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PSME1 PSME1 NUP214 NUP214 PSMD3 PSMD3 AKT2 AKT2 PSMB3 PSMB3 PSMC6 PSMC6 PSMB2 PSMB2 PABPC4 PABPC4 KHSRP KHSRP PSMA7 PSMA7 ENSFCAP00000056600 ENSFCAP00000056600 ENSFCAP00000056245 ENSFCAP00000056245 PSMA3 PSMA3 DIS3L2 DIS3L2 EXOSC8 EXOSC8 ENSFCAP00000053469 ENSFCAP00000053469 PSMB1 PSMB1 LOC101093782 LOC101093782 PSME3 PSME3 PSME2 PSME2 PSMD1 PSMD1 EXOSC6 EXOSC6 HNRNPD HNRNPD PSMB5 PSMB5 FUBP1 FUBP1 PSMD4 PSMD4 EXOSC1 EXOSC1 LOC101082405 LOC101082405 PSME4 PSME4 XRN1 XRN1 PSMA4 PSMA4 ZFP36 ZFP36 DIS3 DIS3 ZFP36L2 ZFP36L2 PARN PARN PSMD14 PSMD14 PSMC3 PSMC3 TNPO1 TNPO1 ENSFCAP00000041674 ENSFCAP00000041674 LOC111556171 LOC111556171 PABPC1 PABPC1 LOC111556170 LOC111556170 ENSFCAP00000040149 ENSFCAP00000040149 PABPC1L PABPC1L HSPA8 HSPA8 KXD1 KXD1 ENSFCAP00000036869 ENSFCAP00000036869 ANP32A ANP32A ELAVL2 ELAVL2 PSMC1 PSMC1 TOE1 TOE1 EXOSC4 EXOSC4 PSMF1 PSMF1 PSMA5 PSMA5 ENSFCAP00000033387 ENSFCAP00000033387 PABPC4L PABPC4L LOC109502223 LOC109502223 ELAVL4 ELAVL4 EXOSC5 EXOSC5 EXOSC3 EXOSC3 ELAVL1 ELAVL1 ENSFCAP00000026978 ENSFCAP00000026978 PSMB6 PSMB6 ENSFCAP00000026617 ENSFCAP00000026617 EXOSC7 EXOSC7 EXOSC9 EXOSC9 LOC101083171 LOC101083171 PSMA8 PSMA8 ZFP36L1 ZFP36L1 PSMA2 PSMA2 PSMD11 PSMD11 EXOSC2 EXOSC2 TSPYL5 TSPYL5 HNRNPAB HNRNPAB PSMD10 PSMD10 PSMD12 PSMD12 LOC101083848 LOC101083848 HSPB1 HSPB1 RPS27A RPS27A YWHAZ YWHAZ PSMA6 PSMA6 ANP32E ANP32E DIS3L DIS3L PSMD7 PSMD7 ELAVL3 ELAVL3 PSMB11 PSMB11 PSMD9 PSMD9 TSPYL4 TSPYL4 ANP32B ANP32B PSMB7 PSMB7 MAPKAPK2 MAPKAPK2 PSMB10 PSMB10 PRKCA PRKCA M3WFK5_FELCA M3WFK5_FELCA YWHAB YWHAB PSMA1 PSMA1 UBA52 UBA52 EIF4G1 EIF4G1 PSMD2 PSMD2 M3W518_FELCA M3W518_FELCA SET SET FUBP3 FUBP3 AKT1 AKT1 DCP1A DCP1A PRKCD PRKCD PSMC5 PSMC5 PNLDC1 PNLDC1 XPO1 XPO1 PSMD13 PSMD13 DCP2 DCP2 PSMB4 PSMB4 PSMD5 PSMD5 PSMC4 PSMC4 PSMD8 PSMD8 PSMC2 PSMC2 PSMD6 PSMD6 TNPO2 TNPO2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSME1Proteasome activator subunit 1. (249 aa)
NUP214Nucleoporin 214. (1521 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (595 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
PSMB3Proteasome subunit beta. (268 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa)
PSMB2Proteasome subunit beta. (201 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (700 aa)
KHSRPKH-type splicing regulatory protein. (727 aa)
PSMA7Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (358 aa)
ENSFCAP00000056600ANAPC4_WD40 domain-containing protein. (281 aa)
ENSFCAP0000005624514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (178 aa)
PSMA3Proteasome subunit alpha type. (258 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (1028 aa)
EXOSC8Exosome component 8. (298 aa)
ENSFCAP00000053469PA28_beta domain-containing protein. (192 aa)
PSMB1Proteasome subunit beta. (261 aa)
LOC101093782Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (272 aa)
PSME3Uncharacterized protein. (265 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
EXOSC6Exosome component 6. (272 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (534 aa)
PSMB5Proteasome subunit beta. (263 aa)
FUBP1Far upstream element binding protein 1. (687 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (423 aa)
EXOSC1Exosome component 1. (215 aa)
LOC101082405AAA domain-containing protein. (330 aa)
PSME4Proteasome activator subunit 4. (1865 aa)
XRN15'-3' exoribonuclease 1. (1707 aa)
PSMA4Proteasome subunit alpha type. (277 aa)
ZFP36ZFP36 ring finger protein. (513 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
ZFP36L2ZFP36 ring finger protein like 2. (705 aa)
PARNPoly(A)-specific ribonuclease. (638 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
TNPO1Transportin 1. (898 aa)
ENSFCAP00000041674AAA domain-containing protein; Belongs to the AAA ATPase family. (189 aa)
LOC111556171Uncharacterized protein. (234 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
LOC111556170Proteasome subunit beta type-8. (276 aa)
ENSFCAP00000040149Uncharacterized protein. (79 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (611 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (667 aa)
KXD1KxDL motif containing 1. (201 aa)
ENSFCAP00000036869Proteasome subunit alpha type. (197 aa)
ANP32ALRRcap domain-containing protein. (249 aa)
ELAVL2ELAV-like protein; Belongs to the RRM elav family. (389 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
TOE1Target of EGR1, exonuclease. (510 aa)
EXOSC4Exosome component 4. (245 aa)
PSMF1Proteasome inhibitor subunit 1. (341 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSFCAP00000033387Uncharacterized protein. (491 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (370 aa)
LOC109502223Ubiquitin-like domain-containing protein. (176 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
EXOSC5Exosome component 5. (235 aa)
EXOSC3Exosome component 3. (450 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
ENSFCAP00000026978Uncharacterized protein. (111 aa)
PSMB6Proteasome subunit beta. (239 aa)
ENSFCAP00000026617Ubiquitin-like domain-containing protein. (78 aa)
EXOSC7Exosome component 7. (441 aa)
EXOSC9Exosome component 9. (261 aa)
LOC101083171Proteasome subunit beta. (276 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
EXOSC2Exosome component 2. (293 aa)
TSPYL5TSPY like 5; Belongs to the nucleosome assembly protein (NAP) family. (415 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (332 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
LOC101083848Proteasome subunit beta. (209 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
RPS27ARibosomal protein S27a. (156 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
PSMA6Proteasome subunit alpha type. (251 aa)
ANP32EAcidic nuclear phosphoprotein 32 family member E. (267 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1027 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
ELAVL3ELAV-like protein; Belongs to the RRM elav family. (367 aa)
PSMB11Proteasome subunit beta. (276 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (284 aa)
TSPYL4TSPY like 4; Belongs to the nucleosome assembly protein (NAP) family. (466 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (253 aa)
PSMB7Proteasome subunit beta. (277 aa)
MAPKAPK2MAPK activated protein kinase 2. (409 aa)
PSMB10Proteasome subunit beta. (273 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
M3WFK5_FELCAPABC domain-containing protein. (264 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1604 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
M3W518_FELCAUncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (329 aa)
SETUncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (288 aa)
FUBP3Far upstream element binding protein 3. (572 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
DCP1ADecapping mRNA 1A. (580 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (531 aa)
XPO1Exportin 1. (1071 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
DCP2Decapping mRNA 2. (422 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (355 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (478 aa)
TNPO2Transportin 2. (896 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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