STRINGSTRING
GSN GSN DBNL DBNL HMGB4 HMGB4 HMGB1 HMGB1 CASP7 CASP7 H1-8 H1-8 LMNTD1 LMNTD1 LMNB2 LMNB2 MAP2 MAP2 LMNTD2 LMNTD2 KPNA1 KPNA1 STK24 STK24 VIM VIM LOC101084636 LOC101084636 CDH1 CDH1 DSG2 DSG2 DFFA DFFA DSG1 DSG1 SH3GLB2 SH3GLB2 DUS4L DUS4L MAPT MAPT APC2 APC2 PLEC PLEC PRKCQ PRKCQ TJP2 TJP2 SATB1 SATB1 APC APC ENSFCAP00000037707 ENSFCAP00000037707 ROCK1 ROCK1 PTK2 PTK2 CASP3 CASP3 GAS2 GAS2 SPTAN1 SPTAN1 ENSFCAP00000028410 ENSFCAP00000028410 HMGB3 HMGB3 CLSPN CLSPN TJP1 TJP1 ADD1 ADD1 CASP6 CASP6 SH3GLB1 SH3GLB1 H1-0 H1-0 DSG3 DSG3 M3X2M0_FELCA M3X2M0_FELCA STK26 STK26 KPNB1 KPNB1 FNTA FNTA LMNA LMNA DFFB DFFB BMX BMX DSP DSP OCLN OCLN TJP3 TJP3 H1-3 H1-3 TMEM198 TMEM198 H1-5 H1-5 H1-6 H1-6 H1-1 H1-1 SCIN SCIN PKP1 PKP1 HMGB2 HMGB2 BCAP31 BCAP31 PRKCD PRKCD H1-2 H1-2 CTNNB1 CTNNB1 CAPG CAPG LMNB1 LMNB1 STK25 STK25 ACIN1 ACIN1 HP1BP3 HP1BP3 CASP8 CASP8 EPPK1 EPPK1 H1-4 H1-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSNGelsolin. (815 aa)
DBNLDrebrin like. (522 aa)
HMGB4High mobility group box 4. (193 aa)
HMGB1Uncharacterized protein. (233 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (409 aa)
H1-8H1 histone family member O oocyte specific. (343 aa)
LMNTD1Lamin tail domain containing 1. (497 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (718 aa)
MAP2Microtubule-associated protein. (1895 aa)
LMNTD2Lamin tail domain containing 2. (674 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (564 aa)
STK24Serine/threonine kinase 24. (470 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
LOC101084636DUF4203 domain-containing protein. (350 aa)
CDH1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (881 aa)
DSG2Desmoglein 2. (1330 aa)
DFFADNA fragmentation factor subunit alpha. (370 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1074 aa)
SH3GLB2SH3 domain containing GRB2 like, endophilin B2. (480 aa)
DUS4LUncharacterized protein. (482 aa)
MAPTMicrotubule-associated protein. (778 aa)
APC2APC regulator of WNT signaling pathway 2. (2289 aa)
PLECPlectin. (4686 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (715 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1180 aa)
SATB1DNA-binding protein SATB. (792 aa)
APCAPC regulator of WNT signaling pathway. (2874 aa)
ENSFCAP00000037707Uncharacterized protein. (182 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1112 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa)
GAS2Growth arrest specific 2. (314 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2725 aa)
ENSFCAP00000028410Uncharacterized protein. (195 aa)
HMGB3Uncharacterized protein. (271 aa)
CLSPNClaspin. (1327 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (2008 aa)
ADD1Adducin 1. (761 aa)
CASP6Caspase 6; Belongs to the phospholipase A2 family. (431 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (401 aa)
H1-0H1 histone family member 0. (231 aa)
DSG3Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (985 aa)
M3X2M0_FELCAUncharacterized protein. (175 aa)
STK26Serine/threonine kinase 26. (416 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
FNTAFarnesyltransferase, CAAX box, alpha. (452 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
DFFBDNA fragmentation factor subunit beta. (647 aa)
BMXTyrosine-protein kinase. (630 aa)
DSPDesmoplakin. (2884 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (910 aa)
H1-3Histone cluster 1 H1 family member d. (222 aa)
TMEM198Transmembrane protein 198. (360 aa)
H1-5Histone cluster 1 H1 family member b. (226 aa)
H1-6Histone cluster 1 H1 family member t. (211 aa)
H1-1Histone cluster 1 H1 family member a. (214 aa)
SCINScinderin. (715 aa)
PKP1Plakophilin 1. (727 aa)
HMGB2High mobility group box 2. (210 aa)
BCAP31B cell receptor associated protein 31. (370 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
H1-2Histone cluster 1 H1 family member c. (331 aa)
CTNNB1Catenin beta 1. (783 aa)
CAPGCapping actin protein, gelsolin like. (388 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
STK25Serine/threonine kinase 25. (426 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1339 aa)
HP1BP3Heterochromatin protein 1 binding protein 3. (553 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (479 aa)
EPPK1Epiplakin 1. (3436 aa)
H1-4Histone cluster 1 H1 family member e. (218 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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