20 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAC2	Rac family small GTPase 2. (234 aa)
	NCF1	Neutrophil cytosolic factor 1. (390 aa)
	NOXO1	NADPH oxidase organizer 1. (336 aa)
	PRKCZ	Protein kinase C zeta. (649 aa)
	RAC3	Rac family small GTPase 3. (205 aa)
	NOXA1	Uncharacterized protein. (512 aa)
	PIK3R4	Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
	NCF2	Neutrophil cytosolic factor 2. (526 aa)
	NCF4	Neutrophil cytosolic factor 4. (339 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (163 aa)
	XKRX	XK-related protein. (449 aa)
	NOX1	NADPH oxidase 1. (564 aa)
	CYBA	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
	NOX3	NADPH oxidase 3. (567 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	S100A9	Protein S100; Belongs to the S-100 family. (135 aa)
	S100A8	Protein S100; Belongs to the S-100 family. (124 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYBA	NCF1	ENSFCAP00000006185	ENSFCAP00000059825	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Neutrophil cytosolic factor 1.	0.999
CYBA	NCF2	ENSFCAP00000006185	ENSFCAP00000020056	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Neutrophil cytosolic factor 2.	0.999
CYBA	NCF4	ENSFCAP00000006185	ENSFCAP00000015962	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Neutrophil cytosolic factor 4.	0.982
CYBA	NOX1	ENSFCAP00000006185	ENSFCAP00000006494	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	NADPH oxidase 1.	0.999
CYBA	NOX3	ENSFCAP00000006185	ENSFCAP00000005731	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	NADPH oxidase 3.	0.994
CYBA	NOXA1	ENSFCAP00000006185	ENSFCAP00000045965	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Uncharacterized protein.	0.963
CYBA	NOXO1	ENSFCAP00000006185	ENSFCAP00000058076	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	NADPH oxidase organizer 1.	0.992
CYBA	PRKCD	ENSFCAP00000006185	ENSFCAP00000003598	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.904
CYBA	RAC2	ENSFCAP00000006185	ENSFCAP00000056432	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Rac family small GTPase 2.	0.974
CYBA	RAC3	ENSFCAP00000006185	ENSFCAP00000052251	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Rac family small GTPase 3.	0.830
CYBA	S100A9	ENSFCAP00000006185	ENSFCAP00000002948	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	Protein S100; Belongs to the S-100 family.	0.436
CYBA	XKRX	ENSFCAP00000006185	ENSFCAP00000006495	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	XK-related protein.	0.688
NCF1	CYBA	ENSFCAP00000059825	ENSFCAP00000006185	Neutrophil cytosolic factor 1.	Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.	0.999
NCF1	NCF2	ENSFCAP00000059825	ENSFCAP00000020056	Neutrophil cytosolic factor 1.	Neutrophil cytosolic factor 2.	0.999
NCF1	NCF4	ENSFCAP00000059825	ENSFCAP00000015962	Neutrophil cytosolic factor 1.	Neutrophil cytosolic factor 4.	0.999
NCF1	NOX1	ENSFCAP00000059825	ENSFCAP00000006494	Neutrophil cytosolic factor 1.	NADPH oxidase 1.	0.996
NCF1	NOX3	ENSFCAP00000059825	ENSFCAP00000005731	Neutrophil cytosolic factor 1.	NADPH oxidase 3.	0.968
NCF1	NOXA1	ENSFCAP00000059825	ENSFCAP00000045965	Neutrophil cytosolic factor 1.	Uncharacterized protein.	0.989
NCF1	NOXO1	ENSFCAP00000059825	ENSFCAP00000058076	Neutrophil cytosolic factor 1.	NADPH oxidase organizer 1.	0.803
NCF1	PRKCA	ENSFCAP00000059825	ENSFCAP00000011143	Neutrophil cytosolic factor 1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.961