STRINGSTRING
TEX264 TEX264 ANXA5 ANXA5 ITIH4 ITIH4 TF TF CD63 CD63 ENSFCAP00000060347 ENSFCAP00000060347 A2M A2M LOC101093854 LOC101093854 EGF EGF SERPING1 SERPING1 FAM49A FAM49A PHACTR1 PHACTR1 ANXA3 ANXA3 PLEK PLEK ENSFCAP00000059017 ENSFCAP00000059017 APOH APOH AHSG AHSG SERPINA1 SERPINA1 PSAP PSAP LOC105261327 LOC105261327 SPP2 SPP2 LOC101094344 LOC101094344 ANXA6 ANXA6 TAGLN2 TAGLN2 LOC101096210 LOC101096210 CHID1 CHID1 ANXA11 ANXA11 CALM3 CALM3 SELP SELP FGG FGG VTI1B VTI1B QSOX1 QSOX1 FETUB FETUB PROS1 PROS1 F8 F8 LOC101080976 LOC101080976 ACTN1 ACTN1 PLEK2 PLEK2 PECAM1 PECAM1 PHACTR4 PHACTR4 A1BG A1BG RARRES2 RARRES2 OLA1-2 OLA1-2 TMSB10 TMSB10 LOC109499896 LOC109499896 CALM1 CALM1 VEGFA VEGFA LOC101087010 LOC101087010 ACTN2 ACTN2 A2ML1 A2ML1 TLNRD1 TLNRD1 ENSFCAP00000048834 ENSFCAP00000048834 CSMD3 CSMD3 HABP4 HABP4 ENSFCAP00000047404 ENSFCAP00000047404 GTPBP1 GTPBP1 LOC101081475 LOC101081475 PCDH7 PCDH7 ENSFCAP00000046486 ENSFCAP00000046486 TENM4 TENM4 LOC101094096 LOC101094096 ENSFCAP00000044600 ENSFCAP00000044600 ENSFCAP00000044477 ENSFCAP00000044477 LOC109494688 LOC109494688 CDC37L1 CDC37L1 SRL SRL IGF1 IGF1 FAM49B FAM49B CYB5R1 CYB5R1 PHACTR3 PHACTR3 ENSFCAP00000039787 ENSFCAP00000039787 FLNA FLNA CD9 CD9 LHFPL6 LHFPL6 TUBA4A TUBA4A TSPAN18 TSPAN18 SYTL5 SYTL5 SOD1 SOD1 LRRC55 LRRC55 IGF2 IGF2 PHACTR2 PHACTR2 HGF HGF ENSFCAP00000033495 ENSFCAP00000033495 ITGB3 ITGB3 MANF MANF CPAMD8 CPAMD8 CDCA7L CDCA7L TGFB2 TGFB2 OLA1 OLA1 ISLR2 ISLR2 DSTN DSTN URB2 URB2 APOOL APOOL CD36 CD36 TIMP3 TIMP3 ENSFCAP00000029012 ENSFCAP00000029012 SRGN SRGN LOC101097703 LOC101097703 TMX3 TMX3 CSMD1 CSMD1 TAGLN3 TAGLN3 CALML3 CALML3 F13A1 F13A1 ACTN4 ACTN4 CTSW CTSW TENM2 TENM2 NDN NDN ENDOD1 ENDOD1 NHLRC2 NHLRC2 RAB27B RAB27B VCL VCL CD109 CD109 PDGFA PDGFA PLG PLG LYRM7 LYRM7 ISLR ISLR STX4 STX4 TENM3 TENM3 BTBD19 BTBD19 SFRP4 SFRP4 FAM3C FAM3C MAGED2 MAGED2 PCYOX1 PCYOX1 ECM1 ECM1 M3WQU5_FELCA M3WQU5_FELCA STXBP3 STXBP3 CALM2 CALM2 APOA1 APOA1 ITIH3 ITIH3 PDGFB PDGFB CLU CLU TGFB3 TGFB3 ALDOA ALDOA GZMK GZMK HRG HRG TMEM211 TMEM211 FRZB FRZB CFL1 CFL1 ANXA4 ANXA4 FGB FGB MMRN1 MMRN1 TLN1 TLN1 SCG3 SCG3 LHFPL1 LHFPL1 QSOX2 QSOX2 PRKCA PRKCA THBS1 THBS1 IGSF3 IGSF3 WDR1 WDR1 PRKCB PRKCB BTBD9 BTBD9 SCCPDH SCCPDH ANXA13 ANXA13 SERPINA3 SERPINA3 SERPINA4 SERPINA4 GTPBP2 GTPBP2 ANXA9 ANXA9 APLP2 APLP2 CLUL1 CLUL1 FN1 FN1 ABCC4 ABCC4 CDNF CDNF CFL2 CFL2 TENM1 TENM1 ANXA7 ANXA7 TIMP1 TIMP1 F5 F5 VEGFC VEGFC SYTL3 SYTL3 LY6G6F LY6G6F CFD CFD TLN2 TLN2 GAS6 GAS6 ORM2 ORM2 LRRC38 LRRC38 SERBP1 SERBP1 CD37 CD37 APP APP PRKCG PRKCG STXBP2 STXBP2 BRPF3 BRPF3 CSMD2 CSMD2 ITGA2B ITGA2B EXOG EXOG FGA FGA SYTL4 SYTL4 PCYOX1L PCYOX1L LRRIQ4 LRRIQ4 LAMP2 LAMP2 ANXA10 ANXA10 CLPB CLPB TGFB1 TGFB1 SERPINE1 SERPINE1 ENDOG ENDOG FERMT3 FERMT3 VEGFB VEGFB SPARC SPARC SERPINF2 SERPINF2 APLP1 APLP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TEX264Testis expressed 264, ER-phagy receptor. (313 aa)
ANXA5Annexin. (329 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (893 aa)
TFTransferrin; Belongs to the transferrin family. (706 aa)
CD63CD63 antigen; Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal tr [...] (249 aa)
ENSFCAP00000060347Uncharacterized protein; Belongs to the calmodulin family. (146 aa)
A2MAlpha-2-macroglobulin. (1511 aa)
LOC101093854C-X-C motif chemokine. (96 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1213 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (512 aa)
FAM49AFamily with sequence similarity 49 member A. (405 aa)
PHACTR1Phosphatase and actin regulator. (801 aa)
ANXA3Annexin. (457 aa)
PLEKPleckstrin. (365 aa)
ENSFCAP00000059017Uncharacterized protein. (73 aa)
APOHApolipoprotein H. (382 aa)
AHSGAlpha 2-HS glycoprotein. (371 aa)
SERPINA1SERPIN domain-containing protein; Belongs to the serpin family. (439 aa)
PSAPProsaposin. (680 aa)
LOC105261327Left-right determination factor. (367 aa)
SPP2Secreted phosphoprotein 2. (243 aa)
LOC101094344C-X-C motif chemokine. (113 aa)
ANXA6Annexin. (723 aa)
TAGLN2Transgelin; Belongs to the calponin family. (218 aa)
LOC101096210MAGE domain-containing protein. (699 aa)
CHID1Chitinase domain containing 1; Belongs to the glycosyl hydrolase 18 family. (509 aa)
ANXA11Annexin. (598 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (276 aa)
SELPSelectin P. (901 aa)
FGGFibrinogen gamma chain. (479 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (247 aa)
QSOX1Sulfhydryl oxidase. (858 aa)
FETUBFetuin B. (419 aa)
PROS1Protein S. (691 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2337 aa)
LOC101080976Uncharacterized protein. (1453 aa)
ACTN1Actinin alpha 1. (927 aa)
PLEK2Pleckstrin 2. (403 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (764 aa)
PHACTR4Phosphatase and actin regulator. (752 aa)
A1BGAlpha-1-B glycoprotein. (542 aa)
RARRES2Retinoic acid receptor responder 2. (451 aa)
OLA1-2Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (429 aa)
TMSB10Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
LOC109499896Uncharacterized protein. (147 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (192 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (450 aa)
LOC101087010Annexin. (395 aa)
ACTN2Actinin alpha 2. (910 aa)
A2ML1Alpha-2-macroglobulin like 1. (1446 aa)
TLNRD1Talin rod domain containing 1. (363 aa)
ENSFCAP00000048834Uncharacterized protein. (139 aa)
CSMD3CUB and Sushi multiple domains 3. (3707 aa)
HABP4Hyaluronan binding protein 4. (416 aa)
ENSFCAP00000047404Uncharacterized protein. (56 aa)
GTPBP1GTP binding protein 1. (674 aa)
LOC101081475Uncharacterized protein. (1406 aa)
PCDH7Protocadherin 7. (1254 aa)
ENSFCAP00000046486Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
TENM4Teneurin transmembrane protein 4. (2823 aa)
LOC101094096C-X-C motif chemokine. (104 aa)
ENSFCAP00000044600Uncharacterized protein. (66 aa)
ENSFCAP00000044477Uncharacterized protein. (43 aa)
LOC109494688NTR domain-containing protein. (230 aa)
CDC37L1Cell division cycle 37 like 1. (337 aa)
SRLSarcalumenin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (830 aa)
IGF1Insulin like growth factor 1. (195 aa)
FAM49BFamily with sequence similarity 49 member B. (378 aa)
CYB5R1NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
PHACTR3Phosphatase and actin regulator. (560 aa)
ENSFCAP00000039787Uncharacterized protein. (58 aa)
FLNAFilamin A. (2808 aa)
CD9CD9 antigen; Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, [...] (250 aa)
LHFPL6LHFPL tetraspan subfamily member 6. (200 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
TSPAN18Tetraspanin. (333 aa)
SYTL5Synaptotagmin like 5. (754 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (155 aa)
LRRC55Leucine rich repeat containing 55. (318 aa)
IGF2Insulin like growth factor 2. (280 aa)
PHACTR2Phosphatase and actin regulator. (701 aa)
HGFHepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity). (728 aa)
ENSFCAP00000033495Sod_Cu domain-containing protein. (182 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
MANFMesencephalic astrocyte derived neurotrophic factor. (181 aa)
CPAMD8C3 and PZP like alpha-2-macroglobulin domain containing 8. (501 aa)
CDCA7LCell division cycle associated 7 like. (452 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
OLA1Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (396 aa)
ISLR2Immunoglobulin superfamily containing leucine rich repeat 2. (855 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (171 aa)
URB2URB2 ribosome biogenesis homolog. (1521 aa)
APOOLMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (268 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
ENSFCAP00000029012Uncharacterized protein; Belongs to the calmodulin family. (124 aa)
SRGNSerglycin. (164 aa)
LOC101097703EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
TMX3Thioredoxin related transmembrane protein 3. (521 aa)
CSMD1CUB and Sushi multiple domains 1. (3501 aa)
TAGLN3Transgelin 3. (228 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
F13A1Coagulation factor XIII A chain. (787 aa)
ACTN4Actinin alpha 4. (933 aa)
CTSWCathepsin W; May have a specific function in the mechanism or regulation of T-cell cytolytic activity; Belongs to the peptidase C1 family. (374 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
NDNNecdin, MAGE family member. (324 aa)
ENDOD1Endonuclease domain containing 1. (500 aa)
NHLRC2NHL repeat containing 2. (782 aa)
RAB27BRAB27B, member RAS oncogene family. (265 aa)
VCLVinculin. (1066 aa)
CD109CD109 molecule. (1446 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (806 aa)
LYRM7LYR motif containing 7; Belongs to the complex I LYR family. (104 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (428 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
TENM3Teneurin transmembrane protein 3. (2699 aa)
BTBD19BTB domain containing 19. (291 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
FAM3CFamily with sequence similarity 3 member C. (227 aa)
MAGED2MAGE family member D2. (586 aa)
PCYOX1Prenylcysteine oxidase 1. (554 aa)
ECM1Extracellular matrix protein 1. (562 aa)
M3WQU5_FELCAEF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
APOA1Apolipoprotein A1. (295 aa)
ITIH3Inter-alpha-trypsin inhibitor heavy chain 3. (891 aa)
PDGFBPlatelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (245 aa)
CLUClusterin; Belongs to the clusterin family. (469 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (469 aa)
GZMKGranzyme K; Belongs to the peptidase S1 family. (267 aa)
HRGHistidine rich glycoprotein. (536 aa)
TMEM211Uncharacterized protein. (200 aa)
FRZBFrizzled related protein. (324 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (166 aa)
ANXA4Annexin. (321 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (473 aa)
MMRN1Multimerin 1. (1214 aa)
TLN1Talin 1. (2558 aa)
SCG3Secretogranin III. (469 aa)
LHFPL1LHFPL tetraspan subfamily member 1. (284 aa)
QSOX2Sulfhydryl oxidase. (701 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
THBS1Thrombospondin 1. (1170 aa)
IGSF3Immunoglobulin superfamily member 3. (1209 aa)
WDR1WD repeat domain 1. (606 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
BTBD9BTB domain containing 9. (612 aa)
SCCPDHSaccharopine dehydrogenase (putative). (429 aa)
ANXA13Annexin. (357 aa)
SERPINA3Serpin family A member 3; Belongs to the serpin family. (452 aa)
SERPINA4Serpin family A member 4; Belongs to the serpin family. (453 aa)
GTPBP2GTP binding protein 2. (602 aa)
ANXA9Annexin. (345 aa)
APLP2Amyloid beta precursor like protein 2. (763 aa)
CLUL1Clusterin; Belongs to the clusterin family. (468 aa)
FN1Fibronectin 1. (2475 aa)
ABCC4ATP binding cassette subfamily C member 4. (1493 aa)
CDNFCerebral dopamine neurotrophic factor. (183 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
ANXA7Annexin. (489 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (305 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2107 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
SYTL3Synaptotagmin like 3. (611 aa)
LY6G6FIg-like domain-containing protein. (302 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (353 aa)
TLN2Talin 2. (2542 aa)
GAS6Growth arrest specific 6. (674 aa)
ORM2Lipocln_cytosolic_FA-bd_dom domain-containing protein. (239 aa)
LRRC38Leucine rich repeat containing 38. (297 aa)
SERBP1SERPINE1 mRNA binding protein 1. (407 aa)
CD37Tetraspanin. (281 aa)
APPAmyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (935 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
STXBP2Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (604 aa)
BRPF3Bromodomain and PHD finger containing 3. (1241 aa)
CSMD2CUB and Sushi multiple domains 2. (3632 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1086 aa)
EXOGExo/endonuclease G. (368 aa)
FGAFibrinogen alpha chain. (901 aa)
SYTL4Synaptotagmin like 4. (671 aa)
PCYOX1LPrenylcysteine oxidase 1 like. (494 aa)
LRRIQ4Leucine rich repeats and IQ motif containing 4. (574 aa)
LAMP2Lysosomal associated membrane protein 2. (470 aa)
ANXA10Annexin A10. (324 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (706 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
ENDOGEndonuclease. (298 aa)
FERMT3Fermitin family member 3. (733 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (565 aa)
APLP1Amyloid beta precursor like protein 1. (653 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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