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TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) | ||||
PSMD6 | Proteasome 26S subunit, non-ATPase 6. (478 aa) | ||||
PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) | ||||
PSMD8 | Proteasome 26S subunit, non-ATPase 8. (355 aa) | ||||
PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) | ||||
NFKB2 | Nuclear factor kappa B subunit 2. (921 aa) | ||||
PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) | ||||
APP | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (935 aa) | ||||
PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) | ||||
NLRP9 | NLR family pyrin domain containing 9. (990 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) | ||||
GZMB | Granzyme B; Belongs to the peptidase S1 family. (255 aa) | ||||
NLRC5 | NLR family CARD domain containing 5. (1844 aa) | ||||
PTPN21 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1167 aa) | ||||
NFKBIB | NFKB inhibitor beta. (354 aa) | ||||
PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) | ||||
UBE2N | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) | ||||
LRRC31 | Leucine rich repeat containing 31. (566 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (492 aa) | ||||
PSME1 | Proteasome activator subunit 1. (249 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (314 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (989 aa) | ||||
SIGIRR | Single Ig and TIR domain containing. (410 aa) | ||||
PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) | ||||
IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). (270 aa) | ||||
PELI2 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (464 aa) | ||||
IL33 | Interleukin 33. (268 aa) | ||||
UBA52 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa) | ||||
ALPK1 | Alpha kinase 1. (1239 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (724 aa) | ||||
IRAK2 | Interleukin 1 receptor associated kinase 2. (618 aa) | ||||
TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) | ||||
PSMA1 | Proteasome subunit alpha type. (263 aa) | ||||
LRRC45 | Leucine rich repeat containing 45. (670 aa) | ||||
TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa) | ||||
IL1R2 | Interleukin 1 receptor type 2. (418 aa) | ||||
IL1R1 | Interleukin 1 receptor type 1. (572 aa) | ||||
PSMB10 | Proteasome subunit beta. (273 aa) | ||||
LOC101099215 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (292 aa) | ||||
S100A12 | EF-hand domain-containing protein; Belongs to the S-100 family. (92 aa) | ||||
TONSL | Tonsoku like, DNA repair protein. (1370 aa) | ||||
LRRC14 | Leucine rich repeat containing 14. (503 aa) | ||||
PSMB7 | Proteasome subunit beta. (277 aa) | ||||
SQSTM1 | Sequestosome 1. (443 aa) | ||||
PTPN23 | Protein tyrosine phosphatase non-receptor type 23. (1658 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
IL1RAP | Interleukin 1 receptor accessory protein. (639 aa) | ||||
IL18RAP | Interleukin 18 receptor accessory protein. (586 aa) | ||||
PSMD9 | Proteasome 26S subunit, non-ATPase 9. (284 aa) | ||||
PSMB11 | Proteasome subunit beta. (276 aa) | ||||
IL1RL1 | Interleukin 1 receptor like 1. (556 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) | ||||
PTPN14 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (251 aa) | ||||
NLRP6 | NLR family pyrin domain containing 6. (878 aa) | ||||
RPS27A | Ribosomal protein S27a. (156 aa) | ||||
IRAK4 | Interleukin 1 receptor associated kinase 4. (492 aa) | ||||
IL1RL2 | Interleukin 1 receptor like 2. (554 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (423 aa) | ||||
LOC101083848 | Proteasome subunit beta. (209 aa) | ||||
PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) | ||||
PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) | ||||
TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa) | ||||
RBX1 | Ring-box 1. (108 aa) | ||||
PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) | ||||
PSMA2 | Proteasome subunit alpha type. (234 aa) | ||||
CUL1 | Cullin 1; Belongs to the cullin family. (829 aa) | ||||
LRRC71 | Leucine rich repeat containing 71. (556 aa) | ||||
N4BP1 | NEDD4 binding protein 1. (896 aa) | ||||
PSMA8 | Proteasome subunit alpha type. (250 aa) | ||||
LOC101083171 | Proteasome subunit beta. (276 aa) | ||||
IL36RN | Interleukin-1. (196 aa) | ||||
KHNYN | KH and NYN domain containing. (677 aa) | ||||
ENSFCAP00000026617 | Ubiquitin-like domain-containing protein. (78 aa) | ||||
PSMB6 | Proteasome subunit beta. (239 aa) | ||||
ENSFCAP00000026978 | Uncharacterized protein. (111 aa) | ||||
PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (192 aa) | ||||
TNIP2 | TNFAIP3 interacting protein 2. (436 aa) | ||||
MAP3K3 | Uncharacterized protein. (626 aa) | ||||
LOC101099075 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) | ||||
IL18BP | Interleukin 18 binding protein. (183 aa) | ||||
LOC109502223 | Ubiquitin-like domain-containing protein. (176 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (241 aa) | ||||
ENSFCAP00000034079 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (108 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (457 aa) | ||||
ENSFCAP00000034335 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (104 aa) | ||||
PSMF1 | Proteasome inhibitor subunit 1. (341 aa) | ||||
IL13 | Interleukin 13. (144 aa) | ||||
PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) | ||||
S100B | Protein S100; Belongs to the S-100 family. (92 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (308 aa) | ||||
ENSFCAP00000036869 | Proteasome subunit alpha type. (197 aa) | ||||
NLRX1 | NLR family member X1. (975 aa) | ||||
KXD1 | KxDL motif containing 1. (201 aa) | ||||
IL18R1 | Interleukin 18 receptor 1. (539 aa) | ||||
IL1RAPL1 | Interleukin 1 receptor accessory protein like 1. (696 aa) | ||||
LOC111556170 | Proteasome subunit beta type-8. (276 aa) | ||||
BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) | ||||
IL1F10 | Interleukin-1. (152 aa) | ||||
LOC111556171 | Uncharacterized protein. (234 aa) | ||||
ENSFCAP00000041674 | AAA domain-containing protein; Belongs to the AAA ATPase family. (189 aa) | ||||
LOC101099498 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (129 aa) | ||||
PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa) | ||||
PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) | ||||
TOLLIP | Toll interacting protein. (306 aa) | ||||
PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa) | ||||
NKIRAS2 | Uncharacterized protein. (41 aa) | ||||
MFSD1 | Major facilitator superfamily domain containing 1. (468 aa) | ||||
MAP3K20 | Uncharacterized protein. (800 aa) | ||||
PSMA4 | Proteasome subunit alpha type. (277 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) | ||||
PSME4 | Proteasome activator subunit 4. (1865 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) | ||||
LOC101082405 | AAA domain-containing protein. (330 aa) | ||||
PSMD4 | Proteasome 26S subunit, non-ATPase 4. (423 aa) | ||||
PSMB5 | Proteasome subunit beta. (263 aa) | ||||
VWC2 | Von Willebrand factor C domain containing 2. (333 aa) | ||||
LOC105260043 | Uncharacterized protein. (391 aa) | ||||
IL1RN | Interleukin-1. (182 aa) | ||||
PTPN5 | Protein tyrosine phosphatase non-receptor type 5. (593 aa) | ||||
SAA1 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (163 aa) | ||||
CTSG | Cathepsin G; Belongs to the peptidase S1 family. (292 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) | ||||
TIFA | FHA domain-containing protein. (381 aa) | ||||
PSME2 | Proteasome activator subunit 2. (253 aa) | ||||
PSME3 | Uncharacterized protein. (265 aa) | ||||
PSMB1 | Proteasome subunit beta. (261 aa) | ||||
ENSFCAP00000053469 | PA28_beta domain-containing protein. (192 aa) | ||||
CCDC71L | Coiled-coil domain containing 71 like. (238 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (258 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (479 aa) | ||||
ENSFCAP00000055272 | Uncharacterized protein; Belongs to the SKP1 family. (147 aa) | ||||
IL36G | Interleukin-1. (219 aa) | ||||
PTPN20 | Protein tyrosine phosphatase non-receptor type 20. (446 aa) | ||||
TMEM189 | Transmembrane protein 189. (296 aa) | ||||
USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa) | ||||
PSMA7 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (358 aa) | ||||
NKIRAS1 | NFKB inhibitor interacting Ras like 1. (289 aa) | ||||
LRRC34 | Leucine rich repeat containing 34. (513 aa) | ||||
HMGB1 | Uncharacterized protein. (233 aa) | ||||
LRRC74A | Leucine rich repeat containing 74A. (505 aa) | ||||
GSDMD | Gasdermin D. (531 aa) | ||||
PSMB2 | Proteasome subunit beta. (201 aa) | ||||
PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa) | ||||
USP18 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (403 aa) | ||||
PSMB3 | Proteasome subunit beta. (268 aa) | ||||
SKP1 | Uncharacterized protein; Belongs to the SKP1 family. (168 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (774 aa) | ||||
IRAK3 | Interleukin 1 receptor associated kinase 3. (551 aa) | ||||
PSMD3 | Proteasome 26S subunit, non-ATPase 3. (595 aa) |