STRINGSTRING
LOC111556171 LOC111556171 PSMD6 PSMD6 PSMC2 PSMC2 PSMD8 PSMD8 PSMC4 PSMC4 NFKB2 NFKB2 PSMD5 PSMD5 RPS6KA5 RPS6KA5 PSMB4 PSMB4 PDPK1 PDPK1 PSMD13 PSMD13 NFAT5 NFAT5 HRAS HRAS PSMC5 PSMC5 UBE2M UBE2M PRKCD PRKCD PAK1 PAK1 UBE2N UBE2N EP300 EP300 PSME1 PSME1 IL1B IL1B CREBBP CREBBP NFKBIA NFKBIA CLEC4D CLEC4D NFKB1 NFKB1 PSMD2 PSMD2 SRMS SRMS UBA52 UBA52 TAB2 TAB2 PSMA1 PSMA1 TAB1 TAB1 PSMB10 PSMB10 MAP3K14 MAP3K14 MALT1 MALT1 SYK SYK PSMB7 PSMB7 KRAS KRAS CALM2 CALM2 M3WQU5_FELCA M3WQU5_FELCA PSMD9 PSMD9 PSMB11 PSMB11 PAK2 PAK2 MAP3K7 MAP3K7 PSMD7 PSMD7 PSMA6 PSMA6 RPS27A RPS27A PRKACA PRKACA CD209 CD209 FYN FYN IKBKG IKBKG LOC101083848 LOC101083848 PSMD12 PSMD12 PSMD10 PSMD10 LYN LYN NFATC3 NFATC3 TAB3 TAB3 PSMD11 PSMD11 PSMA2 PSMA2 CUL1 CUL1 PSMA8 PSMA8 PPP3CB PPP3CB LOC101083171 LOC101083171 RELB RELB ENSFCAP00000026617 ENSFCAP00000026617 PSMB6 PSMB6 ENSFCAP00000026978 ENSFCAP00000026978 CALML3 CALML3 LOC101097703 LOC101097703 ENSFCAP00000029012 ENSFCAP00000029012 PTK6 PTK6 CLEC4A CLEC4A CARD9 CARD9 RAF1 RAF1 LOC109502223 LOC109502223 PSMA5 PSMA5 NRAS NRAS PSMF1 PSMF1 CARD11 CARD11 ENSFCAP00000035090 ENSFCAP00000035090 PSMC1 PSMC1 CNRIP1 CNRIP1 ENSFCAP00000036869 ENSFCAP00000036869 PPP3CA PPP3CA CLEC4E CLEC4E KXD1 KXD1 FCER1G FCER1G LOC111556170 LOC111556170 PRKACB PRKACB BTRC BTRC SRC SRC ENSFCAP00000041674 ENSFCAP00000041674 PLCG2 PLCG2 PSMC3 PSMC3 PSMD14 PSMD14 IKBKB IKBKB NFATC2 NFATC2 CLEC6A CLEC6A MAP3K20 MAP3K20 PAK3 PAK3 PSMA4 PSMA4 TRAF6 TRAF6 PSME4 PSME4 RELA RELA LOC101082405 LOC101082405 PSMD4 PSMD4 PSMB5 PSMB5 FBXW11 FBXW11 CALM1 CALM1 BCL10 BCL10 PSMD1 PSMD1 PYCARD PYCARD PSME2 PSME2 PSME3 PSME3 PSMB1 PSMB1 ENSFCAP00000053469 ENSFCAP00000053469 CCDC71L CCDC71L UBE2D1 UBE2D1 PSMA3 PSMA3 NFATC1 NFATC1 WDR92 WDR92 CASP8 CASP8 ENSFCAP00000055272 ENSFCAP00000055272 CALM3 CALM3 TMEM189 TMEM189 UBA3 UBA3 PSMA7 PSMA7 ENSFCAP00000058202 ENSFCAP00000058202 CLEC7A CLEC7A PSMB2 PSMB2 PSMC6 PSMC6 PSMB3 PSMB3 MAP4 MAP4 ENSFCAP00000060347 ENSFCAP00000060347 SKP1 SKP1 CHUK CHUK PSMD3 PSMD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111556171Uncharacterized protein. (234 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (478 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (355 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
NFKB2Nuclear factor kappa B subunit 2. (921 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
NFAT5Nuclear factor of activated T cells 5. (1549 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
EP300E1A binding protein p300. (2425 aa)
PSME1Proteasome activator subunit 1. (249 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa)
CREBBPCREB binding protein. (2444 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
CLEC4DC-type lectin domain family 4 member D. (284 aa)
NFKB1Nuclear factor kappa B subunit 1. (989 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
SRMSTyrosine-protein kinase. (507 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
PSMB10Proteasome subunit beta. (273 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (954 aa)
MALT1MALT1 paracaspase. (848 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
PSMB7Proteasome subunit beta. (277 aa)
KRASUncharacterized protein. (380 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
M3WQU5_FELCAEF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (284 aa)
PSMB11Proteasome subunit beta. (276 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA6Proteasome subunit alpha type. (251 aa)
RPS27ARibosomal protein S27a. (156 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
CD209C-type lectin domain-containing protein. (250 aa)
FYNTyrosine-protein kinase. (589 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (423 aa)
LOC101083848Proteasome subunit beta. (209 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LYNTyrosine-protein kinase. (526 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CUL1Cullin 1; Belongs to the cullin family. (829 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
LOC101083171Proteasome subunit beta. (276 aa)
RELBRELB proto-oncogene, NF-kB subunit. (582 aa)
ENSFCAP00000026617Ubiquitin-like domain-containing protein. (78 aa)
PSMB6Proteasome subunit beta. (239 aa)
ENSFCAP00000026978Uncharacterized protein. (111 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
LOC101097703EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
ENSFCAP00000029012Uncharacterized protein; Belongs to the calmodulin family. (124 aa)
PTK6Tyrosine-protein kinase. (450 aa)
CLEC4AC-type lectin domain family 4 member A. (238 aa)
CARD9Caspase recruitment domain family member 9. (732 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
LOC109502223Ubiquitin-like domain-containing protein. (176 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PSMF1Proteasome inhibitor subunit 1. (341 aa)
CARD11Caspase recruitment domain family member 11. (1163 aa)
ENSFCAP00000035090C-type lectin domain-containing protein. (232 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
CNRIP1Uncharacterized protein. (324 aa)
ENSFCAP00000036869Proteasome subunit alpha type. (197 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CLEC4EC-type lectin domain family 4 member E. (228 aa)
KXD1KxDL motif containing 1. (201 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
LOC111556170Proteasome subunit beta type-8. (276 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
SRCTyrosine-protein kinase. (678 aa)
ENSFCAP00000041674AAA domain-containing protein; Belongs to the AAA ATPase family. (189 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1318 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (760 aa)
NFATC2Nuclear factor of activated T cells 2. (916 aa)
CLEC6AC-type lectin domain containing 6A. (212 aa)
MAP3K20Uncharacterized protein. (800 aa)
PAK3P21 (RAC1) activated kinase 3. (589 aa)
PSMA4Proteasome subunit alpha type. (277 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
PSME4Proteasome activator subunit 4. (1865 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
LOC101082405AAA domain-containing protein. (330 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (423 aa)
PSMB5Proteasome subunit beta. (263 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (192 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PYCARDPYD and CARD domain containing. (195 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSME3Uncharacterized protein. (265 aa)
PSMB1Proteasome subunit beta. (261 aa)
ENSFCAP00000053469PA28_beta domain-containing protein. (192 aa)
CCDC71LCoiled-coil domain containing 71 like. (238 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
PSMA3Proteasome subunit alpha type. (258 aa)
NFATC1Nuclear factor of activated T cells 1. (1085 aa)
WDR92WD repeat domain 92. (363 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (479 aa)
ENSFCAP00000055272Uncharacterized protein; Belongs to the SKP1 family. (147 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (276 aa)
TMEM189Transmembrane protein 189. (296 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (472 aa)
PSMA7Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (358 aa)
ENSFCAP00000058202Uncharacterized protein. (99 aa)
CLEC7AC-type lectin domain containing 7A. (250 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa)
PSMB3Proteasome subunit beta. (268 aa)
MAP4Microtubule-associated protein. (1134 aa)
ENSFCAP00000060347Uncharacterized protein; Belongs to the calmodulin family. (146 aa)
SKP1Uncharacterized protein; Belongs to the SKP1 family. (168 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (774 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (595 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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