belongs to the calmodulin family. (124 aa)
	MYL10	Myosin light chain 10. (167 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (800 aa)
	PDE5A	Phosphodiesterase. (865 aa)
	DYSF	Dysferlin. (2112 aa)
	PXN	Paxillin. (1089 aa)
	CALD1	Caldesmon 1. (831 aa)
	SORBS2	Sorbin and SH3 domain containing 2. (1504 aa)
	GUCY1A1	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
	MYL12A	Myosin light chain 12A. (178 aa)
	ENSFCAP00000041015	Uncharacterized protein. (229 aa)
	TPM3	Tropomyosin 3; Belongs to the tropomyosin family. (334 aa)
	GUCY1B1	Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (618 aa)
	MYLK	Uncharacterized protein. (1920 aa)
	TPM1	Tropomyosin 1; Belongs to the tropomyosin family. (336 aa)
	MYL7	Myosin light chain 7. (216 aa)
	FER1L5	Fer-1 like family member 5. (2051 aa)
	TLNRD1	Talin rod domain containing 1. (363 aa)
	CALM1	Uncharacterized protein; Belongs to the calmodulin family. (192 aa)
	TTN	Titin. (27108 aa)
	ENSFCAP00000051882	EF-hand domain-containing protein. (130 aa)
	GUCY1A2	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (791 aa)
	SORBS1	Sorbin and SH3 domain containing 1. (1525 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (276 aa)
	LPXN	Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (387 aa)
	ENSFCAP00000058078	Uncharacterized protein. (545 aa)
	ENSFCAP00000058156	Uncharacterized protein. (552 aa)
	ENSFCAP00000060347	Uncharacterized protein; Belongs to the calmodulin family. (146 aa)
	ENSFCAP00000060514	Uncharacterized protein. (135 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNA1G	CACNA1H	ENSFCAP00000011451	ENSFCAP00000015849	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Calcium voltage-gated channel subunit alpha1 H.	0.921
CACNA1G	CACNA1I	ENSFCAP00000011451	ENSFCAP00000012525	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.923
CACNA1G	CALM2	ENSFCAP00000011451	ENSFCAP00000016531	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Calmodulin 2; Belongs to the calmodulin family.	0.913
CACNA1G	CALML3	ENSFCAP00000011451	ENSFCAP00000027789	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Calmodulin like 3; Belongs to the calmodulin family.	0.913
CACNA1G	LOC101097703	ENSFCAP00000011451	ENSFCAP00000028786	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	EF-hand domain-containing protein; Belongs to the calmodulin family.	0.913
CACNA1H	CACNA1G	ENSFCAP00000015849	ENSFCAP00000011451	Calcium voltage-gated channel subunit alpha1 H.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.921
CACNA1H	CACNA1I	ENSFCAP00000015849	ENSFCAP00000012525	Calcium voltage-gated channel subunit alpha1 H.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.925
CACNA1H	CALM2	ENSFCAP00000015849	ENSFCAP00000016531	Calcium voltage-gated channel subunit alpha1 H.	Calmodulin 2; Belongs to the calmodulin family.	0.913
CACNA1H	CALML3	ENSFCAP00000015849	ENSFCAP00000027789	Calcium voltage-gated channel subunit alpha1 H.	Calmodulin like 3; Belongs to the calmodulin family.	0.913
CACNA1H	CAV3	ENSFCAP00000015849	ENSFCAP00000030878	Calcium voltage-gated channel subunit alpha1 H.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.429
CACNA1H	ENSFCAP00000060514	ENSFCAP00000015849	ENSFCAP00000060514	Calcium voltage-gated channel subunit alpha1 H.	Uncharacterized protein.	0.897
CACNA1H	LOC101097703	ENSFCAP00000015849	ENSFCAP00000028786	Calcium voltage-gated channel subunit alpha1 H.	EF-hand domain-containing protein; Belongs to the calmodulin family.	0.913
CACNA1I	CACNA1G	ENSFCAP00000012525	ENSFCAP00000011451	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.923
CACNA1I	CACNA1H	ENSFCAP00000012525	ENSFCAP00000015849	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Calcium voltage-gated channel subunit alpha1 H.	0.925
CACNA1I	CALM2	ENSFCAP00000012525	ENSFCAP00000016531	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Calmodulin 2; Belongs to the calmodulin family.	0.913
CACNA1I	CALML3	ENSFCAP00000012525	ENSFCAP00000027789	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Calmodulin like 3; Belongs to the calmodulin family.	0.913
CACNA1I	CAV3	ENSFCAP00000012525	ENSFCAP00000030878	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.453
CACNA1I	LOC101097703	ENSFCAP00000012525	ENSFCAP00000028786	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	EF-hand domain-containing protein; Belongs to the calmodulin family.	0.913
CALD1	ITGA1	ENSFCAP00000037083	ENSFCAP00000031172	Caldesmon 1.	Integrin subunit alpha 1; Belongs to the integrin alpha chain family.	0.428
CALD1	ITGB5	ENSFCAP00000037083	ENSFCAP00000034245	Caldesmon 1.	Integrin beta; Belongs to the integrin beta chain family.	0.426