18 items (Felis catus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	PPP1R13L	Protein phosphatase 1 regulatory subunit 13 like. (867 aa)
	POU4F2	POU domain protein. (408 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ZNF385A	Zinc finger protein 385A. (386 aa)
	TP73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (749 aa)
	BANP	BTG3 associated nuclear protein. (528 aa)
	POU4F3	POU domain protein. (338 aa)
	PHF20	PHD finger protein 20. (1013 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	PPP1R13B	Protein phosphatase 1 regulatory subunit 13B. (1092 aa)
	ZNF385B	Zinc finger protein 385B. (489 aa)
	C17orf113	Chromosome 17 open reading frame 113. (675 aa)
	POU4F1	POU domain protein. (421 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
	TP53BP2	Tumor protein p53 binding protein 2. (1211 aa)
	ZNF385C	Zinc finger protein 385C. (542 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	AKT3	ENSFCAP00000004586	ENSFCAP00000003410	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT1	PHF20	ENSFCAP00000004586	ENSFCAP00000022981	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	PHD finger protein 20.	0.469
AKT1	TP53	ENSFCAP00000004586	ENSFCAP00000045749	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.455
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	AKT3	ENSFCAP00000059662	ENSFCAP00000003410	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.918
AKT2	PHF20	ENSFCAP00000059662	ENSFCAP00000022981	Non-specific serine/threonine protein kinase.	PHD finger protein 20.	0.469
AKT2	TP53	ENSFCAP00000059662	ENSFCAP00000045749	Non-specific serine/threonine protein kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.455
AKT3	AKT1	ENSFCAP00000003410	ENSFCAP00000004586	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT3	AKT2	ENSFCAP00000003410	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.918
AKT3	PHF20	ENSFCAP00000003410	ENSFCAP00000022981	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	PHD finger protein 20.	0.469
AKT3	TP53	ENSFCAP00000003410	ENSFCAP00000045749	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.455
BANP	TP53	ENSFCAP00000011173	ENSFCAP00000045749	BTG3 associated nuclear protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.799
BANP	TP63	ENSFCAP00000011173	ENSFCAP00000027896	BTG3 associated nuclear protein.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.512
BANP	TP73	ENSFCAP00000011173	ENSFCAP00000010792	BTG3 associated nuclear protein.	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	0.512
C17orf113	TP53	ENSFCAP00000042402	ENSFCAP00000045749	Chromosome 17 open reading frame 113.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.429
PHF20	AKT1	ENSFCAP00000022981	ENSFCAP00000004586	PHD finger protein 20.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.469
PHF20	AKT2	ENSFCAP00000022981	ENSFCAP00000059662	PHD finger protein 20.	Non-specific serine/threonine protein kinase.	0.469
PHF20	AKT3	ENSFCAP00000022981	ENSFCAP00000003410	PHD finger protein 20.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.469
PHF20	TP53	ENSFCAP00000022981	ENSFCAP00000045749	PHD finger protein 20.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.724