STRINGSTRING
PSMA6 PSMA6 PSME1 PSME1 CSNK2B CSNK2B PSMD2 PSMD2 MKRN2 MKRN2 NEDD4 NEDD4 STUB1 STUB1 PREX2 PREX2 UBA52 UBA52 PSMA1 PSMA1 XIAP XIAP PSMB10 PSMB10 PSMB7 PSMB7 RNF146 RNF146 PTEN PTEN GUF1 GUF1 PSMD9 PSMD9 PSMB11 PSMB11 RNF141 RNF141 PSMD7 PSMD7 MKRN1 MKRN1 RPS27A RPS27A CSNK2A2 CSNK2A2 OTUD3 OTUD3 LOC101083848 LOC101083848 PSMD12 PSMD12 PSMD10 PSMD10 TRIM27 TRIM27 LY6G5B LY6G5B PSMD11 PSMD11 PSMA2 PSMA2 USP13 USP13 PSMA8 PSMA8 OTUD4 OTUD4 LOC101083171 LOC101083171 ENSFCAP00000026617 ENSFCAP00000026617 PSMB6 PSMB6 ENSFCAP00000026978 ENSFCAP00000026978 TNKS TNKS LOC109502223 LOC109502223 PSMA5 PSMA5 PSMF1 PSMF1 PSMC1 PSMC1 CEP170 CEP170 ENSFCAP00000036869 ENSFCAP00000036869 KXD1 KXD1 LOC111556170 LOC111556170 LOC111556171 LOC111556171 ENSFCAP00000041674 ENSFCAP00000041674 PSMC3 PSMC3 PSMD14 PSMD14 TNKS2 TNKS2 CSNK2A1 CSNK2A1 PSMA4 PSMA4 PSME4 PSME4 LOC101082405 LOC101082405 PSMD4 PSMD4 PSMB5 PSMB5 PSMD1 PSMD1 PSME2 PSME2 PSME3 PSME3 PSMB1 PSMB1 ENSFCAP00000053469 ENSFCAP00000053469 PSMA3 PSMA3 ENSFCAP00000055099 ENSFCAP00000055099 PSMA7 PSMA7 PSMB2 PSMB2 PSMC6 PSMC6 PSMB3 PSMB3 AKT2 AKT2 MKRN3 MKRN3 PSMD3 PSMD3 PSMD6 PSMD6 PSMC2 PSMC2 PSMD8 PSMD8 PSMC4 PSMC4 PSMD5 PSMD5 PSMB4 PSMB4 PSMD13 PSMD13 WWP2 WWP2 TRIM7 TRIM7 PSMC5 PSMC5 AKT3 AKT3 FRK FRK AKT1 AKT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMA6Proteasome subunit alpha type. (251 aa)
PSME1Proteasome activator subunit 1. (249 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1323 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1605 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
XIAPX-linked inhibitor of apoptosis. (454 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB7Proteasome subunit beta. (277 aa)
RNF146Ring finger protein 146. (356 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (669 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (284 aa)
PSMB11Proteasome subunit beta. (276 aa)
RNF141Ring finger protein 141. (230 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
MKRN1Makorin ring finger protein 1. (482 aa)
RPS27ARibosomal protein S27a. (156 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
OTUD3OTU deubiquitinase 3. (398 aa)
LOC101083848Proteasome subunit beta. (209 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
TRIM27Tripartite motif containing 27. (513 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (216 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
OTUD4OTU deubiquitinase 4. (1107 aa)
LOC101083171Proteasome subunit beta. (276 aa)
ENSFCAP00000026617Ubiquitin-like domain-containing protein. (78 aa)
PSMB6Proteasome subunit beta. (239 aa)
ENSFCAP00000026978Uncharacterized protein. (111 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
LOC109502223Ubiquitin-like domain-containing protein. (176 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMF1Proteasome inhibitor subunit 1. (341 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
CEP170Centrosomal protein 170. (1588 aa)
ENSFCAP00000036869Proteasome subunit alpha type. (197 aa)
KXD1KxDL motif containing 1. (201 aa)
LOC111556170Proteasome subunit beta type-8. (276 aa)
LOC111556171Uncharacterized protein. (234 aa)
ENSFCAP00000041674AAA domain-containing protein; Belongs to the AAA ATPase family. (189 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
TNKS2Poly [ADP-ribose] polymerase. (1344 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
PSMA4Proteasome subunit alpha type. (277 aa)
PSME4Proteasome activator subunit 4. (1865 aa)
LOC101082405AAA domain-containing protein. (330 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (423 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSME3Uncharacterized protein. (265 aa)
PSMB1Proteasome subunit beta. (261 aa)
ENSFCAP00000053469PA28_beta domain-containing protein. (192 aa)
PSMA3Proteasome subunit alpha type. (258 aa)
ENSFCAP00000055099Uncharacterized protein. (115 aa)
PSMA7Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (358 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa)
PSMB3Proteasome subunit beta. (268 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
MKRN3Makorin ring finger protein 3. (433 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (595 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (478 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (355 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
WWP2E3 ubiquitin-protein ligase. (875 aa)
TRIM7Tripartite motif containing 7. (506 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
FRKTyrosine-protein kinase. (514 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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