STRINGSTRING
OTUD3 OTUD3 LOC101083848 LOC101083848 PSMD12 PSMD12 RRAGD RRAGD PSMD10 PSMD10 RRAGA RRAGA TRIM27 TRIM27 LAMTOR5 LAMTOR5 SUZ12 SUZ12 LY6G5B LY6G5B ATN1 ATN1 PSMD11 PSMD11 PSMA2 PSMA2 USP13 USP13 M3XC26_FELCA M3XC26_FELCA CBX7 CBX7 PSMA8 PSMA8 OTUD4 OTUD4 LOC101083171 LOC101083171 SLC38A9 SLC38A9 ENSFCAP00000026617 ENSFCAP00000026617 LAMTOR3 LAMTOR3 MLST8 MLST8 PSMB6 PSMB6 ENSFCAP00000026978 ENSFCAP00000026978 BMI1 BMI1 EGR1 EGR1 TNKS TNKS LOC109502223 LOC109502223 HDAC1 HDAC1 MECOM MECOM PSMA5 PSMA5 PSMF1 PSMF1 USP7 USP7 HDAC2 HDAC2 CHD3 CHD3 TXNDC11 TXNDC11 SALL4 SALL4 PSMC1 PSMC1 CEP170 CEP170 ENSFCAP00000036869 ENSFCAP00000036869 KXD1 KXD1 ENSFCAP00000039879 ENSFCAP00000039879 LOC111556170 LOC111556170 LAMTOR4 LAMTOR4 LOC111556171 LOC111556171 SCML1 SCML1 ENSFCAP00000041674 ENSFCAP00000041674 RPTOR RPTOR EZH1 EZH1 CBX2 CBX2 PSMC3 PSMC3 PSMD14 PSMD14 SALL2 SALL2 RNF2 RNF2 SNAI3 SNAI3 RERE RERE LOC101086561 LOC101086561 TNKS2 TNKS2 CSNK2A1 CSNK2A1 PSMA4 PSMA4 PSME4 PSME4 LOC101082405 LOC101082405 PSMD4 PSMD4 PSMB5 PSMB5 CBX4 CBX4 CBX8 CBX8 PHC3 PHC3 PSMD1 PSMD1 SCMH1 SCMH1 MTA1 MTA1 PSME2 PSME2 PSME3 PSME3 ENSFCAP00000052659 ENSFCAP00000052659 KIAA1671 KIAA1671 PSMB1 PSMB1 GATAD2B GATAD2B ENSFCAP00000053469 ENSFCAP00000053469 NPTXR NPTXR LAMTOR2 LAMTOR2 PSMA3 PSMA3 CBX6 CBX6 ENSFCAP00000055099 ENSFCAP00000055099 GATAD2A GATAD2A PSMA7 PSMA7 SCML2 SCML2 PSMB2 PSMB2 PSMC6 PSMC6 PSMB3 PSMB3 AKT2 AKT2 MKRN3 MKRN3 PSMD3 PSMD3 ENSFCAP00000061684 ENSFCAP00000061684 MTOR MTOR RHEBL1 RHEBL1 PSMD6 PSMD6 PSMC2 PSMC2 MBD3 MBD3 PSMD8 PSMD8 PSMC4 PSMC4 PSMD5 PSMD5 EED EED PSMB4 PSMB4 PSMD13 PSMD13 WWP2 WWP2 TRIM7 TRIM7 PML PML PSMC5 PSMC5 PHC2 PHC2 AKT3 AKT3 LOC111556167 LOC111556167 FRK FRK NPTX2 NPTX2 AKT1 AKT1 LAMTOR1 LAMTOR1 PSME1 PSME1 CHD5 CHD5 CHD4 CHD4 CSNK2B CSNK2B PSMD2 PSMD2 AIRE AIRE MKRN2 MKRN2 NEDD4 NEDD4 STUB1 STUB1 EZH2 EZH2 MTA3 MTA3 MTA2 MTA2 PREX2 PREX2 RRAGC RRAGC UBA52 UBA52 SNAI1 SNAI1 PSMA1 PSMA1 MAF1 MAF1 XIAP XIAP PSMB10 PSMB10 RHEB RHEB CRYGN CRYGN CRYBB3 CRYBB3 RRAGB RRAGB PSMB7 PSMB7 RNF146 RNF146 PHC1 PHC1 SNAI2 SNAI2 PTEN PTEN GUF1 GUF1 PSMD9 PSMD9 PSMB11 PSMB11 RBBP4 RBBP4 RNF141 RNF141 PSMD7 PSMD7 PSMA6 PSMA6 MKRN1 MKRN1 RPS27A RPS27A CSNK2A2 CSNK2A2 RBBP7 RBBP7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OTUD3OTU deubiquitinase 3. (398 aa)
LOC101083848Proteasome subunit beta. (209 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
RRAGDRas related GTP binding D. (396 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
RRAGARas related GTP binding A. (313 aa)
TRIM27Tripartite motif containing 27. (513 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (738 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (216 aa)
ATN1Atrophin 1. (1193 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
M3XC26_FELCAUncharacterized protein. (124 aa)
CBX7Chromobox 7. (250 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
OTUD4OTU deubiquitinase 4. (1107 aa)
LOC101083171Proteasome subunit beta. (276 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
ENSFCAP00000026617Ubiquitin-like domain-containing protein. (78 aa)
LAMTOR3Uncharacterized protein. (124 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
PSMB6Proteasome subunit beta. (239 aa)
ENSFCAP00000026978Uncharacterized protein. (111 aa)
BMI1Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...] (326 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
LOC109502223Ubiquitin-like domain-containing protein. (176 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa)
MECOMMDS1 and EVI1 complex locus. (1239 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMF1Proteasome inhibitor subunit 1. (341 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1107 aa)
HDAC2Histone deacetylase 2. (602 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2057 aa)
TXNDC11Thioredoxin domain containing 11. (961 aa)
SALL4Spalt like transcription factor 4. (1058 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
CEP170Centrosomal protein 170. (1588 aa)
ENSFCAP00000036869Proteasome subunit alpha type. (197 aa)
KXD1KxDL motif containing 1. (201 aa)
ENSFCAP00000039879Uncharacterized protein. (148 aa)
LOC111556170Proteasome subunit beta type-8. (276 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (146 aa)
LOC111556171Uncharacterized protein. (234 aa)
SCML1SAM domain-containing protein. (372 aa)
ENSFCAP00000041674AAA domain-containing protein; Belongs to the AAA ATPase family. (189 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (829 aa)
CBX2Chromobox 2. (529 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
SALL2Spalt like transcription factor 2. (1101 aa)
RNF2Ring finger protein 2. (336 aa)
SNAI3Snail family transcriptional repressor 3. (296 aa)
REREArginine-glutamic acid dipeptide repeats. (1547 aa)
LOC101086561E3 ubiquitin-protein ligase RING1. (406 aa)
TNKS2Poly [ADP-ribose] polymerase. (1344 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
PSMA4Proteasome subunit alpha type. (277 aa)
PSME4Proteasome activator subunit 4. (1865 aa)
LOC101082405AAA domain-containing protein. (330 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (423 aa)
PSMB5Proteasome subunit beta. (263 aa)
CBX4Chromobox 4. (686 aa)
CBX8Chromobox 8. (573 aa)
PHC3Polyhomeotic homolog 3. (1011 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
SCMH1Scm polycomb group protein homolog 1. (844 aa)
MTA1Metastasis associated 1. (719 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSME3Uncharacterized protein. (265 aa)
ENSFCAP00000052659Uncharacterized protein. (184 aa)
KIAA1671KIAA1671. (1838 aa)
PSMB1Proteasome subunit beta. (261 aa)
GATAD2BGATA zinc finger domain containing 2B. (598 aa)
ENSFCAP00000053469PA28_beta domain-containing protein. (192 aa)
NPTXRNeuronal pentraxin receptor. (508 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (149 aa)
PSMA3Proteasome subunit alpha type. (258 aa)
CBX6Chromobox 6. (415 aa)
ENSFCAP00000055099Uncharacterized protein. (115 aa)
GATAD2AGATA zinc finger domain containing 2A. (756 aa)
PSMA7Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (358 aa)
SCML2Scm polycomb group protein like 2. (748 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa)
PSMB3Proteasome subunit beta. (268 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
MKRN3Makorin ring finger protein 3. (433 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (595 aa)
ENSFCAP00000061684Uncharacterized protein. (410 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa)
RHEBL1RHEB like 1. (183 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (478 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
MBD3Methyl-CpG binding domain protein 3. (301 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (355 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
EEDEmbryonic ectoderm development. (441 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
WWP2E3 ubiquitin-protein ligase. (875 aa)
TRIM7Tripartite motif containing 7. (506 aa)
PMLPromyelocytic leukemia. (876 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PHC2Polyhomeotic homolog 2. (849 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC111556167RING-type domain-containing protein. (406 aa)
FRKTyrosine-protein kinase. (514 aa)
NPTX2Neuronal pentraxin 2. (431 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
PSME1Proteasome activator subunit 1. (249 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1947 aa)
CHD4Uncharacterized protein. (1912 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
AIREAutoimmune regulator. (549 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1323 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (460 aa)
MTA3Metastasis associated 1 family member 3. (594 aa)
MTA2Metastasis associated 1 family member 2. (630 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1605 aa)
RRAGCRas related GTP binding C. (398 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
MAF1Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (288 aa)
XIAPX-linked inhibitor of apoptosis. (454 aa)
PSMB10Proteasome subunit beta. (273 aa)
RHEBRas homolog, mTORC1 binding. (187 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (183 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
RRAGBRas related GTP binding B. (374 aa)
PSMB7Proteasome subunit beta. (277 aa)
RNF146Ring finger protein 146. (356 aa)
PHC1Polyhomeotic homolog 1. (1009 aa)
SNAI2Uncharacterized protein. (268 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (669 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (284 aa)
PSMB11Proteasome subunit beta. (276 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
RNF141Ring finger protein 141. (230 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA6Proteasome subunit alpha type. (251 aa)
MKRN1Makorin ring finger protein 1. (482 aa)
RPS27ARibosomal protein S27a. (156 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (469 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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