27 items (Felis catus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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	SPR	Sepiapterin reductase. (267 aa)
	IDH1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	PRKG2	cGMP-dependent protein kinase. (762 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (342 aa)
	PDSS1	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (408 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
	COQ2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (362 aa)
	COQ3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (370 aa)
	ITPRIPL2	ITPRIP like 2. (532 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	M3WQU5_FELCA	EF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa)
	PTS	6-pyruvoyl tetrahydrobiopterin synthase. (147 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	LOC101097703	EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
	ENSFCAP00000029012	Uncharacterized protein; Belongs to the calmodulin family. (124 aa)
	ENSFCAP00000030830	Uncharacterized protein. (143 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (521 aa)
	GCH1	GTP_cyclohydroI domain-containing protein. (450 aa)
	CALM1	Uncharacterized protein; Belongs to the calmodulin family. (192 aa)
	PDSS2	Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (400 aa)
	ITPRIP	Inositol 1,4,5-trisphosphate receptor interacting protein. (552 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (272 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (276 aa)
	COQ9	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (440 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)
	ENSFCAP00000060347	Uncharacterized protein; Belongs to the calmodulin family. (146 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	NOS3	ENSFCAP00000004586	ENSFCAP00000012234	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase; Produces nitric oxide (NO).	0.950
AKT1	SPR	ENSFCAP00000004586	ENSFCAP00000034949	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Sepiapterin reductase.	0.458
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	NOS3	ENSFCAP00000059662	ENSFCAP00000012234	Non-specific serine/threonine protein kinase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.950
AKT2	SPR	ENSFCAP00000059662	ENSFCAP00000034949	Non-specific serine/threonine protein kinase.	Sepiapterin reductase.	0.458
CALM1	NOS3	ENSFCAP00000050555	ENSFCAP00000012234	Uncharacterized protein; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.508
CALM2	CALM3	ENSFCAP00000016531	ENSFCAP00000055336	Calmodulin 2; Belongs to the calmodulin family.	Calmodulin 3; Belongs to the calmodulin family.	0.801
CALM2	NOS3	ENSFCAP00000016531	ENSFCAP00000012234	Calmodulin 2; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.948
CALM3	CALM2	ENSFCAP00000055336	ENSFCAP00000016531	Calmodulin 3; Belongs to the calmodulin family.	Calmodulin 2; Belongs to the calmodulin family.	0.801
CALM3	NOS3	ENSFCAP00000055336	ENSFCAP00000012234	Calmodulin 3; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.508
CALML3	NOS3	ENSFCAP00000027789	ENSFCAP00000012234	Calmodulin like 3; Belongs to the calmodulin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.948
COQ2	COQ3	ENSFCAP00000013561	ENSFCAP00000015741	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.937
COQ2	COQ5	ENSFCAP00000013561	ENSFCAP00000010230	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.910
COQ2	COQ6	ENSFCAP00000013561	ENSFCAP00000045718	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.944
COQ2	COQ7	ENSFCAP00000013561	ENSFCAP00000054858	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner.	0.723
COQ2	COQ9	ENSFCAP00000013561	ENSFCAP00000056153	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.	0.757
COQ2	PDSS1	ENSFCAP00000013561	ENSFCAP00000011250	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.	0.974
COQ2	PDSS2	ENSFCAP00000013561	ENSFCAP00000052171	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.	0.972
COQ3	COQ2	ENSFCAP00000015741	ENSFCAP00000013561	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.937