19 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	M3X4N1_FELCA	Uncharacterized protein. (70 aa)
	PRELID1	PRELI domain containing 1. (219 aa)
	AIFM3	Apoptosis inducing factor mitochondria associated 3. (605 aa)
	ZNF529	Zinc finger protein 529. (531 aa)
	BNIP3L	BCL2 interacting protein 3 like. (219 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
	STEAP3	STEAP3 metalloreductase. (522 aa)
	ZNF420	Zinc finger protein 420. (689 aa)
	ENSFCAP00000034863	PRELI/MSF1 domain-containing protein. (164 aa)
	TRIAP1	TP53 regulated inhibitor of apoptosis 1. (76 aa)
	ZNF345	Zinc finger protein 345. (492 aa)
	ZNF573	Zinc finger protein 573. (612 aa)
	PRELID3A	PRELI domain containing 3A. (182 aa)
	LOC101082283	Uncharacterized protein. (643 aa)
	ENSFCAP00000045322	KRAB domain-containing protein. (85 aa)
	LOC111556200	Uncharacterized protein. (696 aa)
	AIFM2	Apoptosis inducing factor mitochondria associated 2. (491 aa)
	PRELID3B	PRELI domain containing 3B. (327 aa)
	BNIP3	BCL2 interacting protein 3. (187 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	ENSFCAP00000045322	ENSFCAP00000025928	ENSFCAP00000045322	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	KRAB domain-containing protein.	0.445
ATM	LOC101082283	ENSFCAP00000025928	ENSFCAP00000045211	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.594
ATM	LOC111556200	ENSFCAP00000025928	ENSFCAP00000048215	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.445
ATM	ZNF345	ENSFCAP00000025928	ENSFCAP00000036265	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Zinc finger protein 345.	0.445
ATM	ZNF420	ENSFCAP00000025928	ENSFCAP00000033927	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Zinc finger protein 420.	0.445
ATM	ZNF573	ENSFCAP00000025928	ENSFCAP00000040326	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Zinc finger protein 573.	0.445
BNIP3	BNIP3L	ENSFCAP00000061759	ENSFCAP00000025274	BCL2 interacting protein 3.	BCL2 interacting protein 3 like.	0.761
BNIP3	STEAP3	ENSFCAP00000061759	ENSFCAP00000028893	BCL2 interacting protein 3.	STEAP3 metalloreductase.	0.577
BNIP3L	BNIP3	ENSFCAP00000025274	ENSFCAP00000061759	BCL2 interacting protein 3 like.	BCL2 interacting protein 3.	0.761
BNIP3L	STEAP3	ENSFCAP00000025274	ENSFCAP00000028893	BCL2 interacting protein 3 like.	STEAP3 metalloreductase.	0.933
ENSFCAP00000034863	M3X4N1_FELCA	ENSFCAP00000034863	ENSFCAP00000021581	PRELI/MSF1 domain-containing protein.	Uncharacterized protein.	0.770
ENSFCAP00000034863	PRELID1	ENSFCAP00000034863	ENSFCAP00000001422	PRELI/MSF1 domain-containing protein.	PRELI domain containing 1.	0.743
ENSFCAP00000034863	TRIAP1	ENSFCAP00000034863	ENSFCAP00000035357	PRELI/MSF1 domain-containing protein.	TP53 regulated inhibitor of apoptosis 1.	0.770
ENSFCAP00000045322	ATM	ENSFCAP00000045322	ENSFCAP00000025928	KRAB domain-containing protein.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.445
LOC101082283	ATM	ENSFCAP00000045211	ENSFCAP00000025928	Uncharacterized protein.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.594
LOC111556200	ATM	ENSFCAP00000048215	ENSFCAP00000025928	Uncharacterized protein.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.445
M3X4N1_FELCA	ENSFCAP00000034863	ENSFCAP00000021581	ENSFCAP00000034863	Uncharacterized protein.	PRELI/MSF1 domain-containing protein.	0.770
M3X4N1_FELCA	PRELID1	ENSFCAP00000021581	ENSFCAP00000001422	Uncharacterized protein.	PRELI domain containing 1.	0.979
M3X4N1_FELCA	PRELID3A	ENSFCAP00000021581	ENSFCAP00000040417	Uncharacterized protein.	PRELI domain containing 3A.	0.770
M3X4N1_FELCA	PRELID3B	ENSFCAP00000021581	ENSFCAP00000059237	Uncharacterized protein.	PRELI domain containing 3B.	0.770