STRINGSTRING
UBE2L3 UBE2L3 TRAF2 TRAF2 TTC6 TTC6 RIPK3 RIPK3 STUB1 STUB1 BIRC7 BIRC7 UBA52 UBA52 XIAP XIAP BIRC3 BIRC3 RIPK1 RIPK1 RPS27A RPS27A ENSFCAP00000026617 ENSFCAP00000026617 PELI1 PELI1 OGT OGT NAIP NAIP LOC109502223 LOC109502223 KXD1 KXD1 PRKN PRKN CFLAR CFLAR FADD FADD TRADD TRADD CASP8 CASP8 PDCD6IP PDCD6IP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBE2L3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (247 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
TTC6TPR_REGION domain-containing protein. (1880 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (509 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
BIRC7Baculoviral IAP repeat containing 7. (287 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
XIAPX-linked inhibitor of apoptosis. (454 aa)
BIRC3Baculoviral IAP repeat containing 3. (624 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
RPS27ARibosomal protein S27a. (156 aa)
ENSFCAP00000026617Ubiquitin-like domain-containing protein. (78 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
NAIPNACHT domain-containing protein. (1436 aa)
LOC109502223Ubiquitin-like domain-containing protein. (176 aa)
KXD1KxDL motif containing 1. (201 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (508 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa)
TRADDTNFRSF1A associated via death domain. (311 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (479 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (893 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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