STRINGSTRING
NRG2 NRG2 ENSFCAP00000048998 ENSFCAP00000048998 USP8 USP8 PTPN18 PTPN18 ERBIN ERBIN NRG1 NRG1 ERBB4 ERBB4 EGFR EGFR RNF41 RNF41 NRG3 NRG3 BTC BTC ERBB3 ERBB3 LOC109502223 LOC109502223 ENSFCAP00000031119 ENSFCAP00000031119 ENSFCAP00000026617 ENSFCAP00000026617 ERBB2 ERBB2 MATK MATK PTPN12 PTPN12 STUB1 STUB1 CDC37 CDC37 UBA52 UBA52 CUL5 CUL5 AKT2 AKT2 EREG EREG EGF EGF AKT3 AKT3 AKT1 AKT1 RPS27A RPS27A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRG2Neuregulin 2. (862 aa)
ENSFCAP00000048998CDC37_N domain-containing protein. (55 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1116 aa)
PTPN18Uncharacterized protein. (94 aa)
ERBINErbb2 interacting protein. (1461 aa)
NRG1Neuregulin 1. (713 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
RNF41Ring finger protein 41. (317 aa)
NRG3Neuregulin 3. (720 aa)
BTCBetacellulin. (194 aa)
ERBB3ERBB3. (1339 aa)
LOC109502223Ubiquitin-like domain-containing protein. (176 aa)
ENSFCAP00000031119Uncharacterized protein. (383 aa)
ENSFCAP00000026617Ubiquitin-like domain-containing protein. (78 aa)
ERBB2Receptor protein-tyrosine kinase. (1308 aa)
MATKTyrosine-protein kinase. (838 aa)
PTPN12Protein tyrosine phosphatase non-receptor type 12. (782 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
CDC37Uncharacterized protein. (377 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
CUL5Cullin-5; Belongs to the cullin family. (780 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
EREGEpiregulin. (169 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1213 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
RPS27ARibosomal protein S27a. (156 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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