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| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (874 aa) |
| | E2F3 | E2F transcription factor 3. (523 aa) |
| | CA13 | Carbonic anhydrase 13. (534 aa) |
| | ENSFCAP00000061943 | Uncharacterized protein. (120 aa) |
| | ENSFCAP00000061455 | Uncharacterized protein. (157 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (595 aa) |
| | SKP1 | Uncharacterized protein; Belongs to the SKP1 family. (168 aa) |
| | SKP2 | S-phase kinase associated protein 2. (451 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (571 aa) |
| | PSMB3 | Proteasome subunit beta. (268 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (326 aa) |
| | WEE1 | WEE1 G2 checkpoint kinase. (664 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (624 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (772 aa) |
| | ENSFCAP00000055272 | Uncharacterized protein; Belongs to the SKP1 family. (147 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (641 aa) |
| | PSMA3 | Proteasome subunit alpha type. (258 aa) |
| | ENSFCAP00000053469 | PA28_beta domain-containing protein. (192 aa) |
| | TESMIN | Testis expressed metallothionein like protein. (541 aa) |
| | PSMB1 | Proteasome subunit beta. (261 aa) |
| | ENSFCAP00000052091 | Uncharacterized protein. (1125 aa) |
| | PSME3 | Uncharacterized protein. (265 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (312 aa) |
| | PSME2 | Proteasome activator subunit 2. (253 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (637 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (116 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2284 aa) |
| | JAK2 | Tyrosine-protein kinase. (1131 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (338 aa) |
| | TFDP1 | Transcription factor. (423 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (423 aa) |
| | ENSFCAP00000048496 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (62 aa) |
| | LOC101082405 | AAA domain-containing protein. (330 aa) |
| | PSMA4 | Proteasome subunit alpha type. (277 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (264 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | ENSFCAP00000041674 | AAA domain-containing protein; Belongs to the AAA ATPase family. (189 aa) |
| | LOC111556171 | Uncharacterized protein. (234 aa) |
| | SRC | Tyrosine-protein kinase. (678 aa) |
| | LOC111556170 | Proteasome subunit beta type-8. (276 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1150 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (116 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1139 aa) |
| | KXD1 | KxDL motif containing 1. (201 aa) |
| | ENSFCAP00000037196 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (56 aa) |
| | CDC45 | Cell division cycle 45. (567 aa) |
| | ENSFCAP00000036869 | Proteasome subunit alpha type. (197 aa) |
| | CEP170 | Centrosomal protein 170. (1588 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (341 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (418 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa) |
| | LOC109502223 | Ubiquitin-like domain-containing protein. (176 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | ENSFCAP00000030965 | Protein kinase domain-containing protein. (104 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (929 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (583 aa) |
| | DYRK1B | Dual specificity tyrosine phosphorylation regulated kinase 1B. (789 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | FNDC3B | Fibronectin type III domain containing 3B. (1207 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | ENSFCAP00000026978 | Uncharacterized protein. (111 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | ENSFCAP00000026617 | Ubiquitin-like domain-containing protein. (78 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | LOC101083171 | Proteasome subunit beta. (276 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (562 aa) |
| | RB1 | RB transcriptional corepressor 1. (930 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (829 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) |
| | CDC7 | Cell division cycle 7. (574 aa) |
| | LYN | Tyrosine-protein kinase. (526 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (406 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | LOC101083848 | Proteasome subunit beta. (209 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | DBF4 | DBF4 zinc finger. (676 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | FNDC3A | Fibronectin type III domain containing 3A. (1199 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | KIAA2012 | Uncharacterized protein. (1180 aa) |
| | RPS27A | Ribosomal protein S27a. (156 aa) |
| | PSMA6 | Proteasome subunit alpha type. (251 aa) |
| | CDK4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (303 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1068 aa) |
| | ORC2 | Origin recognition complex subunit 2. (602 aa) |
| | PPP2R3B | Protein phosphatase 2 regulatory subunit B''beta. (579 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | GMNN | Geminin DNA replication inhibitor. (210 aa) |
| | PSMD9 | Proteasome 26S subunit, non-ATPase 9. (284 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | LOC101092674 | WRNPLPNID domain-containing protein. (951 aa) |
| | WEE2 | Wee1-like protein kinase. (568 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | MCM5 | Minichromosome maintenance complex component 5; Belongs to the MCM family. (907 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1222 aa) |
| | FNBP4 | Formin binding protein 4. (1020 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | E2F2 | E2F transcription factor 2. (442 aa) |
| | MCM8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (833 aa) |
| | PSMA1 | Proteasome subunit alpha type. (263 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | MYBL2 | MYB proto-oncogene like 2. (702 aa) |
| | UBA52 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa) |
| | E2F4 | E2F transcription factor 4. (406 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | CDC25A | Cell division cycle 25A. (524 aa) |
| | ORC3 | Origin recognition complex subunit 3. (712 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | TM4SF19 | Uncharacterized protein. (209 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (618 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (420 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (949 aa) |
| | OPTN | Optineurin. (874 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (606 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | TFDP2 | Transcription factor. (386 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (851 aa) |
| | POLA1 | DNA polymerase. (1468 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (599 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (355 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (478 aa) |
