STRINGSTRING
RACK1 RACK1 ENSFCAP00000028212 ENSFCAP00000028212 NSMAF NSMAF TNFRSF1A TNFRSF1A SMPD2 SMPD2 ENSFCAP00000030321 ENSFCAP00000030321 SMPD3 SMPD3 TNF TNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RACK1WD_REPEATS_REGION domain-containing protein. (424 aa)
ENSFCAP00000028212Uncharacterized protein. (83 aa)
NSMAFNeutral sphingomyelinase activation associated factor. (920 aa)
TNFRSF1ATNF receptor superfamily member 1A. (444 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (424 aa)
ENSFCAP00000030321Uncharacterized protein. (79 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (674 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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