21 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EXOSC7	Exosome component 7. (441 aa)
	EXOSC5	Exosome component 5. (235 aa)
	EXOSC3	Exosome component 3. (450 aa)
	EXOSC4	Exosome component 4. (245 aa)
	ENSFCAP00000040149	Uncharacterized protein. (79 aa)
	DIS3	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
	XRN1	5'-3' exoribonuclease 1. (1707 aa)
	EXOSC1	Exosome component 1. (215 aa)
	EXOSC6	Exosome component 6. (272 aa)
	EXOSC8	Exosome component 8. (298 aa)
	DIS3L2	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (1028 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)
	DCP2	Decapping mRNA 2. (422 aa)
	DCP1A	Decapping mRNA 1A. (580 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	MAPKAPK2	MAPK activated protein kinase 2. (409 aa)
	DIS3L	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1027 aa)
	EXOSC2	Exosome component 2. (293 aa)
	ZFP36L1	ZFP36 ring finger protein like 1. (338 aa)
	EXOSC9	Exosome component 9. (261 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	ZFP36L1	ENSFCAP00000004586	ENSFCAP00000023831	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	ZFP36 ring finger protein like 1.	0.572
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	ZFP36L1	ENSFCAP00000059662	ENSFCAP00000023831	Non-specific serine/threonine protein kinase.	ZFP36 ring finger protein like 1.	0.572
DCP1A	DCP2	ENSFCAP00000003600	ENSFCAP00000001753	Decapping mRNA 1A.	Decapping mRNA 2.	0.999
DCP1A	DIS3	ENSFCAP00000003600	ENSFCAP00000046298	Decapping mRNA 1A.	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.631
DCP1A	DIS3L	ENSFCAP00000003600	ENSFCAP00000017761	Decapping mRNA 1A.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.579
DCP1A	DIS3L2	ENSFCAP00000003600	ENSFCAP00000054121	Decapping mRNA 1A.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.549
DCP1A	ENSFCAP00000040149	ENSFCAP00000003600	ENSFCAP00000040149	Decapping mRNA 1A.	Uncharacterized protein.	0.556
DCP1A	EXOSC1	ENSFCAP00000003600	ENSFCAP00000048590	Decapping mRNA 1A.	Exosome component 1.	0.576
DCP1A	EXOSC2	ENSFCAP00000003600	ENSFCAP00000023183	Decapping mRNA 1A.	Exosome component 2.	0.629
DCP1A	EXOSC3	ENSFCAP00000003600	ENSFCAP00000030207	Decapping mRNA 1A.	Exosome component 3.	0.615
DCP1A	EXOSC4	ENSFCAP00000003600	ENSFCAP00000034996	Decapping mRNA 1A.	Exosome component 4.	0.657
DCP1A	EXOSC5	ENSFCAP00000003600	ENSFCAP00000030471	Decapping mRNA 1A.	Exosome component 5.	0.657
DCP1A	EXOSC6	ENSFCAP00000003600	ENSFCAP00000048839	Decapping mRNA 1A.	Exosome component 6.	0.610
DCP1A	EXOSC9	ENSFCAP00000003600	ENSFCAP00000025320	Decapping mRNA 1A.	Exosome component 9.	0.556
DCP1A	XRN1	ENSFCAP00000003600	ENSFCAP00000047866	Decapping mRNA 1A.	5'-3' exoribonuclease 1.	0.995
DCP1A	ZFP36L1	ENSFCAP00000003600	ENSFCAP00000023831	Decapping mRNA 1A.	ZFP36 ring finger protein like 1.	0.583
DCP2	DCP1A	ENSFCAP00000001753	ENSFCAP00000003600	Decapping mRNA 2.	Decapping mRNA 1A.	0.999
DCP2	DIS3	ENSFCAP00000001753	ENSFCAP00000046298	Decapping mRNA 2.	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.689